Study: Patriot Act Made Anthrax Research 5-6x More Expensive

By Andrew Moseman | May 11, 2010 1:50 pm

anthrax220The USA Patriot Act and the Bioterrorism Preparedness Act, both enacted not long after the 9/11 attacks, contained measures to make it harder for anybody to get their hands on the kind of  pathogens one might need to launch a bioterror attack. There was just one problem: The rules also slowed down and constrained our own scientists’ abilities to learn about those pathogens, according to a study out this week in the Proceedings of the National Academy of Sciences.

To be specific, lead researcher Elizabeth Casman found while there was a touch of good news—the laws didn’t appear to deter new scientists from entering the field—the major effect of those acts has been to make research on ebola virus and anthrax much more expensive, and much slower.

The researchers did find an increase in the total number of papers published. But before the laws, 17 anthrax papers appeared per million dollars of funding. With the restrictions, only three papers appeared per million dollars of funding. For ebola, the numbers dropped from 14 to six papers per million dollars. Figures for the control stayed the same [Scientific American].

In other words, a scientific paper on anthrax became five or six times more expensive, and a paper on ebola twice as expensive. And a lot of the problem is simply the exhaustive record-keeping required.

The laws’ new regulations govern the exhaustive documentation of the transportation, guarding, and use of select agents. As a result, they are burying researchers studying select agents with administrative duties, Casman noted. Researchers to whom Casman spoke “all complained of the paperwork,” she said. “A lot of it, they just find overwhelming” [The Scientist].

One might argue that the paperwork headaches are worth it if they keep our samples of deadly pathogens secure (especially after an affair like the Bruce Ivins case, in which the longtime Army researcher was convicted for was the lead suspect in the 2001 anthrax attacks before he died in 2008 in an apparent suicide). But biodefense policy expert Vickie Sutton told Nature that the Patriot Bioterrorism Preparedness acts aren’t securing out lab supplies of ebola and anthrax—they’re just slowing down our own knowledge about them.

For example, regulations require researchers to create an inventory of each sample of a select agent and to document any changes. A missing test tube would draw immediate attention from the US Centers for Disease Control and Prevention, says Sutton. But the system does nothing to prevent the use of samples withdrawn from a live culture to seed a new culture. “You could every day be giving this agent out to someone,” she says. “It’s nonsense” [Nature].

Related Content:
80beats: Bioterror Attack Likely in the Next 5 Years, Congressional Report Says
80beats: Army Biodefense Lab Shuts Down To Check if Anything Is Missing
80beats: Army Researcher’s Alleged Anthrax Attack Raises Concerns Over Biodefense Labs
DISCOVER: Infectious Defense asks whether a determined bioterrorist can be stopped

Image: U.S. Army

CATEGORIZED UNDER: Health & Medicine
  • Anonymous


    One might argue that the paperwork headaches are worth it if they keep our samples of deadly pathogens secure (especially after an affair like the Bruce Ivins case, in which the longtime Army researcher was convicted for the 2001 anthrax attacks).

  • Andrew Moseman


    I apologize for that mistake. As you noted, Ivins was not convicted, but rather died by apparent suicide in 2008 before the FBI was able to formally charge him in the affair.


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