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	<title>Comments on: Vitamin D: Cutting Through the Confusion &amp; Controversy</title>
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	<link>http://blogs.discovermagazine.com/80beats/2010/12/01/vitamin-d-cutting-through-the-confusion-controversy/</link>
	<description>80beats is DISCOVER&#039;s news aggregator, weaving together the choicest tidbits from the best articles covering the day&#039;s most compelling topics.</description>
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		<title>By: Saibal Mitra</title>
		<link>http://blogs.discovermagazine.com/80beats/2010/12/01/vitamin-d-cutting-through-the-confusion-controversy/comment-page-1/#comment-546013</link>
		<dc:creator>Saibal Mitra</dc:creator>
		<pubDate>Tue, 28 Dec 2010 16:09:44 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/80beats/?p=23311#comment-546013</guid>
		<description>One can also ask why animals would have evolved to make bone health dependend on the Sun being high in the sky. Note that vitamin D itself does not get  the calcium from food into bones, this is done by other compounds that some genes code for; those genes are switched on in response to vitamin D. 

Vitamin D being involved in only bone health does not make a lot of sense. But if we take serious the evidence of it being involved also in modulating the immune system, then things become more clear.  Animals may have evolved to use vitamin D to modulate processes that use a lot of energy, like the immune system. When the Sun is no longer high in the sky, that signals a coming Winter, and it makes sense to let such processes run in a more energy efficient way, so that fat reserves can be built up more easily. 

The less fat an animal has to begin with the sooner its vitamin D levels will drop, as vitamin D is stored in body fat. So, this is consistent with vitamin D being used to implement an optimal strategy to make it through Winter.  As vitamin D levels drop to ever lower values as Winter progresses, more energy saving measures are taken. 

Getting calcium from food costs energy, due to the low concentration of calcium in food. It costs far less energy to maintain the necessary calcium levels in the blood from getting it from our bones, because the concentration of calcium there is much higher. However, this comes at the expense of maintaining the bones. If this situation lasts for a few weeks, it is not going to do significant damage; the benefits of spending less energy to digest food are much greater for animals that have to survive in nature.</description>
		<content:encoded><![CDATA[<p>One can also ask why animals would have evolved to make bone health dependend on the Sun being high in the sky. Note that vitamin D itself does not get  the calcium from food into bones, this is done by other compounds that some genes code for; those genes are switched on in response to vitamin D. </p>
<p>Vitamin D being involved in only bone health does not make a lot of sense. But if we take serious the evidence of it being involved also in modulating the immune system, then things become more clear.  Animals may have evolved to use vitamin D to modulate processes that use a lot of energy, like the immune system. When the Sun is no longer high in the sky, that signals a coming Winter, and it makes sense to let such processes run in a more energy efficient way, so that fat reserves can be built up more easily. </p>
<p>The less fat an animal has to begin with the sooner its vitamin D levels will drop, as vitamin D is stored in body fat. So, this is consistent with vitamin D being used to implement an optimal strategy to make it through Winter.  As vitamin D levels drop to ever lower values as Winter progresses, more energy saving measures are taken. </p>
<p>Getting calcium from food costs energy, due to the low concentration of calcium in food. It costs far less energy to maintain the necessary calcium levels in the blood from getting it from our bones, because the concentration of calcium there is much higher. However, this comes at the expense of maintaining the bones. If this situation lasts for a few weeks, it is not going to do significant damage; the benefits of spending less energy to digest food are much greater for animals that have to survive in nature.</p>
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		<title>By: Brian</title>
		<link>http://blogs.discovermagazine.com/80beats/2010/12/01/vitamin-d-cutting-through-the-confusion-controversy/comment-page-1/#comment-496931</link>
		<dc:creator>Brian</dc:creator>
		<pubDate>Mon, 13 Dec 2010 14:01:13 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/80beats/?p=23311#comment-496931</guid>
		<description>I don&#039;t believe 3000IU would hurt, do you? I&#039;m tempted to jump my intake to 4000IU, now.</description>
		<content:encoded><![CDATA[<p>I don&#8217;t believe 3000IU would hurt, do you? I&#8217;m tempted to jump my intake to 4000IU, now.</p>
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		<title>By: Marianne Buchwalder Antezzo</title>
		<link>http://blogs.discovermagazine.com/80beats/2010/12/01/vitamin-d-cutting-through-the-confusion-controversy/comment-page-1/#comment-462332</link>
		<dc:creator>Marianne Buchwalder Antezzo</dc:creator>
		<pubDate>Fri, 03 Dec 2010 17:06:35 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/80beats/?p=23311#comment-462332</guid>
		<description>The panel which came up with the negative conclusions on D3 did not do any testing of their own.  They just examined the reports of studies done on D3, and concluded that the performed tests were flawed in some way.  Essentially this panel said...you haven&#039;t proved it, according to us, and so it&#039;s not true.  This panel has done no research.  How they decided to even minimally increase recommended D3 consumption was not explained, and seems as if they just winged it.   Experts in the field of D3 were consulted  (on some level), and wrote rebuttals to the panel&#039;s conclusions.  Their rebuttals were excluded from the report.  A group is trying through FOI to gain access to the experts&#039; comments on the panel&#039;s report.
I hope the experts&#039; rebuttals will be published and given the same extensive media coverage as has this dubious report.</description>
		<content:encoded><![CDATA[<p>The panel which came up with the negative conclusions on D3 did not do any testing of their own.  They just examined the reports of studies done on D3, and concluded that the performed tests were flawed in some way.  Essentially this panel said&#8230;you haven&#8217;t proved it, according to us, and so it&#8217;s not true.  This panel has done no research.  How they decided to even minimally increase recommended D3 consumption was not explained, and seems as if they just winged it.   Experts in the field of D3 were consulted  (on some level), and wrote rebuttals to the panel&#8217;s conclusions.  Their rebuttals were excluded from the report.  A group is trying through FOI to gain access to the experts&#8217; comments on the panel&#8217;s report.<br />
I hope the experts&#8217; rebuttals will be published and given the same extensive media coverage as has this dubious report.</p>
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		<title>By: Birgit Calhoun</title>
		<link>http://blogs.discovermagazine.com/80beats/2010/12/01/vitamin-d-cutting-through-the-confusion-controversy/comment-page-1/#comment-460666</link>
		<dc:creator>Birgit Calhoun</dc:creator>
		<pubDate>Thu, 02 Dec 2010 23:34:24 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/80beats/?p=23311#comment-460666</guid>
		<description>Originally the Vitamin D level was established by seeing how much supplementation it took to keep children from getting rickets. 

