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	<title>Comments on: Extremophilia</title>
	<link>http://blogs.discovermagazine.com/cosmicvariance/2006/01/25/extremophilia/</link>
	<description>Random samplings from a universe of ideas.</description>
	<pubDate>Sun, 05 Jul 2009 06:25:14 +0000</pubDate>
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		<title>By: D.radio</title>
		<link>http://blogs.discovermagazine.com/cosmicvariance/2006/01/25/extremophilia/#comment-10883</link>
		<dc:creator>D.radio</dc:creator>
		<pubDate>Thu, 11 May 2006 09:59:01 +0000</pubDate>
		<guid>http://blogs.discovermagazine.com/cosmicvariance/2006/01/25/extremophilia/#comment-10883</guid>
		<description>Anybody knows what time need Deinococcus for have their mitosis? and what type of grow table it have?
I'm a student of Biotechnology and I needed for a work.</description>
		<content:encoded><![CDATA[<p>Anybody knows what time need Deinococcus for have their mitosis? and what type of grow table it have?<br />
I&#8217;m a student of Biotechnology and I needed for a work.</p>
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		<title>By: Deinococcus</title>
		<link>http://blogs.discovermagazine.com/cosmicvariance/2006/01/25/extremophilia/#comment-10882</link>
		<dc:creator>Deinococcus</dc:creator>
		<pubDate>Tue, 21 Feb 2006 05:12:30 +0000</pubDate>
		<guid>http://blogs.discovermagazine.com/cosmicvariance/2006/01/25/extremophilia/#comment-10882</guid>
		<description>The debate about ALH84001 continues, but scientific consensus after a decade does not support the original paper published by McKay. That said, the decision by Science to publish the report was good since it forced the community to think carefully about the topic of biosignatures and what to look for in the future. Unfortunately, a Mars sample return mission seems very far away.</description>
		<content:encoded><![CDATA[<p>The debate about ALH84001 continues, but scientific consensus after a decade does not support the original paper published by McKay. That said, the decision by Science to publish the report was good since it forced the community to think carefully about the topic of biosignatures and what to look for in the future. Unfortunately, a Mars sample return mission seems very far away.</p>
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		<title>By: Plato</title>
		<link>http://blogs.discovermagazine.com/cosmicvariance/2006/01/25/extremophilia/#comment-10866</link>
		<dc:creator>Plato</dc:creator>
		<pubDate>Fri, 17 Feb 2006 05:38:03 +0000</pubDate>
		<guid>http://blogs.discovermagazine.com/cosmicvariance/2006/01/25/extremophilia/#comment-10866</guid>
		<description>&lt;b&gt;Probability 1&lt;/b&gt;, &lt;i&gt;by Amir D. Aczel, page 99&lt;/i&gt;,

&lt;blockquote&gt;In 1994 Allan Hills 84001 was handed over to David Mckay of Nasa's Johnson Space Center. Mckay asembled a nine-memebr team including scientists at NASA, Stanford University, the Universty of Georgia, and McGill University in Montreal. The team endeavored to determine whether there were any signs of life on the meteorite&lt;/blockquote&gt;

Well?</description>
		<content:encoded><![CDATA[<p><b>Probability 1</b>, <i>by Amir D. Aczel, page 99</i>,</p>
<blockquote><p>In 1994 Allan Hills 84001 was handed over to David Mckay of Nasa&#8217;s Johnson Space Center. Mckay asembled a nine-memebr team including scientists at NASA, Stanford University, the Universty of Georgia, and McGill University in Montreal. The team endeavored to determine whether there were any signs of life on the meteorite</p></blockquote>
<p>Well?</p>
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		<title>By: Deinococcus</title>
		<link>http://blogs.discovermagazine.com/cosmicvariance/2006/01/25/extremophilia/#comment-10881</link>
		<dc:creator>Deinococcus</dc:creator>
		<pubDate>Fri, 17 Feb 2006 00:31:30 +0000</pubDate>
		<guid>http://blogs.discovermagazine.com/cosmicvariance/2006/01/25/extremophilia/#comment-10881</guid>
		<description>For the latest on Deinococcus, see http://www.usuhs.mil/pat/deinococcus/index_20.htm.

Stay tuned for astrobiology-relevant work on radiation-driven microbial ecosystems and how manganese protects proteins, not DNA, during irradiation. Curious about what all of you are being taught on why ionizing radiation kills cells.

