Category: Mind & Brain

The Man Who Fought a Bull With Mind Control

By Jack El-Hai | March 21, 2016 11:42 am

Jose M.R. Delgado steps into a Spanish bullring as a bold demonstration of his research. (Credit: Yale University News Bureau)

The investigator, dressed incongruously in sweater and tie and holding a small metal box, stands in a bullring. He taunts a bull with a gesture of his hand. Suddenly the bull faces him and charges. Taking a couple of steps back, the investigator presses a button on the box to send a radio signal, and the bull halts in mid-stride. It turns away. The animal’s natural aggression has evaporated.

This risky behavior-control demonstration, conducted in Spain in 1963, was the signature experiment of José Manuel Rodríguez Delgado, a physiologist and scientific showman who explored the varied responses of the brain to electrical stimulation.

During the middle decades of the twentieth century, Delgado grew notorious for using electricity to elicit rage, anxiety, pleasure, drowsiness, and involuntary movements in his animal and human subjects. Critics complained that he was paving the way for mind control; Delgado countered that changing the functioning of brains through electrical stimulation was not necessarily a bad thing. Read More

CATEGORIZED UNDER: Mind & Brain, Top Posts

Is Seasonal Affective Disorder a Myth?

By Hugh Middleton, University of Nottingham | February 9, 2016 6:01 pm

(Credit: Stephen Harlan/Flickr)

A flurry of newspaper headlines have called into question the existence of SAD, or Seasonal Affective Disorder. Scientists, they reported, appear to have debunked a widespread conviction, that feeling low in winter time is a genuine illness caused by disturbed levels of brain chemicals and that demands treatment.

A visit to any number of Seasonal Affective Disorder (SAD) websites leads to online questionnaires offering “diagnosis”, treatment recommendations, and advertisements for light boxes – gadgets that simulate daylight and compensate for poor exposure to the real thing. SAD is identified as a form of depression caused by disturbances of hormonal rhythms sensitive to daylight, primarily melatonin. Unusually, intense exposure to artificial light often is advocated as a treatment. There is even a device that can be worn on the head, allowing the patient to use a light box on the move. Read More

CATEGORIZED UNDER: Mind & Brain, Top Posts

Nerve Stimulation Offers Hope for PTSD Sufferers

By Ben Thomas | February 3, 2016 11:02 am

Ron Ramirez, a retired Army sergeant is participating in the second phase study investigating the effectiveness of external trigeminal nerve stimulation for veterans with PTSD. Andrew Leuchter is conducting the research as at UCLA’s Semel Institute for Neuroscience and Human Behavior. (Credit: Reed Hutchinson/CalFoto/UCLA)

Millions of people are suffering from post-traumatic stress disorder (PTSD) right now. Among military personnel who’ve been deployed to Iraq and Afghanistan, an estimated 31 percent are PTSD sufferers. An estimated 52 percent of people with PTSD also suffer from major depressive disorder (MDD).

The cost of treating these disorders is estimated to run as high as $40 billion per year. The social consequences are harder to quantify, but many PTSD and MDD sufferers report marital problems, difficulties bonding with family and friends, and chronic suicidal thoughts.

But a team of researchers led by Andrew Leuchter, professor of psychiatry and biobehavioral sciences at UCLA, believes it has found a new treatment for PTSD and MDD. It’s not a new drug or a new form of psychotherapy. It’s a form of electronic nerve stimulation. Read More

MORE ABOUT: mental health

Fountain of Youth: The Secret Power of Friends and Family

By Jo Marchant | January 21, 2016 10:39 am

(Credit: Jacob Lund/Shutterstock)

The Nicoya peninsula in northwestern Costa Rica is one of the most beautiful places on the planet. This 75-mile sliver of land, just south of the Nicaraguan border, is covered with cattle pastures and tropical rain forests that stretch down to the crashing waves of the Pacific Ocean. The coastline is dotted with enclaves of expats who fill their time surfing, learning yoga and meditating on the beach.

For the locals, life is not so idyllic. They live in small, rural villages with limited access to basics such as electricity, linked by rough tracks that are dusty in the dry season and often impassable when it rains. The men earn a living by fishing and farming, or work as laborers or sabaneros (cowboys on huge cattle ranches), while the women cook on wood-burning stoves. Yet Nicoyans have a surprising claim to fame that is attracting the attention of scientists from around the world.