Science has come a long way since then. Experts now understand that Vitamin D receptors exist in many parts of the body. That means Vitamin D is necessary for organs other than bones. 

The blanket statement that most people get enough Vitamin D is not backed by any research that I have seen. 

Two years ago I started taking 1000 IU a day of Vitamin D. At the same time I went out into the sun at noon for about 30 minutes every day, religiously. My bone density was ok. But when I got tested my 25 (OH) D3 was very low: 14ng. I got therapeutic doses of 50,000 for 6 weeks (twice), then 100,000 IU  for 8 weeks. Finally my level came up to 32 ng. I have been taking 4,000 IU since then. The joints in my fingers are not as painful and my general constitution is much better.

I would not have known to get tested if it hadn&#039;t been for my son who has extreme osteopenia. He has had about 100 broken bones in his body. Over 10 years ago he was tested as having 11ng. At that time the orthopedic surgeon and a second opinion told me that that was within the normal range. The x-rays looked as if my son had rickets. They stated he did not have rickets. My son would not be in a wheelchair if he had received a proper diagnosis. It turns out he had osteomalacia.  Rickets is the same as osteomalacia. Except osteomalacia happens in adults. How many doctors check the parathyroid level when testing Vitamin D? It&#039;s an impotent factor. Why is that not being addressed in the report. And yes, the kidney makes the active form of Vitamin D. So if you have kidney disease you might want to check that. 

Here is my question: Why were the experts not involved is this study. The experts I know of are Cedric Garland, Reinhold Vieth. Dr. Holick. Dr. Hollis, Dr. Cannell. They have good arguments in favor of a much higher dose of Vitamin D than what this panel came up with.  

