The concept of being able to predict the sex of a baby during early pregnancy or even influence it by eating or doing certain things when trying to conceive has been the subject of public fascination and debate for many centuries. But surely the sex of a fetus is exclusively determined by the father’s sperm, carrying an X chromosome for girls and a Y chromosome for boys?
It turns out this is not the full story. Since the 17th century, it has been recognized that slightly more boys are born than girls. This is strange – if the sex were determined solely by chromosomes, the probability of either should be 50 percent and not variable. This must mean that, although the same number of boys and girls are conceived initially, more female fetuses than male ones are lost during the pregnancy. Read More
Most women experience some type of morning sickness during pregnancy, but some women develop a far more serious condition.
Hyperemesis gravidarum (HG), which causes severe nausea and vomiting during pregnancy, affects as many as 3 percent of pregnancies, leading to over 167,000 emergency department visits each year in the U.S.
And yet, the disease is neither well-understood nor well-known, even with the flurry of headlines when it was announced that the Duchess of Cambridge during her pregnancies suffered from the condition. Read More
There are multiple answers to the question of where we come from: early hominins, monkeys, primordial goo, or the Big Bang, to name a few. Today’s answer, though, has probably, just a split second ago, popped into many readers’ minds. Today’s answer is sexual intercourse, a.k.a. “bleeping.” So let’s go back to the beginning, hundreds of millions of years before we invented euphemisms and censorship, and let’s ask: How in the evolutionary world did sex begin?
Algae, the green gunk that runs amok in our fish tanks, as well as the seaweed that stinks up our summer beaches, include some of the simplest sexually reproducing organisms on Earth. These lineages go back nearly 2 billion years. Algae do it. Plants do it. Insects do it. Even fungi do it. Much of this sex involves releasing sperm into the wind or the water so they can be carried to nearby eggs (as in mosses), relying on a different species to carry male gametes to female ones (many flowers), or maneuvering two bodies so that the openings to the internal reproductive organs are close enough together for fluid exchange (most insects and most birds). Read More
There’s an idea circulating that humans are the only animal to experience sexual pleasure; that we approach sex in a way that is distinct from others. As with many questions about sex, this exposes some interesting facts about the way we discuss the subject.
On one level, the question of whether humans and nonhumans experience sex in the same way is fairly simply dismissed: how would we know? We cannot know how a nonhuman experiences anything – they can’t be asked. Sex as an experiential phenomenon for nonhumans is, quite simply, inaccessible. Science is obliged to propose questions that are answerable, and “how does a leopard slug experience sex?” is, at time of writing, about as unanswerable as they get.
Having said that, we can make educated guesses about whether sex is pleasurable for other species. Sex would be a very strange thing to seek if it didn’t bring some form of pleasure. It increases risk of disease, it wastes energy, it can seriously increase the likelihood of something bigger coming along and eating you (seriously, check out leopard-slug reproduction, below).
There is a good chance that your grandparents were born at home. I am going to go ahead and assume they turned out fine, or at least fine enough, since you were eventually born too and are now reading this.
But since the late 1960s, very few babies in the United States or the UK have been born outside of hospitals. As a result, you may find the new guidelines from the UK’s National Institutes for Health and Care Excellence (NICE) just as surprising as I did. For many healthy women, the NICE guidelines authors believe, there may be significant benefits to going back to the way things were.
Shortly after the NICE guidelines were issued, the New England Journal of Medicine invited me to write a response. The idea that any pregnant patient might be safer giving birth outside the hospital seemed heretical, at least to an American obstetrician like me. Knowing that no study or guideline is foolproof, I began my task by looking for holes to form a rebuttal.
I soon realized that this rebuttal largely hinged on flaws in the American system, not the British one. While we take excellent care of sick patients, we do less well for healthy patients with routine pregnancies – largely in the form of turning to medical interventions more than strictly necessary.
As the guidelines suggest, some women in the UK with low-risk pregnancies may be better off staying out of the hospital. Why? Because the significant risks of over-intervention in hospitals, such as unnecessary C-sections, may be far more likely (and therefore more dangerous) for patients than the risks of under-intervention at home or in birth centers. But women in the UK have access to greater range of settings where they can give birth. For women in much of the US, the choice is often the hospital or nothing.
A decade ago, a revolutionary paper showed that a hormone called oxytocin can actually make us trust other people. This spawned a flurry of research that revealed oxytocin’s potential to boost social interactions. Now a new study has shown that the hormone is actually very similar to alcohol, a well-known social lubricant. However, just like alcohol, it has a dark side.
In the first study, published in 2005, volunteers were asked to invest money in an anonymous trustee whose honesty could not be guaranteed. People who received a dose of oxytocin chose to invest more than those given a placebo – they were more trusting. Subsequent experiments have shown that oxytocin also leads people to become more empathetic, generous and cooperative. They become better at reading social nuances and facial expressions, believe others to be more approachable and become less fearful and anxious in social situations.
Not only this, it seems that oxytocin may help to promote fidelity. Evidence for this comes most clearly in two intensively studied and closely related rodent species. One, the prairie vole, is monogamous; mated couples form close pair bonds and share nest-building and parental duties. In the other, the meadow vole, males leave the female with the babies and will try to mate again.
