Rose-thorn disease sounds like a malady of lovesick teenagers, an illness of romance reserved for budding Romeos and Juliets swooning from their first forays into passion and lovesickness, an affliction arising from the shocking stick and sting of heartbreak. The sweet name of this malady, however, in no way belies the actual crustiness of its symptoms.
Microbes are the omnipresent yet frequently unacknowledged adversary on the battlefield. Though microscopic in size, their very macroscopic effects can decimate armies, foil the best planned war initiatives, and change the course of history.
In the period October 1980-May 1981, 5 young men, all active homosexuals, were treated for biopsy-confirmed Pneumocystis carinii pneumonia at 3 different hospitals in Los Angeles, California. Two of the patients died. All 5 patients had laboratory-confirmed previous or current cytomegalovirus (CMV) infection and candidal mucosal infection. Case reports of these patients follow.
Last week, the State Department performed a small but smart gesture towards countering the continued outbreak of the Ebola virus in West Africa by releasing a video featuring President Barack Obama speaking to the people of Liberia, Sierra Leone, Guinea, and Nigeria.
This may come as a total shock, but pure forms of illicit drugs can be hard to come by. Certain controlled substances are frequently adulterated, if not outright contaminated, by products that range from the household to the industrial to the pharmaceutical. Of course, some substances are more easily, frequently, and profitably adulterated than others: cocaine purchased on the retail level is on average 31%, well, not cocaine, while the purity of heroin on the street is even lower, resting around 65% (1).
Unbeknownst to many of the public, August was National Immunization Awareness Month. I know, I know: it’s been overshadowed by some very exotic and thrilling headliners this month. The Ebola epidemic blazing defiantly in West Africa. The jaw-dropping videos shown on Discovery Channel’s “Shark Week.” The ALS Ice Bucket Challenge clogging everyone’s social feeds. Vaccines are just not as sexy or as flamboyant as these issues. Truthfully, they’re a bit dull to talk about, not a topic you would tend to bring up at cocktail parties or at the water cooler. Read More
Just as we jetsetters and nomads wander the wide world’s winding roads and byways by foot, on horseback, atop a bicycle or packed into an automobile, so too do infectious diseases make use of our ever-improving networks of thoroughfares. They ride along in human bodies, their journeys fueled by our social mobility and contact, two factors unavoidably intensified anytime we embark upon a voyage. But as these pathogens travel new routes and encounter new bodies, they can change and mutate. Luckily for researchers, by examining commonly traveled routes where we once naively believed that only humans trod, the active evolution and epidemiology of a pathogen can be revealed, providing insight into the development and patterns of disease affecting mankind.
In the twentieth century, men toiling in British and American coal mines relied on a primitive alert system for imperceptible dangers: the bright canary bird. Miners toted the caged birds into the depths of the earth to serve as early warnings against poisonous and potentially fatal gas leaks. If the tiny birds suddenly slumped in their cages due to the presence of odorless and colorless carbon monoxide, miners would beat a hasty retreat to safer, cleaner air.
Many pitfalls await the undergraduate in the laboratory. Bunsen burners! Liquid nitrogen! The slack work ethic of one’s peers! The dreaded group projects! But the most common risk budding researchers face are the rubber glove-donners themselves, perpetrator and victim rolled into one lab coat-wearing pipetter, armed and often dangerous with great knowledge but little know-how.
It’s one of the easiest ways to care for your health, a ritual we participate in daily: brushing those osseous outcroppings, our teeth. For those of us who heed the pleas of our dentists, flossing is a part of our routines, too. But the state of affairs of our glistening maws – the density of plaque, the presence of gingivitis, a full set of chompers – is important beyond mere aesthetics. Good oral fitness, particularly steps taken to limit the bacterial status quo, plays an important role in the goings-on of our body as a whole; a dirty mouth – and not the kind prone to sailor-like profanity – can provide important clues as to how susceptible you are to heart attacks and strokes.