How much conflict of interest is involved choosing the panel members and the type of reporting we see? The difference between just The Wall Street Journal and The New York Times is stunning.</description>
		<content:encoded><![CDATA[<p>Originally the Vitamin D level was established by seeing how much supplementation it took to keep children from getting rickets. </p>
<p>Science has come a long way since then. Experts now understand that Vitamin D receptors exist in many parts of the body. That means Vitamin D is necessary for organs other than bones. </p>
<p>The blanket statement that most people get enough Vitamin D is not backed by any research that I have seen. </p>
<p>Two years ago I started taking 1000 IU a day of Vitamin D. At the same time I went out into the sun at noon for about 30 minutes every day, religiously. My bone density was ok. But when I got tested my 25 (OH) D3 was very low: 14ng. I got therapeutic doses of 50,000 for 6 weeks (twice), then 100,000 IU  for 8 weeks. Finally my level came up to 32 ng. I have been taking 4,000 IU since then. The joints in my fingers are not as painful and my general constitution is much better.</p>
<p>I would not have known to get tested if it hadn&#8217;t been for my son who has extreme osteopenia. He has had about 100 broken bones in his body. Over 10 years ago he was tested as having 11ng. At that time the orthopedic surgeon and a second opinion told me that that was within the normal range. The x-rays looked as if my son had rickets. They stated he did not have rickets. My son would not be in a wheelchair if he had received a proper diagnosis. It turns out he had osteomalacia.  Rickets is the same as osteomalacia. Except osteomalacia happens in adults. How many doctors check the parathyroid level when testing Vitamin D? It&#8217;s an impotent factor. Why is that not being addressed in the report. And yes, the kidney makes the active form of Vitamin D. So if you have kidney disease you might want to check that. </p>
<p>Here is my question: Why were the experts not involved is this study. The experts I know of are Cedric Garland, Reinhold Vieth. Dr. Holick. Dr. Hollis, Dr. Cannell. They have good arguments in favor of a much higher dose of Vitamin D than what this panel came up with.  </p>
<p>How much conflict of interest is involved choosing the panel members and the type of reporting we see? The difference between just The Wall Street Journal and The New York Times is stunning.</p>
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		<title>By: The taipan</title>
		<link>http://blogs.discovermagazine.com/80beats/2010/12/01/vitamin-d-cutting-through-the-confusion-controversy/comment-page-1/#comment-459370</link>
		<dc:creator>The taipan</dc:creator>
		<pubDate>Thu, 02 Dec 2010 15:51:00 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/80beats/?p=23311#comment-459370</guid>
		<description>Anybody REALLY looking out FOR our health out there?
Sounds very blase&#039; / pessimistic but this is the hard question that we are afraid to ask!
It&#039;s our HEALTH at risk, WHY is there no one to speak for the PEOPLE?
There are LOBBYSTS who lobby for big corporations and convince the government to pass certain laws that they (the lobbyists and their bosses, the big corporations) think will be good for the public(?)
We the PEOPLE just passively go on with our lives and grumble and mutter all we want and NOBODY (government and all) gives a hoot!
This is not been written to attract any argument, it&#039;s just my take on the whole situation!</description>
		<content:encoded><![CDATA[<p>Anybody REALLY looking out FOR our health out there?<br />
Sounds very blase&#8217; / pessimistic but this is the hard question that we are afraid to ask!<br />
It&#8217;s our HEALTH at risk, WHY is there no one to speak for the PEOPLE?<br />
There are LOBBYSTS who lobby for big corporations and convince the government to pass certain laws that they (the lobbyists and their bosses, the big corporations) think will be good for the public(?)<br />
We the PEOPLE just passively go on with our lives and grumble and mutter all we want and NOBODY (government and all) gives a hoot!<br />
This is not been written to attract any argument, it&#8217;s just my take on the whole situation!</p>
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		<title>By: Wiglaf</title>
		<link>http://blogs.discovermagazine.com/80beats/2010/12/01/vitamin-d-cutting-through-the-confusion-controversy/comment-page-1/#comment-458911</link>
		<dc:creator>Wiglaf</dc:creator>
		<pubDate>Thu, 02 Dec 2010 13:32:48 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/80beats/?p=23311#comment-458911</guid>
		<description>ChrisMavo, your body won&#039;t produce vitamin D without the right kind of light exposure; typically sunlight.</description>
		<content:encoded><![CDATA[<p>ChrisMavo, your body won&#8217;t produce vitamin D without the right kind of light exposure; typically sunlight.</p>
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		<title>By: ChrisMavo</title>
		<link>http://blogs.discovermagazine.com/80beats/2010/12/01/vitamin-d-cutting-through-the-confusion-controversy/comment-page-1/#comment-457815</link>
		<dc:creator>ChrisMavo</dc:creator>
		<pubDate>Thu, 02 Dec 2010 00:32:21 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/80beats/?p=23311#comment-457815</guid>
		<description>First off, vitamin D is not even a vitamin! It was misidenified as one when it was discovered about 80 years ago. In reality what we call vitamin D is actually a form of steroid precursor! And I doubt that most medical experts would recommend anyone to supplement with any kind of steroid!

