Comments on: Experimental Drug Protects Mice From Emphysema’s Ravages http://blogs.discovermagazine.com/80beats/2008/12/23/experimental-drug-protects-mice-from-emphysemas-ravages/ 80beats is DISCOVER's news aggregator, weaving together the choicest tidbits from the best articles covering the day\'s most compelling topics. Sun, 22 Nov 2009 19:01:14 -0600 http://wordpress.org/?v=2.8.4 hourly 1 By: Uncle Al http://blogs.discovermagazine.com/80beats/2008/12/23/experimental-drug-protects-mice-from-emphysemas-ravages/comment-page-1/#comment-16239 Uncle Al Tue, 23 Dec 2008 17:12:44 +0000 http://blogs.discovermagazine.com/80beats/2008/12/23/experimental-drug-protects-mice-from-emphysemas-ravages/#comment-16239 1) Humans cannot produce Vitamins C or E. 2) I you want phenolic antioxidants by the hogshead, eat cocoa. 3) Phenolic antioxidants like BHA, BHT, Trolox, nordihydroguaiaretic acid... are hepatotoxic. If you buy pharma with a low serial number you might get Microcrap Vista in a pill. 4) 1-[2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole (CDDO-Im) exhibits a broad spectrum of cellular proliferation, differentiation, and apoptotsis effects, <I>PNAS</I> 102 4584-4589 (2005) 5) http://www.amsar.com/img/oleanolic.jpg http:// www.freepatentsonline.com/6974801.html 6) Somebody should cyclopropanate the carbonyl-conjugated olefin into both stereoisomers for SAR pharma fun. 1) Humans cannot produce Vitamins C or E.
2) I you want phenolic antioxidants by the hogshead, eat cocoa.
3) Phenolic antioxidants like BHA, BHT, Trolox, nordihydroguaiaretic acid… are hepatotoxic. If you buy pharma with a low serial number you might get Microcrap Vista in a pill.
4) 1-[2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole (CDDO-Im) exhibits a broad spectrum of cellular proliferation, differentiation, and apoptotsis effects, PNAS 102 4584-4589 (2005)
5) http://www.amsar.com/img/oleanolic.jpg
http:// http://www.freepatentsonline.com/6974801.html
6) Somebody should cyclopropanate the carbonyl-conjugated olefin into both stereoisomers for SAR pharma fun.

]]> By: edwards http://blogs.discovermagazine.com/80beats/2008/12/23/experimental-drug-protects-mice-from-emphysemas-ravages/comment-page-1/#comment-16234 edwards Tue, 23 Dec 2008 16:20:50 +0000 http://blogs.discovermagazine.com/80beats/2008/12/23/experimental-drug-protects-mice-from-emphysemas-ravages/#comment-16234 Another company is showing success against COPD with rta402 (rta402.com), which is in phase 2 studies now. With luck, Obama will clean up the lethargic FDA and get important drugs approved a lot faster than in the past. Another company is showing success against COPD with rta402 (rta402.com), which is in phase 2 studies now. With luck, Obama will clean up the lethargic FDA and get important drugs approved a lot faster than in the past.

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