Blogs / Discoblog

Don’t take Viagra with grapefruit juice. Researchers have performed the first human-controlled study to show that when certain blood pressure, cancer, and antibiotic drugs are taken with fruit juices including grapefruit, orange, and apple, the drugs became “useless.”

Canadian researchers found that only half the allergy drug fexofenadine was absorbed when volunteers drank the pill with juice. A chemical in grapefruit juice called narigin blocked a key molecule that carries the drugs from the small intestines to the bloodstream, and therefore prevented the drug from going to the right targets. In oranges, the chemical to blame for blocking drugs is hesperidin. The researchers are still trying to figure out what chemical in apple juice causes the decrease in absorption.

“This is just the tip of the iceberg,” says David G. Bailey, a professor of clinical pharmacology at the University of Western Ontario. “I’m sure we’ll find more and more drugs that are affected this way.”

If you really are craving juice, then just leave some time before you take the medicine and drink it. Just remember that it’s best to take meds with water anyway.

Images: flickr/ Joshua Yospyn

The original seven deadly sins laid out by the Catholic Church—pride, envy, gluttony, greed, lust, wrath, and sloth—are the classics of immorality, the same basic flaws humans have evinced since coming out of the trees (and, perhaps, even before). But in our booming, globalized, highly networked world, there are some new and very harmful errors at our disposal. And while the Vatican doesn’t have a Facebook page yet (unlike Discover), they do recognize that modern times call for modern vices.

In an interview headlined “New Forms of Social Sin,” Gianfranco Girotti, head of the Vatican’s Apostolic Penitentiary, insisted that “new sins have appeared on the horizon of humanity as a corollary of the unstoppable process of globalization.” The list of “mortal sins,” as they have now been classified, came at the end of a week-long seminar in Rome that intended to deal with the dismal turnout at recent confessions. Seems logical: If a wider range of souls are in danger of eternal damnation, more will seek absolution. So, what are the new ways to fall from grace?

Girotti devotes some space to a familiar type of don’t-treat-your-brother-poorly admonitions—like social injustice that causes poverty or “the excessive accumulation of wealth by a few”—but many of the new rules concern modern science, stuff that the sixth-century pope Gregory the Great never dreamed of.

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