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	<title>Comments on: Autism Risk Gene May Generate a Tangle of Wiring the Brain</title>
	<atom:link href="http://blogs.discovermagazine.com/80beats/2010/11/04/autism-risk-gene-may-generate-a-tangle-of-wiring-the-brain/feed/" rel="self" type="application/rss+xml" />
	<link>http://blogs.discovermagazine.com/80beats/2010/11/04/autism-risk-gene-may-generate-a-tangle-of-wiring-the-brain/</link>
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		<title>By: College</title>
		<link>http://blogs.discovermagazine.com/80beats/2010/11/04/autism-risk-gene-may-generate-a-tangle-of-wiring-the-brain/#comment-23260</link>
		<dc:creator>College</dc:creator>
		<pubDate>Sun, 24 Jul 2011 02:30:02 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/80beats/?p=22325#comment-23260</guid>
		<description>I’d be inclined to acknowledge with you here. Which is not something I typically do! I enjoy reading a post that will make people think. Also, thanks for allowing me to comment!e if it&#039;s the right choice for you.</description>
		<content:encoded><![CDATA[<p>I’d be inclined to acknowledge with you here. Which is not something I typically do! I enjoy reading a post that will make people think. Also, thanks for allowing me to comment!e if it&#8217;s the right choice for you.</p>
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		<title>By: RAJ</title>
		<link>http://blogs.discovermagazine.com/80beats/2010/11/04/autism-risk-gene-may-generate-a-tangle-of-wiring-the-brain/#comment-23259</link>
		<dc:creator>RAJ</dc:creator>
		<pubDate>Tue, 16 Nov 2010 19:55:26 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/80beats/?p=22325#comment-23259</guid>
		<description>CTNAP2  variations have been located in a region of chromosome 7. It is also associated with many developmental problems including autism, schizophrenia, mental retardation and childhhood language disorders as well as the vast majority of people who are not affected in any way.

This is a tiny risk factor that is not diagnosis specific as are all the common genetic variations and copy number variations.

If there is any tiny risk factor it is not with autism but rather risk for neurodevelopmental alterations common in the developmental disorders.

Infact, no genetic variation has ever been identified that is a diagnosis specific susceptability gene.</description>
		<content:encoded><![CDATA[<p>CTNAP2  variations have been located in a region of chromosome 7. It is also associated with many developmental problems including autism, schizophrenia, mental retardation and childhhood language disorders as well as the vast majority of people who are not affected in any way.</p>
<p>This is a tiny risk factor that is not diagnosis specific as are all the common genetic variations and copy number variations.</p>
<p>If there is any tiny risk factor it is not with autism but rather risk for neurodevelopmental alterations common in the developmental disorders.</p>
<p>Infact, no genetic variation has ever been identified that is a diagnosis specific susceptability gene.</p>
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		<title>By: Mark</title>
		<link>http://blogs.discovermagazine.com/80beats/2010/11/04/autism-risk-gene-may-generate-a-tangle-of-wiring-the-brain/#comment-23258</link>
		<dc:creator>Mark</dc:creator>
		<pubDate>Sat, 13 Nov 2010 21:20:15 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/80beats/?p=22325#comment-23258</guid>
		<description>@Anthony:
Anthony, you are thinking without a box at all.

What you suggest vis a vis &quot;a risk&quot; gene with a particular environmental exposure such as a vaccine would be possible, if it were not for the fact that there is a tremendous amount of evidnce that vaccines are not related to autism in any way. Since 1/3rd of the population carries the CTNAP2 polymorphism, prior work would have revealed such a link.