Mike</description>
		<content:encoded><![CDATA[<p>For the latest on Deinococcus, see <a href="http://www.usuhs.mil/pat/deinococcus/index_20.htm." rel="nofollow">http://www.usuhs.mil/pat/deinococcus/index_20.htm.</a></p>
<p>Stay tuned for astrobiology-relevant work on radiation-driven microbial ecosystems and how manganese protects proteins, not DNA, during irradiation. Curious about what all of you are being taught on why ionizing radiation kills cells.</p>
<p>Mike</p>
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		<title>By: Dumb Biologist</title>
		<link>http://blogs.discovermagazine.com/cosmicvariance/2006/01/25/extremophilia/#comment-10880</link>
		<dc:creator>Dumb Biologist</dc:creator>
		<pubDate>Fri, 27 Jan 2006 04:12:32 +0000</pubDate>
		<guid>http://blogs.discovermagazine.com/cosmicvariance/2006/01/25/extremophilia/#comment-10880</guid>
		<description>&lt;i&gt;P. aeroginosa&lt;/i&gt; can even grow in &lt;i&gt;distilled&lt;/i&gt; water, but if it was &lt;i&gt;sterilized&lt;/i&gt; water, it isn't aseptic any longer if something is growing in it.  Anway, the reason it can grow in distilled water is because even that has some traces of shmutz in it that microbes with very simple nutritional needs can thrive in (sort of).  Actually, I think most examples of the genus &lt;i&gt;Pseudomonas&lt;/i&gt; (maybe I should use "pseudomonads") do well in a huge range of conditions, and they're not picky eaters at all.</description>
		<content:encoded><![CDATA[<p><i>P. aeroginosa</i> can even grow in <i>distilled</i> water, but if it was <i>sterilized</i> water, it isn&#8217;t aseptic any longer if something is growing in it.  Anway, the reason it can grow in distilled water is because even that has some traces of shmutz in it that microbes with very simple nutritional needs can thrive in (sort of).  Actually, I think most examples of the genus <i>Pseudomonas</i> (maybe I should use &#8220;pseudomonads&#8221;) do well in a huge range of conditions, and they&#8217;re not picky eaters at all.</p>
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		<title>By: Paul Orwin</title>
		<link>http://blogs.discovermagazine.com/cosmicvariance/2006/01/25/extremophilia/#comment-10879</link>
		<dc:creator>Paul Orwin</dc:creator>
		<pubDate>Fri, 27 Jan 2006 03:57:53 +0000</pubDate>
		<guid>http://blogs.discovermagazine.com/cosmicvariance/2006/01/25/extremophilia/#comment-10879</guid>
		<description>Something I didn't expect to see at CV!  Some loose use of the word "sterile" over here.  I think you mean "sterilized".  Lots of things get sterilized, very few things are sterile (in the sense of abiotic).  Bacteria are remarkably good at being where they ought not to be (by our standards).  BTW, Deinococcus was recently found in the human stomach (a pretty extreme place as wellk, but apparently not as bad as we thought).</description>
		<content:encoded><![CDATA[<p>Something I didn&#8217;t expect to see at CV!  Some loose use of the word &#8220;sterile&#8221; over here.  I think you mean &#8220;sterilized&#8221;.  Lots of things get sterilized, very few things are sterile (in the sense of abiotic).  Bacteria are remarkably good at being where they ought not to be (by our standards).  BTW, Deinococcus was recently found in the human stomach (a pretty extreme place as wellk, but apparently not as bad as we thought).</p>
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		<title>By: Dumb Biologist</title>
		<link>http://blogs.discovermagazine.com/cosmicvariance/2006/01/25/extremophilia/#comment-10878</link>
		<dc:creator>Dumb Biologist</dc:creator>
		<pubDate>Fri, 27 Jan 2006 01:57:23 +0000</pubDate>
		<guid>http://blogs.discovermagazine.com/cosmicvariance/2006/01/25/extremophilia/#comment-10878</guid>
		<description>I don't know that much about &lt;i&gt;D. rad.&lt;/i&gt; molecular biology, but there's repair, and then there's repair+complete genomic redundancy at all times.  When bacteria suffer a lot of DNA damage (as I'm sure &lt;i&gt;D. rad.&lt;/i&gt; does in extreme environments), they typically resort to something called an "SOS response".  Repairing double-strand lesions requires replication of DNA, but when damage piles up too quickly for careful error-correction, the SOS response allows for quick-and-dirty replication that sacrifices accuracy for efficiency.  If bacteria constantly have to SOS, the mutations will pile up to lethal proportions.

I'm guessling &lt;i&gt;D. rad.&lt;/i&gt; can just say "Screw that, I got a handy, carefully synthesized extra copy right here.  And a few more where that came from."

