Comments on: In Mice, Breast Cancer “Vaccine” Trains the Body to Fight Cancerous Cells http://blogs.discovermagazine.com/80beats/2010/06/01/in-mice-breast-cancer-vaccine-trains-the-body-to-fight-cancerous-cells/ 80beats is DISCOVER's news aggregator, weaving together the choicest tidbits from the best articles covering the day's most compelling topics. Mon, 21 May 2012 04:06:35 +0000 hourly 1 http://wordpress.org/?v=3.2.1 By: Brian Too http://blogs.discovermagazine.com/80beats/2010/06/01/in-mice-breast-cancer-vaccine-trains-the-body-to-fight-cancerous-cells/comment-page-1/#comment-188318 Brian Too Wed, 02 Jun 2010 23:16:48 +0000 http://blogs.discovermagazine.com/80beats/?p=15553#comment-188318 @1. jeffrey dach, You defined apoptosis 3 times. Why? We pay attention here you know. @1. jeffrey dach,

You defined apoptosis 3 times. Why? We pay attention here you know.

]]> By: Tom Ames http://blogs.discovermagazine.com/80beats/2010/06/01/in-mice-breast-cancer-vaccine-trains-the-body-to-fight-cancerous-cells/comment-page-1/#comment-188218 Tom Ames Wed, 02 Jun 2010 19:22:28 +0000 http://blogs.discovermagazine.com/80beats/?p=15553#comment-188218 To the Iodine enthusiast: LOTS of things induce apoptosis in cell cultures. The trick is to find compounds that do the same to human cancer cells in vivo, with minimal off-target effects. Cancer cells in vitro are in a very different environment than those arising endogenously. And cancer behavior in animal models often differs in substantial ways from human cancer. There may be some promising research directions here, but you can't be too careful when using data from in vitro or animal models to infer the action of a compound in the clinic. To the Iodine enthusiast: LOTS of things induce apoptosis in cell cultures. The trick is to find compounds that do the same to human cancer cells in vivo, with minimal off-target effects.

Cancer cells in vitro are in a very different environment than those arising endogenously. And cancer behavior in animal models often differs in substantial ways from human cancer.

There may be some promising research directions here, but you can’t be too careful when using data from in vitro or animal models to infer the action of a compound in the clinic.

]]> By: Sandra Rayford http://blogs.discovermagazine.com/80beats/2010/06/01/in-mice-breast-cancer-vaccine-trains-the-body-to-fight-cancerous-cells/comment-page-1/#comment-188022 Sandra Rayford Wed, 02 Jun 2010 09:32:36 +0000 http://blogs.discovermagazine.com/80beats/?p=15553#comment-188022 What can I do to to encourage corporations and government to fund Dr. Tuohy's work? What can I do to to encourage corporations and government to fund Dr. Tuohy’s work?

]]> By: jeffrey dach md http://blogs.discovermagazine.com/80beats/2010/06/01/in-mice-breast-cancer-vaccine-trains-the-body-to-fight-cancerous-cells/comment-page-1/#comment-188013 jeffrey dach md Wed, 02 Jun 2010 09:04:09 +0000 http://blogs.discovermagazine.com/80beats/?p=15553#comment-188013 Iodine deficient diets in animals induces breast cancer and goiter.The Shrivastava group in India reported molecular iodine induces apoptosis (programmed cell death) in human breast cancer cell cultures. "Iodine showed cytotoxic effects in the cultured human breast cancer cells". From Mexico, the Carmen Aceves Velasco Group reported Iodine to be safe, with no harmful effects on thyroid function, and an anti-proliferative effect on human breast cancer cell cultures. Their 2009 paper reported the mechanism by which Iodine works as an anti-cancer agent. Iodine binds to membrane lipids called lactones forming iodo-lactones which regulate apoptosis (programmed cell death). Iodine causes apoptosis which makes cancer cells undergo programmed cell death. Dr. Aceves concluded that continuous molecular iodine treatment has a "potent antineoplastic effect" on the progression of mammary cancer. From Japan, Dr Funahashi reported a common seaweed food containing high iodine content is more beneficial than chemotherapy on breast cancer . "He found that administration of Lugol’s iodine or iodine-rich Wakame seaweed to rats treated with the carcinogen dimethyl benzanthracene suppressed the development of mammary tumors. The same group demonstrated that seaweed induced apoptosis in human breast cancer cells with greater potency than that of fluorouracil, a chemotherapeutic agent used to treat breast cancer." A 2008 paper by Bernard A. Eskin MD showed that Iodine actually altered gene expression in breast cancer cells, inducing programmed cell death. A 2003 study by Ling Zhang ahowed that molecular Iodine caused lung cancer cells to undergo programmed cell death (apoptosis). These lung cancer cells had been genetically modified to increase iodine uptake. Current Iodine research calls for use of molecular Iodine for all patients with breast cancer. For references and More: http://jeffreydach.com/2009/11/13/iodine-against-breast-cancer-the-overwhelming-evidence-by-jeffrey-dach-md.aspx jeffrey dach md Iodine deficient diets in animals induces breast cancer and goiter.The Shrivastava group in India reported molecular iodine induces apoptosis (programmed cell death) in human breast cancer cell cultures. “Iodine showed cytotoxic effects in the cultured human breast cancer cells”.

From Mexico, the Carmen Aceves Velasco Group reported Iodine to be safe, with no harmful effects on thyroid function, and an anti-proliferative effect on human breast cancer cell cultures. Their 2009 paper reported the mechanism by which Iodine works as an anti-cancer agent. Iodine binds to membrane lipids called lactones forming iodo-lactones which regulate apoptosis (programmed cell death). Iodine causes apoptosis which makes cancer cells undergo programmed cell death. Dr. Aceves concluded that continuous molecular iodine treatment has a “potent antineoplastic effect” on the progression of mammary cancer.

From Japan, Dr Funahashi reported a common seaweed food containing high iodine content is more beneficial than chemotherapy on breast cancer . “He found that administration of Lugol’s iodine or iodine-rich Wakame seaweed to rats treated with the carcinogen dimethyl benzanthracene suppressed the development of mammary tumors. The same group demonstrated that seaweed induced apoptosis in human breast cancer cells with greater potency than that of fluorouracil, a chemotherapeutic agent used to treat breast cancer.”

A 2008 paper by Bernard A. Eskin MD showed that Iodine actually altered gene expression in breast cancer cells, inducing programmed cell death. A 2003 study by Ling Zhang ahowed that molecular Iodine caused lung cancer cells to undergo programmed cell death (apoptosis). These lung cancer cells had been genetically modified to increase iodine uptake. Current Iodine research calls for use of molecular Iodine for all patients with breast cancer.

For references and More:

http://jeffreydach.com/2009/11/13/iodine-against-breast-cancer-the-overwhelming-evidence-by-jeffrey-dach-md.aspx

jeffrey dach md

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