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	<title>Comments on: Beyond visualization of data in genetics</title>
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	<link>http://blogs.discovermagazine.com/gnxp/2010/05/beyond-visualization-of-data-in-genetics/</link>
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		<title>By: PCA plots and trees &#124; Gene Expression &#124; Discover Magazine</title>
		<link>http://blogs.discovermagazine.com/gnxp/2010/05/beyond-visualization-of-data-in-genetics/#comment-22245</link>
		<dc:creator>PCA plots and trees &#124; Gene Expression &#124; Discover Magazine</dc:creator>
		<pubDate>Tue, 01 Jun 2010 22:52:34 +0000</pubDate>
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		<description>[...] Blogs / Gene Expression        &#171; Beyond visualization of data in genetics [...] </description>
		<content:encoded><![CDATA[<p>[...] Blogs / Gene Expression        &laquo; Beyond visualization of data in genetics [...] </p>
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		<title>By: Razib Khan</title>
		<link>http://blogs.discovermagazine.com/gnxp/2010/05/beyond-visualization-of-data-in-genetics/#comment-22244</link>
		<dc:creator>Razib Khan</dc:creator>
		<pubDate>Tue, 01 Jun 2010 08:55:27 +0000</pubDate>
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		<description>&lt;i&gt;The purpose of this article appears to be an attempt to discount the value of these charts which contain some very important information.&lt;/i&gt;

no.</description>
		<content:encoded><![CDATA[<p><i>The purpose of this article appears to be an attempt to discount the value of these charts which contain some very important information.</i></p>
<p>no.</p>
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		<title>By: bioIgnoramus</title>
		<link>http://blogs.discovermagazine.com/gnxp/2010/05/beyond-visualization-of-data-in-genetics/#comment-22243</link>
		<dc:creator>bioIgnoramus</dc:creator>
		<pubDate>Tue, 01 Jun 2010 00:32:02 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/gnxp/?p=4331#comment-22243</guid>
		<description>&quot;Unlike physics biology can not rely too long on elegance, beauty, and formal clarity&quot;: aye, and physics tends to rely on them when there&#039;s a dearth of experimental data.</description>
		<content:encoded><![CDATA[<p>&#8220;Unlike physics biology can not rely too long on elegance, beauty, and formal clarity&#8221;: aye, and physics tends to rely on them when there&#8217;s a dearth of experimental data.</p>
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		<title>By: Peter Marsh</title>
		<link>http://blogs.discovermagazine.com/gnxp/2010/05/beyond-visualization-of-data-in-genetics/#comment-22242</link>
		<dc:creator>Peter Marsh</dc:creator>
		<pubDate>Mon, 31 May 2010 22:58:48 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/gnxp/?p=4331#comment-22242</guid>
		<description>The purpose of this article appears to be an attempt to discount the value of these charts which contain some very important information. Information that confirms previous studies regarding the origins of the Polynesians.

Here is an example of some of these studies linking America and Japan with Polynesia

InPeter Bellwoods book Mans Conquest of the Pacific he cites a study showing that
Polynesians and NW Coastal Indians have very similar blood. They both have No B, high A, high M, high R2 &amp; moderate Fya. The study showed Polynesians have no blood similarities to S.E. Asians or Melanesians.

S.W. Serjeantson “The Colonization of the Pacific – A Genetic Trail 1989 pp 135,162-163,166-7 &quot;The following genes set them apart: Polynesians lack HLA-B27 , wheras it is common amongst Melanesians.
HLA-Bw48 is commonly found in Polynesian populations, but occurs only sporadically in Melanesia. The only other known population with an appreciable frequency of   HLA-Bw48 is that of the North American Indians or more specifically the Tlingit. In Polynesia Bw48 co-occurs with A11, - suggesting a variation since Polynesians departed from the Canadian coast.

Theodore G Schurr and colleagues(1990) &#039;Both the North American Pima and the Central American Maya have high frequencies of the Mitochondrial DNA sequence variation containing the rare Asian RFLP Hine II morph 6 in conjunction with an Asian-specific 9 based pair deletion.&#039; It appears that both the Pima and the Maya are genetically very close to the Polynesians. The arrival of these genes in America is believed to have been between 6-8,000 years ago, ruling out the possibility of Polynesian origins as Polynesians have only been in the Pacific for 2,200 years. A migration of the Polynesians from America is far more logical.

