NCBI ROFL: Free-range maggots better for cleaning putrid wounds.

By ncbi rofl | November 15, 2010 7:00 pm

2281225633_3dd02bfb50Maggot debridement therapy: free-range or contained? An in-vivo study.

“OBJECTIVE: To determine which method of maggot debridement therapy–free-range or contained–is more effective for wound healing. METHODS: In vivo study of 64 patients with 69 chronic wounds that showed signs of gangrenous or necrotic tissue. Patients were treated with either free-range or contained maggot debridement therapy according to maggot availability, dressing difficulty, and physician preference. RESULTS: Significantly better outcomes were achieved with the free-range technique versus the contained technique (P = .028). With the free-range technique, the mean number of maggot applications and the total number of maggots per treatment were significantly lower than with the contained application technique (P = .028 and P < .001, respectively). CONCLUSION: This clinical in vivo study supports in vitro studies in which containment of maggots was found to reduce the effectiveness of maggot debridement therapy.”


Photo: flickr/gruntzooki

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WTF is NCBI ROFL? Read our FAQ!

  • Mark LaFlamme

    If the respect for these creatures keeps rising, army drill instructors will have to come up with better things to call recruits.

    Mark LaFlamme
    Author, “Box of Lies”

  • megan

    Contained and bred maggots are complacent and lazy. They don’t know a good thing to devour when it’s placed in front of them.


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NCBI ROFL is the brainchild of two Molecular and Cell Biology graduate students at UC Berkeley and features real research articles from the PubMed database (which is housed by the National Center for Biotechnology information, aka NCBI) that they find amusing (ROFL is a commonly-used internet acronym for "rolling on the floor, laughing"). Follow us on twitter: @ncbirofl


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