Their secret was uncovered in 2005 by Luis Rosero-Bixby, a demographer at the University of Costa Rica in San José. He used electoral records to work out how long Costa Ricans were living, and found that their life expectancy is surprisingly high. In general, people live longest in the world’s richest countries, where they have the most comfortable lives, the best health care and the lowest risk of infection. But that wasn’t the case here. Read More

Decision Hacks: The Neuroscience of Making Smarter Choices

By Ben Thomas | January 15, 2016 11:49 am

(Credit: Ollyy/Shutterstock)

Have you ever walked out of a store with a shiny new gadget and wondered, “Why did I buy this? I can’t afford it. I don’t need it. What made me buy it?” Maybe you’ve asked yourself similar questions after you broke your diet with a tempting dessert, or fell back into the arms of someone who broke your heart: “I knew I shouldn’t have done this. Why can’t I make smarter decisions?”

Neuroscientists have studied questions like these for decades, and they’ve produced a wealth of answers, as well as some tips to catch yourself in the midst of self-deception. Here are three simple ways to avoid deceiving yourself, and turn bad decisions into learning experiences. Read More

CATEGORIZED UNDER: Mind & Brain, Top Posts

Why We Snap: From Road Rage to Barroom Brawls

By Carl Engelking | January 13, 2016 2:03 pm

In LIFEMORTS, the “I” stands for the “Insult” trigger, which can easily provoke rage.

R. Douglas Fields, a neurobiologist in his 50s, won’t hesitate to lock a pickpocket into a deadly chokehold in the middle of the street. He’s done it before.

Fields isn’t a badass, crime-fighting martial artist whose cover is his day job in the lab — he’s just like everyone else. But when his wallet was snatched while traveling in Barcelona with his 17-year-old daughter in 2010, you could say he just, well, snapped. He didn’t have time to think. He jumped into action.


R. Douglas Fields

He got his wallet back.

That incident in Spain stuck with Fields, and it inspired his new book, Why We Snap: Understanding the Rage Circuit in Your Brain. Fields is a senior investigator at the National Institutes of Health in Maryland and the editor-in-chief of Neuron Glia Biology. He set out to understand the rage circuit and examined the latest research into human aggression.

Most violent behavior, Fields discovered, results from a clash between our evolutionary hardwiring and our modern world. To put it bluntly: Our rage circuit wasn’t designed for daily commutes on crowded highways or the deluge of social media affecting our relationships. Through his research, Fields outlines the nine primary triggers of the human rage circuit and puts them into the handy mnemonic LIFEMORTS: Life-or-death situation, Insult, Family, Environment, Mate, Order in society, Resources, Tribe and Stopped (being restrained or cornered).

Discover spoke with Fields about his investigation, and it turns out that our rage response is a complex double-edged sword that helps us and hurts us. You can listen to the interview below, or continue reading an edited version.

Discover: Snapping, or flipping out, is commonly seen as a negative response to a given situation. But in the book, you present a more agnostic view of this response. It’s both good — it’s essential for our survival — and bad. Can you explain the mechanisms that cause us to snap, and why they are both good and bad for us?

Fields: We call it snapping only when the outcome is inappropriate. But if you look inside the brain and look at the mechanisms that have been activated, it’s the same process that’s vital to responding quickly to any threatening situation. This mechanism isn’t in the cerebral cortex, it’s not conscious, because cortical thinking is too slow in a sudden, dangerous situation.

It involves neurocircuits of threat detection and sudden aggression. We need these circuits; we wouldn’t have them if we didn’t need them. That’s the double-edged sword of snapping.

What are the basic triggers for why we snap, and how did you narrow the myriad triggers that set people off into nine categories?  

F: It seems like anything can set off this response, but I took a different approach. Rather than taking a psychological approach, I took a neuroscience approach. I decided to look at the neural circuits in the brain that produce sudden aggression. What new research is showing is that there are different circuits for different kinds of triggers for sudden aggression. Of course, scientists use different names for these neural circuits, but much of communicating to the public is getting over the jargon.

For the purposes of communicating — but more importantly, for the purposes of understanding and controlling the aggressive snap responses — it was necessary to identify the triggers very quickly. I’ve taken these circuits of sudden aggression in the brain and separated them into nine triggers. I came up with the mnemonic LIFEMORTS because it’s chunked into your memory as life/death.

