NCBI ROFL: Want your rat to get it on while high on ecstasy? Play loud music.

By ncbi rofl | July 23, 2009 4:45 pm

Effects on rat sexual behaviour of acute MDMA (ecstasy) alone or in combination with loud music.

“Surprisingly, one hour exposure to loud music, which per se resulted ineffective, antagonized the suppressive effect of MDMA by increasing the percent of animals displaying sexual activity. However, combined treatment of MDMA and music stimulation did not fully restore normal sexual behavior as the animals reaching ejaculation still showed a marked reduction of copulatory efficiency. These findings demonstrate that the systemic administration of a single low dose of MDMA, alone or in combination with loud music, which is commonly present in certain environments such as rave parties, notably impairs copulatory activity of male rats.”

Thanks to Sasha for today’s ROFL!

  • Anonymous

    So what does this tell us about youngsters taking ecstasy and going out to dance…? Do they go there to antagonize the drug effect?

    Also I miss a direct comparison of different music styles! (What about Bob Marley's "Rat Race" compared to the "Mighty Mouse Theme Song"?)

    Many questions and no answers in sight. :-(


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NCBI ROFL is the brainchild of two Molecular and Cell Biology graduate students at UC Berkeley and features real research articles from the PubMed database (which is housed by the National Center for Biotechnology information, aka NCBI) that they find amusing (ROFL is a commonly-used internet acronym for "rolling on the floor, laughing"). Follow us on twitter: @ncbirofl


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