FA=high-fat, ab libitum (eat-at-will) diet, FT=high-fat, time-restricted diet, NA=normal ab libitum (eat-at-will) diet, NT=normal diet, time-restricted
Diets tell you what you eat, but a new study suggests when you eat matters too. Of two groups of mice who were fed the same high-fat diet, the mice who could eat around the clock were much heavier than those who had food restricted to eight hours per day, in a new study published in Cell Metabolism.
Researchers in the study gave the mice a special high-fat chow, 61% of whose calories come from fat (compared to just 13% in normal feed). The mice who chowed down all day and night became, unsurprisingly, obese, but the ones who ate the same amount of hi-fat food in only eight hours per day did not. Their body weight was comparable to mice fed an equivalent amount of calories on normal feed.
What’s the News: Scientists—and smokers—have long known that nicotine is an appetite suppressant, but just how it kept hunger at bay remained unclear. Now, researchers have uncovered the neural pathway by which nicotine reduces appetite, in a study published today in Science. This discovery could lead to new drugs that help people quit smoking or lose weight.