For example, what scientists would call maternal aggression, in LIFEMORTS that becomes “F” for “Family.” That’s how I did it, and that’s what’s unique. It’s based not on the behavior, but on the new neuroscience tracing out these circuits in the brain.

These are all independent circuits. In the past, people thought rage or fear all came from one part of the brain, and that’s just overly simplistic.


The Mate or Family trigger — violence used to protect family members or mates — appears to have sparked this altercation.

One of the most fascinating revelations from the book was the amount of information our brains process subconsciously. Can you talk a little about the work our brains are doing without our knowledge?

We think of conscious functions in the brain, but we don’t realize how much information processing is going on unconsciously. We can hold only a tiny fraction of the sensory information coming into our brains in our consciousness; most of this is going on unconsciously. We talk about this as trusting your gut.

Your amygdala gets sensory input from every one of your senses through a high-speed pathway reaching the threat-detection mechanism before it even goes to the cortex, where we have conscious awareness. That’s because your unconscious brain is surveying the world for threats. When it calculates that we’re in danger, it communicates that to the cortex with emotions like fear, anger or anxiety.

In general, people do not appreciate how much the brain is doing below the level of consciousness. You may not be able to put your finger on what’s wrong; If you suddenly just don’t feel right, you back off. Your brain is taking in enormous amounts of information and calculated there’s something wrong.

why-we-snapHow do our genes dictate the way we’ll respond to danger, or the sight of other people in danger?

F: Genes are a big part of it, as in everything in biology. It’s a mixture of genes, environment and chance. Different people will respond differently to the same situation. The genetic factors are those that affect this network of threat detection in the brain, which, by the way, spans from the frontal lobes all the way to the hypothalamus — it’s not a lizard brain.

We know many of these genes, and they are genes that affect the circuitry and production neurotransmitters like, for example, dopamine. That’s part of the reason why different people will have different reactions to the same threat.

How much of this can we actually control? Can we contain or channel our snaps to either stifle them in difficult situations, or direct that energy in a positive way? Is awareness of the triggers enough, or are we simply hostages to the hormones and firing synapses in our brains?

F: Most of the time, this mechanism works amazingly well. When we start talking about controlling the mechanism, we are talking about trying to prevent the misfires. Yes, I think that you can control it.

In fact, I’ve interviewed elite athletes, Secret Service agents and members of SEAL Team 6, and they control it. They have to. Understanding the mechanism helps to control it, but being able to identify why you are suddenly angry allows you then to disarm this response when it’s inappropriate.

Where does road rage fit into LIFEMORTS?

It turns out that road rage hits on all nine of them — little wonder. It’s a great one because we’re all familiar with rage on the highway, and it’s so bewildering.

These circuits in our brain evolved in our brain for a different world, a different time. In the modern world, many of these defensive triggers get tripped — inappropriately — by conditions that didn’t exist before. Driving is just full of them.

When somebody cuts in front of you, you suddenly find yourself overwhelmed with anger. But why? It really doesn’t make sense. If the purpose of driving is getting somewhere safely, a person in front of you or behind you will only make a few seconds’ difference. If you’re running in a field during a foot race and someone cuts in front of you, it wouldn’t evoke the same kind of anger, and you might even laugh. There’s something peculiar about the act of driving that causes this sudden anger.

One of the LIFEMORTS triggers is “E” for “Environment,” and that is to protect your home and property. Many mammals have this, and certainly humans do. It’s fundamental to our biology. When somebody cuts in front of you, we perceive that space in front of our car as our property. That trips this trigger that is designed to elicit sudden aggression to get into a physical battle with an intruder in your property. Once you can recognize why you are angry, rather than suppress it, suddenly it goes away. Suddenly it’s disarmed. It’s a misfire.


When someone tries to enter your home, it will trip the “E” trigger for “Environment.” Our brains are wired to respond forcefully when someone trespasses on our territory.

Q: How do seemingly normal, sane people suddenly become killers?

A: Every day we read about violence, murder and mayhem not caused by people who are mentally ill. It’s people who suddenly snap in rage, and in many cases — domestic disputes or barroom brawls — the person ends up snapping and murdering a person they are close to, even a loved one.

When I read about snapping in the newspaper, it’s left as a mystery because we don’t understand the backstory. There’s always a reason in these instances, and that information doesn’t get into the news story.

