Every year, Nikon asks photographers and scientists to enter their most magnificent microscopic photos into the Small World photomicography competition, and every year, they dazzle. Here are three of the coolest photos from among this year’s winners.
Jennifer Peters and Michael Taylor, St. Jude Children’s Research Hospital/Nikon Small World
First Place: This winning photo depicts the blood-brain barrier, the seal between capillaries and the brain, of a live zebrafish embryo. To produce the image, researchers genetically engineered components of the barrier to fluoresce under a confocal microscope, took a series of photos at 20x magnification, then combined the images to create this one. This is believed to be the first time the developing blood-brain barrier of a live animal has been captured on film.
What’s the News: A modified antibody can make its way into the brain and target the development of Alzheimer’s-inducing plaques, researchers reported today in two animal studies in Science Translational Medicine. The blood-brain barrier usually keeps drugs and other compounds from entering the brain in large enough quantities to be effective, but these studies show a way to trick the body’s own defenses into letting the drug in, demonstrating that this obstacle to treating Alzheimer’s could potentially be overcome.