Katsushi Tokunaga and colleagues. ‘Genetic link between Asians and Native Americans: Evidence from HLA genes and haplotypes&#039; in Human Immunology 62 1001-1008 (2001).
HLA24-Cw8-B48, A24-Cw10-B60 and A24-Cw9-B61 were all commonly observed in Taiwan indigenous populations, Tibetans, Thais, Japanese, Orochon in North East China, Buryat, Man,Yakut, Inuit, Tlingit, Pima, Maya and Maori.&#039;

Harihara and colleagues (1992) noted: When observing the ‘Frequency of a 9bp deletion in the mitochrondrial DNA among Asian populations&#039;. It appears that the Maori &amp; Cook Islanders had ancestors from the Shizuoka prefecture of Japan.&quot;

Fideas E, Leon S, and colleagues. &#039;HLA Trans Pacific contacts&#039;(1995) notes that; &#039;a tribe living near the Pacific Colombian coast named the Noanama/Wanana, are clustered genetically closer to Japanese people than to other American natives.Novick and colleagues concur with this.&#039;

Yes Polynesians are related to Japanese and native Taiwanese. They came vis the Kuroshio current to America and then sailed down to Hawaii - the Homeland of Polynesians. Yes they did mix with Caucasians - The Easter Islanders are paleolithic Caucasians from America - as are the Basques - hence their close genetic similarity.

In 1972 Professor Jean Dausset conducted a study of the Caucasian blue/green eyed, red heads of Easter Island, who are in fact a significant part of the Polynesian story. He found them to have an ancient strain of Caucasian blood, which can also be found in the Basques of Spain, characterised by A29 and B12. The analyses revealed that 39% of unrelated Basques and 37% of the Easter Islanders were carriers of the HLA gene B12. These were the highest and second highest proportions tested throughout the world. The figures for A29 were similar. The Easter Islanders, with 37%, had the highest proportion in the world, while the Basques were second with 24%. The most remarkable thing was; that the two genes were found as a haplotype (combined genetic markers) in 11% of Easter islanders and 7.9% of the Basques. No other people in the world had remotely comparable figures.&quot;
  In fact, from the above tests, the Easter Islanders appear to be of a more pure ancient Caucasian racial stock than the Basques!

So both these very visual graphs tell us exactly like it is.  Yes, there has been some recent genetic admixture, but geneticists can see that by looking at the gene tree where they can see the times of recombination.

Yes America WAS the stepping stone of Polynesians into the Pacific. The second graph in the above article shows this very clearly. This is the trail of Haplogroup B on the West coast of America which arrived 6-8,000 years ago, but in Polynesia its arrival was only 2,200 years ago. Chronology alone  suggests the direction of colonisation.