That's a pretty good trick, to be able to carry around multiple extra genomes for repair whenever you need it, and cope with it all the while.  Look at what happens to us when we get even one extra chromosome.</description>
		<content:encoded><![CDATA[<p>I don&#8217;t know that much about <i>D. rad.</i> molecular biology, but there&#8217;s repair, and then there&#8217;s repair+complete genomic redundancy at all times.  When bacteria suffer a lot of DNA damage (as I&#8217;m sure <i>D. rad.</i> does in extreme environments), they typically resort to something called an &#8220;SOS response&#8221;.  Repairing double-strand lesions requires replication of DNA, but when damage piles up too quickly for careful error-correction, the SOS response allows for quick-and-dirty replication that sacrifices accuracy for efficiency.  If bacteria constantly have to SOS, the mutations will pile up to lethal proportions.</p>
<p>I&#8217;m guessling <i>D. rad.</i> can just say &#8220;Screw that, I got a handy, carefully synthesized extra copy right here.  And a few more where that came from.&#8221;</p>
<p>That&#8217;s a pretty good trick, to be able to carry around multiple extra genomes for repair whenever you need it, and cope with it all the while.  Look at what happens to us when we get even one extra chromosome.</p>
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		<title>By: Philip Downey</title>
		<link>http://blogs.discovermagazine.com/cosmicvariance/2006/01/25/extremophilia/#comment-10877</link>
		<dc:creator>Philip Downey</dc:creator>
		<pubDate>Thu, 26 Jan 2006 20:32:30 +0000</pubDate>
		<guid>http://blogs.discovermagazine.com/cosmicvariance/2006/01/25/extremophilia/#comment-10877</guid>
		<description>I didn't like that APOD very much, because they made the ability to repair DNA sound very exotic. Except for viruses, every organism can repair its DNA. Bacteria, us, and everything in between, can all do it.

Uncle Al: there's also Pseudomonas aeruginosa, which grows pretty much anywhere, even sterile water containers.</description>
		<content:encoded><![CDATA[<p>I didn&#8217;t like that APOD very much, because they made the ability to repair DNA sound very exotic. Except for viruses, every organism can repair its DNA. Bacteria, us, and everything in between, can all do it.</p>
<p>Uncle Al: there&#8217;s also Pseudomonas aeruginosa, which grows pretty much anywhere, even sterile water containers.</p>
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		<title>By: Sean</title>
		<link>http://blogs.discovermagazine.com/cosmicvariance/2006/01/25/extremophilia/#comment-10876</link>
		<dc:creator>Sean</dc:creator>
		<pubDate>Thu, 26 Jan 2006 20:21:11 +0000</pubDate>
		<guid>http://blogs.discovermagazine.com/cosmicvariance/2006/01/25/extremophilia/#comment-10876</guid>
		<description>I don't think that even &lt;em&gt;D. rad&lt;/em&gt; could survive if, say, the neutron were lighter than the proton, or the vacuum energy were at the Planck scale.  But I do agree that many anthropic arguments rely to heavily on extrapolations about our local forms of life.</description>
		<content:encoded><![CDATA[<p>I don&#8217;t think that even <em>D. rad</em> could survive if, say, the neutron were lighter than the proton, or the vacuum energy were at the Planck scale.  But I do agree that many anthropic arguments rely to heavily on extrapolations about our local forms of life.</p>
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		<title>By: Elliot</title>
		<link>http://blogs.discovermagazine.com/cosmicvariance/2006/01/25/extremophilia/#comment-10875</link>
		<dc:creator>Elliot</dc:creator>
		<pubDate>Thu, 26 Jan 2006 19:10:26 +0000</pubDate>
		<guid>http://blogs.discovermagazine.com/cosmicvariance/2006/01/25/extremophilia/#comment-10875</guid>
		<description>Doesn't the existence of more extreme forms of life tend to "relax" any anthropic constraints on fundamental parameters making the anthropic principle less predictive. In particular if complex information processing was "discovered" in a non-dna based/non-hydrocarbon environment it would seem to me that the Anthropeople would have some "splaning to do".

Elliot</description>
		<content:encoded><![CDATA[<p>Doesn&#8217;t the existence of more extreme forms of life tend to &#8220;relax&#8221; any anthropic constraints on fundamental parameters making the anthropic principle less predictive. In particular if complex information processing was &#8220;discovered&#8221; in a non-dna based/non-hydrocarbon environment it would seem to me that the Anthropeople would have some &#8220;splaning to do&#8221;.</p>
<p>Elliot</p>
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