We all have the capability for violence. It’s wired into our brain over the struggle of evolution. We need it for protection. We needed it to kill animals. It doesn’t need to be taught. Unfortunately, it can be triggered inappropriately. One thing that is always behind this is a chronic stress that isn’t understood. Stress puts these triggers for violence on edge.

With 2016 being an election year, I have to ask: Do politicians, to a certain extent, manipulate the LIFEMORTS triggers for their benefit?

F: Two that we are seeing are the “Tribe” trigger and the “Environment” trigger. The “Tribe” trigger is that human beings will separate into groups, us versus them, and they will use violence to maintain those groups. In early times, strangers, or a strange group, was a threat. A lot of what we see going on in talks about refugees and how to handle borders are all examples of the “E” and “T” trigger.

You can define “us and them” in many terms, and we have to be careful in how we are manipulated into defining “them.” In any election, we should be aware when politicians are pushing on these triggers. The hopeful side is that these triggers will also unite us. When we saw that picture of the refugee whose family had been killed and washed up on the beach, everything changed. When we saw that man in the picture, we saw ourselves. We saw that he was part of our tribe. He may be a Syrian, but he was a father, a family man. He was us.


Image credits (excluding book cover and R. Douglas Fields): Everett Collection/Shutterstock

CATEGORIZED UNDER: Mind & Brain, Top Posts

Lucid Dreamers May Help Unravel the Mystery of Consciousness


(Credit: Hartwig HKD/Flickr)

We spend around six years of our lives dreaming – that’s 2,190 days or 52,560 hours. Although we can be aware of the perceptions and emotions we experience in our dreams, we are not conscious in the same way as when we’re awake. This explains why we can’t recognize that we’re in a dream and often mistake these bizarre narratives for reality.

But some people – lucid dreamers – have the ability to experience awareness during their dreams by “re-awakening” some aspects of their waking consciousness. They can even take control and act with intention in the dream world (think Leonardo DiCaprio in the film Inception). Read More

CATEGORIZED UNDER: Mind & Brain, Top Posts

The Limits of Fight-or-Flight Training

By Ben Thomas | January 5, 2016 11:30 am

(Credit: Adam Ziaja/Shutterstock)

The soldiers at Checkpoint 56 ordered the woman to stop.

She was Palestinian, the soldiers were Israeli, and this checkpoint divided the Israeli and Palestinian-controlled sections of Hebron on the West Bank. The checkpoint’s metal detector had gone off when the woman walked through. The soldiers ordered her to raise her veil. She refused.

Then she pulled a knife. Read More

CATEGORIZED UNDER: Mind & Brain, Top Posts

3 Implications of Memory-Boosting Devices

By Ben Thomas | December 22, 2015 3:18 pm

Scientists are only beginning to advance memory-enhancing technology research, but even in this early stage, there are questions that deserve consideration. (Illustration credit: Brian A Jackson/Shutterstock)

In fall, DARPA announced a major success in its Restoring Active Memory (RAM) program. Researchers implanted targeted electrical arrays in the brains of a few dozen volunteers — specifically in brain areas involved in memory.

The researchers found a way to read out neural “key codes” associated with specific memories, and then fed those codes back into the volunteers’ brains as they tried to recall lists of items or directions to places. While the results are still preliminary, DARPA claims that the RAM technique has already achieved “promising results” in improving memory retrieval.

Intriguing as this implant is, it’s only the latest in an ongoing series of neurological techniques and gizmos designed to boost and sharpen memory. The effects and implications of these systems raise questions that are worth consideration. Read More

CATEGORIZED UNDER: Mind & Brain, Technology, Top Posts

How Terrorist Attacks Influence Mental Health

By Daniel Antonius, The State University of New York | December 4, 2015 11:26 am

A growing body of research examines the psychological aftermath of terrorist attacks, such as the coordinated attacks in Paris on Nov. 13. (Credit: Stacey Newman /

On November 13 2015, a series of coordinated attacks in Paris left 130 people dead. A week later, armed gunmen stormed a hotel in Mali, seizing hostages while also firing indiscriminately at guests, killing 27 people. And this week a mass shooting in San Bernardino, California, left 14 dead. While the motive is not known, the FBI has assigned counterterrorism agents to the case, sparking public speculation that the shooting may have been an act of terrorism.

You could spend hours every day watching, reading and listening to news related to these events. This level of exposure can significantly influence your worldviews and how you live your life. Read More

CATEGORIZED UNDER: Mind & Brain, Top Posts
MORE ABOUT: psychology

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