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Discoblog
« Is That a Jet Landing by My Head, Or Just a Bat?
Female Spiders Attracted to Ultraviolet Bling »

Man’s Finger Heals Normally—No Eye of Newt or Bladder of Frog Required

magic.jpg

Last year, a story captured the hearts and imaginations of Harry Potter fans everywhere: Lee Spievack sliced off his fingertip (while showing a customer why the motor on his model plane was dangerous), and regrew it with magic pixie dust made from dried pigs’ bladder.

The real story, of course, did not involve magic. The powder, developed by his brother’s company, was composed of pig extracellular matrix—proteins that provide the scaffolding for cells and play a major role in wound healing—and was already in use for treating ulcers in people and to help horses repair torn ligaments. Nevertheless, the story got a fair bit of press at the time—which has, for some reason, been recently revived, with the inventor of the pixie dust voicing his hopes that the powder could one day be used to regrow bones and entire limbs.

But these newly emboldened dreams of limb regeneration using pig bladders are a huge stretch. Spievack’s injury really didn’t look that serious, and fingertips are notorious for growing back, anyways. It’s long been known that young children can regrow severed fingertips—including fingerprints, nails, sensations, and shape—more recently, this has been observed in adults. The best thing to do is simply clean the wound and cover it with some dressing.

And yesterday, a plastic surgeon called them out on it. Simon Kay, professor of hand surgery at the University of Leeds, said, “it’s a ridiculous story—absurd and over-egged in the extreme. It looked to have been an ordinary fingertip injury with quite unremarkable healing.”

Alas, pig bladder magic should not give you the confidence to chop off your fingertips on a whim—but, if you’re really in the mood, pure human biology does.

Image: Darks Adria/Flickr

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May 2nd, 2008 11:04 AM Tags: magic, regeneration
by Lizzie Buchen in Diseases, Injuries, & Other Ailments, The Wide (& Strange) World of Animals | 3 comments | RSS feed | Trackback >

  • larry

    you might want to review your blog post since your magazine just released a full-blown printed article on this technology documenting how pig-bladder was used to regenerate close to 70% of an US soldiers’ missing quadricep. I guess that was just simple human biology also right?

  • Amos Zeeberg (Discover Web Editor)

    You’re right, larry—ECM (extracellular matrix) treatment does now seem more promising than we originally thought. Here’s the article: How Pig Guts Became the Next Bright Hope for Regenerating Human Limbs.

  • http://www.moregoodstuff.info/how-pig-guts-became-the-next-bright-hope-for-regenerating-human-limbs How Pig Guts Became the Next Bright Hope for Regenerating Human Limbs | moregoodstuff.info

    [...] a plastic bag and reapply the powder every other day until his supply ran out. After four months, Lee’s fingertip had regenerated itself, nail, bone, and [...]





    • About the Blog

      Discoblog is DISCOVER's compendium of quirky, funny, and surprising science news from the edge of the known universe. It's written by Veronique Greenwood and Valerie Ross. Email tips and suggestions to vgreenwood [at] discovermagazine [dot] com.

      Discoblog also includes the daily feature NCBI ROFL, in which two prone-to-distraction grad students post real scientific articles with funny subjects. Email your tips to ncbirofl [at] gmail.com. Follow the ROFL feed here.

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