For more details regarding this alternative much more robust theory regarding the origins of the Polynesians see my website Polynesian Pathways at above url.</description>
		<content:encoded><![CDATA[<p>The purpose of this article appears to be an attempt to discount the value of these charts which contain some very important information. Information that confirms previous studies regarding the origins of the Polynesians.</p>
<p>Here is an example of some of these studies linking America and Japan with Polynesia</p>
<p>InPeter Bellwoods book Mans Conquest of the Pacific he cites a study showing that<br />
Polynesians and NW Coastal Indians have very similar blood. They both have No B, high A, high M, high R2 &amp; moderate Fya. The study showed Polynesians have no blood similarities to S.E. Asians or Melanesians.</p>
<p>S.W. Serjeantson “The Colonization of the Pacific – A Genetic Trail 1989 pp 135,162-163,166-7 &#8220;The following genes set them apart: Polynesians lack HLA-B27 , wheras it is common amongst Melanesians.<br />
HLA-Bw48 is commonly found in Polynesian populations, but occurs only sporadically in Melanesia. The only other known population with an appreciable frequency of   HLA-Bw48 is that of the North American Indians or more specifically the Tlingit. In Polynesia Bw48 co-occurs with A11, &#8211; suggesting a variation since Polynesians departed from the Canadian coast.</p>
<p>Theodore G Schurr and colleagues(1990) &#8216;Both the North American Pima and the Central American Maya have high frequencies of the Mitochondrial DNA sequence variation containing the rare Asian RFLP Hine II morph 6 in conjunction with an Asian-specific 9 based pair deletion.&#8217; It appears that both the Pima and the Maya are genetically very close to the Polynesians. The arrival of these genes in America is believed to have been between 6-8,000 years ago, ruling out the possibility of Polynesian origins as Polynesians have only been in the Pacific for 2,200 years. A migration of the Polynesians from America is far more logical.</p>
<p>Katsushi Tokunaga and colleagues. ‘Genetic link between Asians and Native Americans: Evidence from HLA genes and haplotypes&#8217; in Human Immunology 62 1001-1008 (2001).<br />
HLA24-Cw8-B48, A24-Cw10-B60 and A24-Cw9-B61 were all commonly observed in Taiwan indigenous populations, Tibetans, Thais, Japanese, Orochon in North East China, Buryat, Man,Yakut, Inuit, Tlingit, Pima, Maya and Maori.&#8217;</p>
<p>Harihara and colleagues (1992) noted: When observing the ‘Frequency of a 9bp deletion in the mitochrondrial DNA among Asian populations&#8217;. It appears that the Maori &amp; Cook Islanders had ancestors from the Shizuoka prefecture of Japan.&#8221;</p>
<p>Fideas E, Leon S, and colleagues. &#8216;HLA Trans Pacific contacts&#8217;(1995) notes that; &#8216;a tribe living near the Pacific Colombian coast named the Noanama/Wanana, are clustered genetically closer to Japanese people than to other American natives.Novick and colleagues concur with this.&#8217;</p>
<p>Yes Polynesians are related to Japanese and native Taiwanese. They came vis the Kuroshio current to America and then sailed down to Hawaii &#8211; the Homeland of Polynesians. Yes they did mix with Caucasians &#8211; The Easter Islanders are paleolithic Caucasians from America &#8211; as are the Basques &#8211; hence their close genetic similarity.</p>
<p>In 1972 Professor Jean Dausset conducted a study of the Caucasian blue/green eyed, red heads of Easter Island, who are in fact a significant part of the Polynesian story. He found them to have an ancient strain of Caucasian blood, which can also be found in the Basques of Spain, characterised by A29 and B12. The analyses revealed that 39% of unrelated Basques and 37% of the Easter Islanders were carriers of the HLA gene B12. These were the highest and second highest proportions tested throughout the world. The figures for A29 were similar. The Easter Islanders, with 37%, had the highest proportion in the world, while the Basques were second with 24%. The most remarkable thing was; that the two genes were found as a haplotype (combined genetic markers) in 11% of Easter islanders and 7.9% of the Basques. No other people in the world had remotely comparable figures.&#8221;<br />
  In fact, from the above tests, the Easter Islanders appear to be of a more pure ancient Caucasian racial stock than the Basques!</p>
<p>So both these very visual graphs tell us exactly like it is.  Yes, there has been some recent genetic admixture, but geneticists can see that by looking at the gene tree where they can see the times of recombination.</p>
<p>Yes America WAS the stepping stone of Polynesians into the Pacific. The second graph in the above article shows this very clearly. This is the trail of Haplogroup B on the West coast of America which arrived 6-8,000 years ago, but in Polynesia its arrival was only 2,200 years ago. Chronology alone  suggests the direction of colonisation.</p>
<p>For more details regarding this alternative much more robust theory regarding the origins of the Polynesians see my website Polynesian Pathways at above url.</p>
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		<title>By: Tweets that mention Beyond visualization of data in genetics &#124; Gene Expression &#124; Discover Magazine -- Topsy.com</title>
		<link>http://blogs.discovermagazine.com/gnxp/2010/05/beyond-visualization-of-data-in-genetics/#comment-22241</link>
		<dc:creator>Tweets that mention Beyond visualization of data in genetics &#124; Gene Expression &#124; Discover Magazine -- Topsy.com</dc:creator>
		<pubDate>Mon, 31 May 2010 15:33:00 +0000</pubDate>
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		<description>[...] This post was mentioned on Twitter by razib khan, Ron Simon and Jeff C. Coleman, J.S.. J.S. said: Beyond visualization of data in genetics http://ow.ly/17yZ0c [...] </description>
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