Comments on: Strange genetic variation in South Asia http://blogs.discovermagazine.com/gnxp/2010/08/strange-genetic-variation-in-south-asia/ Tue, 18 Jun 2013 22:42:00 +0000 hourly 1 http://wordpress.org/?v=3.4.2 By: Razib Khan http://blogs.discovermagazine.com/gnxp/2010/08/strange-genetic-variation-in-south-asia/#comment-23823 Razib Khan Mon, 09 Aug 2010 01:42:06 +0000 http://blogs.discovermagazine.com/gnxp/?p=5397#comment-23823 <i>Another possibility is Siddi admixture – after all Gujarat state is the main population center??</i> no. the makranis have african admixture, and it is obvious in them (they're more toward african than any other south asians). this doesn't show up on the plots with african populations. in fact, it doesn't show up with east asians either. i think it's something local to south asia, perhaps due to extreme inbreeding. Another possibility is Siddi admixture – after all Gujarat state is the main population center??

no. the makranis have african admixture, and it is obvious in them (they’re more toward african than any other south asians). this doesn’t show up on the plots with african populations. in fact, it doesn’t show up with east asians either. i think it’s something local to south asia, perhaps due to extreme inbreeding.

]]> By: pconroy http://blogs.discovermagazine.com/gnxp/2010/08/strange-genetic-variation-in-south-asia/#comment-23822 pconroy Mon, 09 Aug 2010 01:10:12 +0000 http://blogs.discovermagazine.com/gnxp/?p=5397#comment-23822 What if the mysterious group are admixed with Malays? I've always wondered where the settlers that arrived in Madagascar stopped off on the way. Another possibility is Siddi admixture - after all Gujarat state is the main population center?? What if the mysterious group are admixed with Malays? I’ve always wondered where the settlers that arrived in Madagascar stopped off on the way.

Another possibility is Siddi admixture – after all Gujarat state is the main population center??

]]> By: Razib Khan http://blogs.discovermagazine.com/gnxp/2010/08/strange-genetic-variation-in-south-asia/#comment-23821 Razib Khan Fri, 06 Aug 2010 20:05:29 +0000 http://blogs.discovermagazine.com/gnxp/?p=5397#comment-23821 scythians were iranian speaking. they should be alone the main axis, not orthogonal. the first figure has muslims and i think a parsi or two who are probably good substitutes for iranians. so perhaps huns with mongolian ancestry? but that doesn't show up on structure which infer ancestry components (in fact, northeast indians have that). two thoughts 1) this only shows up when you constrain the variation which you're using to extract dimensionalities. so it's something weird specific to south asia i think, and interpreting the PCA in a global context may mislead 2) the kalash are really strange in their positioning in south asia because they've very inbred/genetically isolated. it could be the admixture of some group like this in the north/west of india, who arrived with the sakas, etc. scythians were iranian speaking. they should be alone the main axis, not orthogonal. the first figure has muslims and i think a parsi or two who are probably good substitutes for iranians. so perhaps huns with mongolian ancestry? but that doesn’t show up on structure which infer ancestry components (in fact, northeast indians have that).

two thoughts

1) this only shows up when you constrain the variation which you’re using to extract dimensionalities. so it’s something weird specific to south asia i think, and interpreting the PCA in a global context may mislead

2) the kalash are really strange in their positioning in south asia because they’ve very inbred/genetically isolated. it could be the admixture of some group like this in the north/west of india, who arrived with the sakas, etc.

]]> By: Thorfinn http://blogs.discovermagazine.com/gnxp/2010/08/strange-genetic-variation-in-south-asia/#comment-23820 Thorfinn Fri, 06 Aug 2010 19:53:39 +0000 http://blogs.discovermagazine.com/gnxp/?p=5397#comment-23820 What about a Saka/Scythian origin? That would explain why they are concentrated in North/Western groups, and lie orthogonal to the main axis. Reich's speculation--that they are Huns--also seems reasonable. What about a Saka/Scythian origin? That would explain why they are concentrated in North/Western groups, and lie orthogonal to the main axis. Reich’s speculation–that they are Huns–also seems reasonable.

]]> By: Tweets that mention Strange genetic variation in South Asia | Gene Expression | Discover Magazine -- Topsy.com http://blogs.discovermagazine.com/gnxp/2010/08/strange-genetic-variation-in-south-asia/#comment-23819 Tweets that mention Strange genetic variation in South Asia | Gene Expression | Discover Magazine -- Topsy.com Fri, 06 Aug 2010 09:14:07 +0000 http://blogs.discovermagazine.com/gnxp/?p=5397#comment-23819 [...] This post was mentioned on Twitter by razib khan, Maggie, Sains & Teknologi, Al Poe, World Amazing Things and others. World Amazing Things said: Strange genetic variation in South Asia | Gene Expression: Dienekes has a post up where he highlights the fact tha... http://bit.ly/bQTf1O [...] [...] This post was mentioned on Twitter by razib khan, Maggie, Sains & Teknologi, Al Poe, World Amazing Things and others. World Amazing Things said: Strange genetic variation in South Asia | Gene Expression: Dienekes has a post up where he highlights the fact tha… http://bit.ly/bQTf1O [...]

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