There is no need to develop a vaccination that is safe for people with this polymorphism, since we already know that existing vaccines are safe for them.</description>
		<content:encoded><![CDATA[<p>@Anthony:<br />
Anthony, you are thinking without a box at all.</p>
<p>What you suggest vis a vis &#8220;a risk&#8221; gene with a particular environmental exposure such as a vaccine would be possible, if it were not for the fact that there is a tremendous amount of evidnce that vaccines are not related to autism in any way. Since 1/3rd of the population carries the CTNAP2 polymorphism, prior work would have revealed such a link.</p>
<p>There is no need to develop a vaccination that is safe for people with this polymorphism, since we already know that existing vaccines are safe for them.</p>
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		<title>By: Michael</title>
		<link>http://blogs.discovermagazine.com/80beats/2010/11/04/autism-risk-gene-may-generate-a-tangle-of-wiring-the-brain/#comment-23257</link>
		<dc:creator>Michael</dc:creator>
		<pubDate>Sat, 06 Nov 2010 17:45:47 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/80beats/?p=22325#comment-23257</guid>
		<description>Try this on 100 more kids, and maybe a clearer pattern will emerge.

What did the MRI reveal when the children with the gene were given a math problem?</description>
		<content:encoded><![CDATA[<p>Try this on 100 more kids, and maybe a clearer pattern will emerge.</p>
<p>What did the MRI reveal when the children with the gene were given a math problem?</p>
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		<title>By: Mary McK</title>
		<link>http://blogs.discovermagazine.com/80beats/2010/11/04/autism-risk-gene-may-generate-a-tangle-of-wiring-the-brain/#comment-23256</link>
		<dc:creator>Mary McK</dc:creator>
		<pubDate>Fri, 05 Nov 2010 12:44:56 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/80beats/?p=22325#comment-23256</guid>
		<description>Well, isn&#039;t it appropriate that when you pronounce the Gene, it is CAN&#039;T NAP!</description>
		<content:encoded><![CDATA[<p>Well, isn&#8217;t it appropriate that when you pronounce the Gene, it is CAN&#8217;T NAP!</p>
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		<title>By: Anthony</title>
		<link>http://blogs.discovermagazine.com/80beats/2010/11/04/autism-risk-gene-may-generate-a-tangle-of-wiring-the-brain/#comment-23255</link>
		<dc:creator>Anthony</dc:creator>
		<pubDate>Fri, 05 Nov 2010 12:44:40 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/80beats/?p=22325#comment-23255</guid>
		<description>@John Rolin

John you are thinking inside the box.  Think outside.  This gene has identified as a &#039;Risk&#039; gene.  It&#039;s very possible that anyone with the &#039;Risk&#039; gene that has a certain class of vaccination will develop autism.  If that can be determined they it&#039;s possible they can develop a variant of vaccination that is safe f0r those WITH the &#039;Risk&#039; gene.</description>
		<content:encoded><![CDATA[<p>@John Rolin</p>
<p>John you are thinking inside the box.  Think outside.  This gene has identified as a &#8216;Risk&#8217; gene.  It&#8217;s very possible that anyone with the &#8216;Risk&#8217; gene that has a certain class of vaccination will develop autism.  If that can be determined they it&#8217;s possible they can develop a variant of vaccination that is safe f0r those WITH the &#8216;Risk&#8217; gene.</p>
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		<title>By: JOHN ROLIN</title>
		<link>http://blogs.discovermagazine.com/80beats/2010/11/04/autism-risk-gene-may-generate-a-tangle-of-wiring-the-brain/#comment-23254</link>
		<dc:creator>JOHN ROLIN</dc:creator>
		<pubDate>Fri, 05 Nov 2010 03:59:41 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/80beats/?p=22325#comment-23254</guid>
		<description>This new discovery will not make any difference to the trial lawyers.  They will continue to file lawsuits claiming that immunization injections cause Autism.  Do I hear John Edwards calling?</description>
		<content:encoded><![CDATA[<p>This new discovery will not make any difference to the trial lawyers.  They will continue to file lawsuits claiming that immunization injections cause Autism.  Do I hear John Edwards calling?</p>
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		<title>By: Billie</title>
		<link>http://blogs.discovermagazine.com/80beats/2010/11/04/autism-risk-gene-may-generate-a-tangle-of-wiring-the-brain/#comment-23253</link>
		<dc:creator>Billie</dc:creator>
		<pubDate>Fri, 05 Nov 2010 01:58:15 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/80beats/?p=22325#comment-23253</guid>
		<description>Wow very facinating thankyou keep up the great work</description>
		<content:encoded><![CDATA[<p>Wow very facinating thankyou keep up the great work</p>
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