A Blast of Light to the Brain Can Make Mice Mean

By Andrew Moseman | February 10, 2011 9:56 am

The burgeoning field of optogenetics—using shot of light on neurons to control behavior—has already produced some intruiging and peculiar results. Now add one more: Scientists can use it to make mice angry and aggressive.

From DISCOVER blogger Ed Yong:

With a pulse of light, Dayu Lin from New York University can turn docile mice into violent fighters – it’s Dr Jekyll’s potion, delivered via fibre optic cable. The light activates a group of neurons in the mouse’s brain that are involved in aggressive behaviour. As a result, the mouse attacks other males, females, and even inanimate objects.

Lin focused on a primitive part of the brain called the hypothalamus that keeps our basic bodily functions ticking over. It lords over body temperature, hunger, thirst, sleep and more. In particular, Lin found that a small part of this area – the ventrolateral ventromedial hypothalamus (VMHvl) – acts as a hub for both sex and violence.

Read plenty more about this study in the rest of Ed’s post at Not Exactly Rocket Science.

Related Content:
80beats: Zapping Worm Brains With Lasers Reveals the Duty of Each Neuron
80beats: Star Trek-Style “Phaser” Paralyzes Worms With a UV Blast
80beats: Shiny New Neuroscience Technique (Optogenetics) Verifies a Familiar Method (fMRI)
80beats: Researchers Flip Brain Cells On and Off With Light Pulses

CATEGORIZED UNDER: Living World, Mind & Brain
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