I supplemented with vitamin D for years because I too bought into the hype surrounding &quot;vitamin D&quot;! And after years of supplementation and a 25(OH)D level of 50 ... I was diagnosed last year with ALS or Lou Gehrig&#039;s disease! Now there is certainly no proof this supplementation caused my ALS illness. But, I certainly would exercise the utmost caution before supplementing with vitamin D in any form. Just eat a good balanced diet and your body will produce enough vitamin D on it&#039;s own!</description>
		<content:encoded><![CDATA[<p>First off, vitamin D is not even a vitamin! It was misidenified as one when it was discovered about 80 years ago. In reality what we call vitamin D is actually a form of steroid precursor! And I doubt that most medical experts would recommend anyone to supplement with any kind of steroid!</p>
<p>I supplemented with vitamin D for years because I too bought into the hype surrounding &#8220;vitamin D&#8221;! And after years of supplementation and a 25(OH)D level of 50 &#8230; I was diagnosed last year with ALS or Lou Gehrig&#8217;s disease! Now there is certainly no proof this supplementation caused my ALS illness. But, I certainly would exercise the utmost caution before supplementing with vitamin D in any form. Just eat a good balanced diet and your body will produce enough vitamin D on it&#8217;s own!</p>
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		<title>By: Wiglaf</title>
		<link>http://blogs.discovermagazine.com/80beats/2010/12/01/vitamin-d-cutting-through-the-confusion-controversy/comment-page-1/#comment-457739</link>
		<dc:creator>Wiglaf</dc:creator>
		<pubDate>Wed, 01 Dec 2010 23:36:52 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/80beats/?p=23311#comment-457739</guid>
		<description>You say, &quot;the doctors [have] a vested interest in being right.&quot;

Doctors sometimes seem to like to do what Big Pharma is wiling to pay for.  The doctors have all kinds of vested interests; money, association, reputation, job, fame, grants, funding, appearance, etc.  It&#039;s very simplistic to say that their only interest is in &quot;being right.&quot;  In addition, Vitamin D is not a patentable product.  Any nutrition company can manufacture it.  SO, at least vitamin D is subject to competition for quality and value.  The IOM/FNB is a somewhat monopolistic board supported by government money.  Perhaps such a board would have an &quot;interest&quot; in presenting findings that would encourage more funding for more reports and studies.  I&#039;ll read between the lines myself.  I don&#039;t trust the surface conclusions or implications.

This study doesn&#039;t stress the importance of testing your D levels if you&#039;re concerned about whether or not you&#039;re deficient.  Why not?</description>
		<content:encoded><![CDATA[<p>You say, &#8220;the doctors [have] a vested interest in being right.&#8221;</p>
<p>Doctors sometimes seem to like to do what Big Pharma is wiling to pay for.  The doctors have all kinds of vested interests; money, association, reputation, job, fame, grants, funding, appearance, etc.  It&#8217;s very simplistic to say that their only interest is in &#8220;being right.&#8221;  In addition, Vitamin D is not a patentable product.  Any nutrition company can manufacture it.  SO, at least vitamin D is subject to competition for quality and value.  The IOM/FNB is a somewhat monopolistic board supported by government money.  Perhaps such a board would have an &#8220;interest&#8221; in presenting findings that would encourage more funding for more reports and studies.  I&#8217;ll read between the lines myself.  I don&#8217;t trust the surface conclusions or implications.</p>
<p>This study doesn&#8217;t stress the importance of testing your D levels if you&#8217;re concerned about whether or not you&#8217;re deficient.  Why not?</p>
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		<title>By: Charles</title>
		<link>http://blogs.discovermagazine.com/80beats/2010/12/01/vitamin-d-cutting-through-the-confusion-controversy/comment-page-1/#comment-457575</link>
		<dc:creator>Charles</dc:creator>
		<pubDate>Wed, 01 Dec 2010 22:06:40 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/80beats/?p=23311#comment-457575</guid>
		<description>Well that&#039;s just confusing. I was told to take Vitamin D in the winter because my blood calcium was low. Maybe I&#039;ll just take weaker Vitamin D pills (I don&#039;t take any other vitamins nor drugs except the occasional ibuprofen). I do get enough calcium through my regular diet.

And what does &quot;you’re all doing pretty well&quot; mean, anyway? Since I&#039;m actually basing my blood calcium levels based on blood tests (as well as the fact that during the winter I never actually go out into the sun) mean I should continue? bah.</description>
		<content:encoded><![CDATA[<p>Well that&#8217;s just confusing. I was told to take Vitamin D in the winter because my blood calcium was low. Maybe I&#8217;ll just take weaker Vitamin D pills (I don&#8217;t take any other vitamins nor drugs except the occasional ibuprofen). I do get enough calcium through my regular diet.</p>
<p>And what does &#8220;you’re all doing pretty well&#8221; mean, anyway? Since I&#8217;m actually basing my blood calcium levels based on blood tests (as well as the fact that during the winter I never actually go out into the sun) mean I should continue? bah.</p>
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