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80beats

Posts Tagged ‘baldness’

How Scientists Unintentionally Cured Baldness in Mice

It was a stroke of serendipity that may one day help those who hide under comb overs or wear wigs: scientists studying how mice bowels react to a stress-reducing chemical have inadvertently discovered a cure to baldness. But unfortunately, it looks like this cure won’t apply to genetic baldness, which is by far the main cause of most hairless pates. Still, researchers hope the lucky find will eventually be used to battle at least some of the bare heads of humans.

The story begins with mice that were genetically modified to produce too much corticotrophin-releasing factor, or CRF–a type of stress hormone. Normally, as these stressed-out rodents age, their backs lose hair. But a group of researchers from the Veterans Administration and the University of California at Los Angeles didn’t care about hair, they just wanted to study the effects of a chemical on the modified mice.

Researchers at the Salk Institute developed a peptide called “astressin-B”, which blocks the action of CRF, and the teams injected the peptide into the bald mice. They weren’t thinking about baldness at all — they wanted to test whether the astressin had any impact on the mice’s gastrointestinal tracts. The first injection did nothing, so the team gave the mice additional injections over five days, and then measured the effects on the newly de-stressed mice’s colons. [Popular Science]

With most of the experiment done, the researchers forgot about the mice for three months. Then they returned for some follow-up tests:

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February 17th, 2011 Tags: baldness, genetics, hair, hair loss, stress
by Patrick Morgan in Health & Medicine, Living World | 8 Comments » | RSS feed | Trackback >

Hairless Dogs Give up the Genetic Secret of Their Bald Glory


hairless dogResearchers have discovered the gene that determines the baldness of several hairless dog breeds, and say it may offers new insight into the development of skin and hair in other animals – including humans [New Scientist].

Mexican hairless, Peruvian hairless and Chinese crested dog breeds all share the same mutation, researchers say, which probably appeared about 4,000 years ago in Mexican hairless dogs and eventually passed through breeding into the other two dog breeds, Leeb says. “It’s extremely improbable that an identical mutation would have arisen three times,” he says [Science News].

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September 12th, 2008 Tags: baldness, dogs, genetics
by Eliza Strickland in Living World | 3 Comments » | RSS feed | Trackback >





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      80beats is DISCOVER's news aggregator, weaving together the choicest tidbits from the best articles on the day's most compelling topics.

      80beats is written by Veronique Greenwood and Valerie Ross. This team darts through each day's science news faster than the ruby-throated hummingbird that beats its wings 80 times per second. Send ideas, tips, suggestions, and complaints to [azeeberg at discovermagazine dot com].



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