NCBI ROFL: Bad news: you have a tumor. Good news: it's really cute!

By ncbi rofl | April 21, 2010 7:00 pm
i1543-2165-128-9-1054-f01.jpeg
Pathologists must get bored staring at tumors all day, so they start imagining little friends in their samples.  There are numerous papers in PubMed highlighting their “discoveries” (or perhaps the results of self-imposed Rorschach tests?)Here are five of our favorites:

“A 46-year-old woman had an excisional breast biopsy that revealed nonproliferative fibrocystic changes as the only histopathologic abnormality. Although it was not Easter at the time of diagnosis, an Easter bunny was found hiding in one of the dilated ducts, which also contained amorphous eosinophilic secretions. A benign diagnosis in a breast biopsy (or any other biopsy) is good news for the patient at any time of the year, but even more special when accompanied by this little fellow.”

Images in pathology. Invasive squamous cell carcinoma of vulva that wanted to be a puppy.

“Squamous cell carcinomas of the vulva are usually well differentiated. Foci of invasion may be well circumscribed and show maturation (the head of the puppy). For such foci located close to the epidermis, diagnosis of invasion may pose a challenge. Careful examination and deeper levels may disclose clear cut foci of invasion. How many such foci can you find here?  For answer see below.”

335

“Answer:
At least 3:
Below the hind foot
In front of the neck
Above the tail”

Images in pathology. Even the bone smiles!

“Figure 1 shows an unusual bone finding from a 56-year-old woman’s biopsy. We encountered a “smiling” osseous trabecula; we do not know why it is so happy; nevertheless we want to share it with all fellow pathologists because a beautiful smile is always a beautiful smile!”

smiling_bone

Images in pathology: parotid bunny eating carrot.

364

Just look at that cute fluffy little tail!

Images in pathology: Snoopy in flight gear.

“Electron microscopy of a mesangial region from a glomerulus demonstrating an
interesting artifact.”

snoopy_flightgear

Related content:
Discoblog: NCBI ROFL: Two Cute: Research that would make grad school snugglier
Discoblog: NCBI ROFL: Viewing cute images increases behavioral carefulness
Discoblog: NCBI ROFL: Does pizza cause cancer?

WTF is NCBI ROFL? Read our FAQ!

  • Aquifex

    Probably the most awesome ROFL in recent times.

  • http://www.labgrab.com Labgrab

    the smiley face is just bizarre. I mean does it have to be so silly, as if to mock its victim?

  • http://www.samuraiscientist.blogspot.com Samurai Scientist

    hi quality

  • http://satcomguy.blogspot.com/ Satcomguy

    Actually, I thought the first picture reminded me more of Plankton from SpongeBob SquarePants!

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About ncbi rofl

NCBI ROFL is the brainchild of two Molecular and Cell Biology graduate students at UC Berkeley and features real research articles from the PubMed database (which is housed by the National Center for Biotechnology information, aka NCBI) that they find amusing (ROFL is a commonly-used internet acronym for "rolling on the floor, laughing"). Follow us on twitter: @ncbirofl

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