Blogs / 80beats

It seems counterintuitive, because anesthetics are supposed to knock out patients and make them numb to all the jolts, jabs, and twinges of surgery. But a new study shows that many anesthetic drugs actually stimulate parts of the nervous system that sense pain, and can lead to increased discomfort after surgery.

Surgeons already knew that some knock-out drugs cause a burning sensation at the site of injection or in the lungs if the drug is inhaled, but the new research illuminates the mechanism of that response, and helps explain postoperative pain that was thought to be a result of the surgery exclusively. “Probably what is most significant for people to know is that this activation of a pain channel actually adds to post-surgery inflammation, so what we didn’t know before was that you could exacerbate swelling of surgery-damaged tissue with general anesthetics,” says Georgetown neuroscientist Gerard Ahern, who oversaw the new study [Science News].

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Gastric bypass surgery may seem a drastic option for someone battling obesity, but good results keep coming in: It works, and it appears to bring a host of health benefits. Last August, two studies showed that patients who tried the surgery had a reduced risk of dying from cancer; now a more specific study has demonstrated that the surgery cuts the risk of breast and colon cancer, the two most common forms.

Bariatric surgery is the only effective treatment for morbid obesity, according to the World Health Organization, and is usually performed using one of two different techniques. One focuses on reducing the size of the patient’s stomach alone, leading to decreased food intake. The second also reroutes food through the intestines, allowing fewer calories to be absorbed [Globe and Mail]. The surgery has already been shown to reduce risks of heart disease and diabetes, and the U.S. Medicare program is currently considering paying for the expensive surgery as a diabetes treatment.

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