The two species vary in their sensitivity to oxytocin. However, experiments that increase the effective sensitivity to oxytocin by increasing hormone dosage or blocking receptors in the brain can actually change pair-bonding behavior, making it easier for female prairie voles to choose a partner and turning previously promiscuous meadow vole males into monogamous, caring dads.
This article was originally published on The Conversation.
Popular wisdom and established evolutionary science hold that the sexes seek fundamentally different relationships: men want short-term, no-strings-attached relationships whereas women value longer-term, loyal partnerships.
The explanation generally comes down to biological differences between men and women. Because women invest more in reproduction than men do – think pregnancy, morning sickness and stretchmarks – being picky becomes important because choosing poorly can be costly, even devastating. However, for men, reproduction may only entail a brief sexual liaison and a bit of sperm – there are potentially no long-term costs. This calculus has been built into our psychology, many argue.
Think about it more carefully, though. Where do all the women sleeping with these guys come from? Shouldn’t it be difficult for men to find so many willing partners? As theorist Hanna Kokko noted, it takes two to tango.
If we go by the numbers, in a group with an equal number of both sexes, it is impossible, on average, for men to have more partners than women. So why do we expect male psychology to be so hellbent on one-night stands? And why, clearly in opposition to this notion, are many men often so devotedly paternal?
Here’s where an established body of literature in sociology and demography – called mating market theory (MMT) – can help out. According to MMT, relationship preferences are expected to follow not simply from these fixed biological propensities, but also to be heavily influenced by partner availability.
When Linda May went in to see her obstetrician during her first pregnancy, he told her she probably shouldn’t jump, run, or even walk. But May, an exercise physiologist who studies pregnant women and their babies, knew a thing or two about the positive ways that being active can help a mom-to-be’s health. Women who exercise with baby on board have been known to have, among other things, lower risks of gestational diabetes and pregnancy-induced high blood pressure than those who don’t.
Since then, May and other researchers have discovered even more ways that prenatal exercise benefits not only an expectant mother, but her growing baby, too—sometimes for years into the future—as attendees learned at last week’s Experimental Biology 2014 meeting in San Diego.
Decades ago, many more doctors gave similar advice to May’s obstetrician. Pregnancy was thought to be almost like an illness, a time when women needed to rest to protect themselves and their babies. In 1985, the American Congress of Obstetricians and Gynecologists came out with their first set of guidelines for exercise during pregnancy—guidelines, now considered conservative, that included suggestions like keeping strenuous activities to 15 minutes or less.
Since then, research has turned that idea on its head. Exercise is now thought to be—for most women with healthy pregnancies—a boon for the mother’s health, and for the baby she carries as well. Researchers are now starting to look even more closely at how exercise can influence a baby’s health in the womb and how these effects might translate into protection from future health problems.
Scientists have called the contraceptive pill one of the most important inventions of the twentieth century. Now, more than fifty years after the Pill was first released, contraception remains a woman’s world.
Sure, men can use condoms or have a vasectomy, but women have a much more dizzying array of options from which to choose. From pills to contraceptive vaginal rings to intrauterine devices and more, most scientists and pharmaceutical companies have focused their contraception efforts on women.
This isn’t necessarily a bad thing. Many reproductive health scientists say that we need more, not fewer, options for contraception. The problem is that virtually all contraception is being geared toward women. That’s largely because, historically, contraception was grouped in with the traditional female concerns of family and childbearing.
“There are a fair number of women who are dissatisfied with their current method of contraception,” said Michael O’Rand, a biologist and male contraception expert at the University of North Carolina at Chapel Hill.
Sophie Bushwick (Twitter, Tumblr) is a science journalist and podcaster, and is currently an intern at DISCOVERmagazine.com. She has written for Scientific American, io9, and DISCOVER, and has produced podcasts for 60-Second Science and Physics Central.
Human chromosomes (grey) capped by telomeres (white)
U.S. Department of Energy Human Genome Program
Renowned biologist Elizabeth Blackburn has said that when she was a young post-doc, “Telomeres just grabbed me and kept leading me on.” And lead her on they did—all the way to the Nobel Prize in Medicine in 2009. Telomeres are DNA sequences that continue to fascinate researchers and the public, partially because people with longer telomeres tend to live longer. So the recent finding that older men father offspring with unusually lengthy telomeres sounds like great news. Men of advanced age will give their children the gift of longer lives—right? But as is so often the case in biology, things aren’t that simple, and having an old father may not be an easy route to a long and healthy life.
Every time a piece of DNA gets copied, it can end up with errors in its sequence, or mutations. One of the most frequent changes is losing scraps of information from each end of the strand. Luckily, these strands are capped with telomeres, repeating sequences that do not code for any proteins and serve only to protect the rest of the DNA. Each time the DNA makes a copy, its telomeres get shorter, until these protective ends wear away to nothing. Without telomeres, the DNA cannot make any more copies, and the cell containing it will die.
But sperm are not subject to this telomere-shortening effect. In fact, the telomeres in sperm-producing stem cells not only resist degrading, they actually grow. This may be thanks to a high concentration of the telomere-repairing enzyme telomerase in the testicles; researchers are still uncertain. All they know is that the older the man, the longer the telomeres in his sperm will be.