First Hard Evidence: Human Growth Hormone Gives Sprinters a Winning Edge

By Andrew Moseman | May 4, 2010 12:28 pm

SprintersFeetAs we slowly slide out of the steroid era in baseball, human growth hormone (HGH) lingers as the next doping trend in major sports. Players like the New York Yankees’ Andy Pettitte have been implicated as HGH users already, and teammate Alex Rodriguez in currently one of many players being questioned in a federal investigation into the substance. However, until now there was no hard evidence that athletes gained a competitive edge by taking it. Researchers say a new study changes that.

“This is the first demonstration that growth hormone improves performance and justifies its ban in sport,” said Dr. Ken Ho, who led the study [AP].

The new research shows that the gains for athletes cheating with HGH could be staggering—but uneven and fraught with side effects. In the study published in the Annals of Internal Medicine, researchers divided 96 athletes into groups that received either placebo, HGH, testosterone, or a testosterone/HGH mix:

After eight weeks, researchers found that growth hormone improved sprint capacity in men and women by an average of 3.9% over the placebo group — which would trim 0.4 of a second from a 10-second time in the 100-meter dash, said study lead author Dr. Kenneth Ho at St. Vincent’s Hospital in Sydney, Australia. In the 2008 Olympics, the top three male finishers had times of 9.69, 9.89 and 9.91 seconds.

That same 3.9% improvement could cut 1.2 seconds from a 30-second time in a 50-meter swim, Ho said [Los Angeles Times].

Those would be stunning improvements—enough to vault a competitor from the back of the pack to the front. Participants took their assigned substances for eight weeks. Six weeks after the athletes went off the substances, researchers say that their sprinting advantages regressed back to normal.

The findings were mixed, too. While Ho saw that impressive improvement in sprinting capacity, testing the subjects for increased strength or endurance showed now gains in those areas. Thus, the added value of HGH may depend on your sport of choice, he says:

“I don’t think it would help them if they were a rower or a weightlifter. But it would certainly help them if they were a sprinter” [AFP].

The World Anti-Doping Agency, which is currently pressing Major League Baseball to adopt HGH testing, paid for this study. So it would be nice to see independently-funded researchers replicate the findings. In addition, there’s the question of whether sports leagues could even put effective testing in place, because the body naturally produces HGH and testers would be hunting for artificially accelerated levels.

There’s one more problem with this study: Athletes who use HGH in an attempt to win at all costs probably takes far higher doses than those Ho was willing to give his test subjects. The testosterone/HGH mix in Ho’s study was enough to give participant Geoff Webster some unpleasant surprises:

“I actually started to develop breasts which sort of gave me an indication that something might have been happening. I was soaping myself up in the shower, and I thought, ‘Hmm, there’s something growing where it probably shouldn’t be at the moment'” [Australian Broadcasting Corporation].

Related Content:
Discoblog: Is Growth Hormone a Placebo? Sports Cheaters Might Be Fooling Their Own Brains
80beats: Geneticists Are on the Lookout for the First Gene-Doping Athletes
80beats: Can “Biological Passports” Save Sports From Doping?
80beats: Doping Police Try Out “Biological Passports” for Athletes

Image: flickr / katielann12

CATEGORIZED UNDER: Health & Medicine
  • jumblepudding

    gynecomastia (abnormal breast growth) is usually not associated with HGH. Interesting.

  • YouRang

    jumblepudding is correct. BUT some of the people were given testosterone also. And no doubt, Hoff received either the mix or the straight testosterone. So the reporting seems to be way off rather than the physiology.

  • Andrew Moseman

    @YouRang Indeed, Geoff was in the group that received a mix of both. Should have been clear that he wasn’t an HGH-only patient; fixed.

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  • Dr. G. Patino MD.

    As one of the initial suppliers to global anti-aging clinics; we’ve run our own private medical tests on hGH. Back in 1993 after reading Dr. Rudman’s NEJM article; we decided to visit St. Cloud, France; the home of Eli-Lilly. There we took in all they had to offer on their product Humatrope a 191 amino-acid chain product. Upon our return to Mexico we began purchasing this product from Eli-Lily Mexico and utilized 4iu’s per day Mon-Wed-Fri; on 20 test subjects; 10 on hGH alone and the other 10 on a placebo.

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    Dr. G. Patino MD.,


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