NCBI ROFL: Binge drinking: also a problem for our teenage rats.

By ncbi rofl | August 17, 2009 5:09 pm

Intermittent access to beer promotes binge-like drinking in adolescent but not adult Wistar rats.

“We investigated the possibility of excessive adolescent drinking in a rodent model in which beer (4.44% ethanol vol/vol) is presented to adult and adolescent male Wistar rats… …Rats consumed an average of 7.8 g/kg/day of ethanol during adolescence (PND 34-55) and this gradually declined to a lower level of intake in adulthood (PND 56-93) of 3.9 g/kg/day. In Experiment 2, beer was made available to both adolescent (PND 29+) and adult (PND 57+) rats for 2h each day in a custom-built “lickometer” apparatus over 75 days. Access to beer was provided either 1 day out of every 3 (“intermittent” groups) or every day (“daily” groups). Relative to body weight, adolescent rats consumed more beer than adult rats in these limited access sessions. Adolescents with intermittent access consumed more than adolescents with daily access.”

CATEGORIZED UNDER: fun with animals, NCBI ROFL
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About ncbi rofl

NCBI ROFL is the brainchild of two Molecular and Cell Biology graduate students at UC Berkeley and features real research articles from the PubMed database (which is housed by the National Center for Biotechnology information, aka NCBI) that they find amusing (ROFL is a commonly-used internet acronym for "rolling on the floor, laughing"). Follow us on twitter: @ncbirofl

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