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	<title>Comments on: The paradigm is dead, long live the paradigm!</title>
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	<link>http://blogs.discovermagazine.com/gnxp/2010/12/the-paradigm-is-dead-long-live-the-paradigm/</link>
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		<title>By: Alvah Hicks</title>
		<link>http://blogs.discovermagazine.com/gnxp/2010/12/the-paradigm-is-dead-long-live-the-paradigm/#comment-29432</link>
		<dc:creator>Alvah Hicks</dc:creator>
		<pubDate>Thu, 30 Dec 2010 09:12:17 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/gnxp/?p=8613#comment-29432</guid>
		<description>Thank you Razib and your Bloggers for another year of fine insights. Looking forward to 2011!</description>
		<content:encoded><![CDATA[<p>Thank you Razib and your Bloggers for another year of fine insights. Looking forward to 2011!</p>
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		<title>By: Beware of British newspapers: fossils edition &#124; Gene Expression &#124; Discover Magazine</title>
		<link>http://blogs.discovermagazine.com/gnxp/2010/12/the-paradigm-is-dead-long-live-the-paradigm/#comment-29431</link>
		<dc:creator>Beware of British newspapers: fossils edition &#124; Gene Expression &#124; Discover Magazine</dc:creator>
		<pubDate>Wed, 29 Dec 2010 06:32:22 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/gnxp/?p=8613#comment-29431</guid>
		<description>[...] in the Holy Land! More broadly I think the recent changes in our understanding of human origins over the past year have unsettled the field enough that sensationalists have an excellent opportunity to populate the [...] </description>
		<content:encoded><![CDATA[<p>[...] in the Holy Land! More broadly I think the recent changes in our understanding of human origins over the past year have unsettled the field enough that sensationalists have an excellent opportunity to populate the [...] </p>
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		<title>By: Warren Dew</title>
		<link>http://blogs.discovermagazine.com/gnxp/2010/12/the-paradigm-is-dead-long-live-the-paradigm/#comment-29430</link>
		<dc:creator>Warren Dew</dc:creator>
		<pubDate>Tue, 28 Dec 2010 19:20:46 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/gnxp/?p=8613#comment-29430</guid>
		<description>German, thanks for the reference.  It seems to me Hammer&#039;s Y chromosome paper does still confirm coalescence in Africa around 200 kya, similar to mitochondrial coalescence data.  I do agree that the bidirectional gene flow that he found did suggest that idea of an earlier unidirectional replacement expansion out of Africa might be suspect.  The ~70% replacement of Y chromosomes in Africa from an Asian root in a much shorter period of time does look like it could eventually have resulted in a complete replacement that would have masked more complex underlying population genetics, suggesting the same might apply to the 200 kya coalescences, but it&#039;s not clear to me that that implication ought to have been obvious to everyone.

Miko, the modern civil rights liberals in my social circles seem to see equality of results, not equality of opportunity, as the goal; unequal results due to unequal diligence or unequal talent seems anathema to them.  That&#039;s what I would mean by &quot;egalitarianism&quot;, though its actual philosophical roots seem to trace only to Rawls.</description>
		<content:encoded><![CDATA[<p>German, thanks for the reference.  It seems to me Hammer&#8217;s Y chromosome paper does still confirm coalescence in Africa around 200 kya, similar to mitochondrial coalescence data.  I do agree that the bidirectional gene flow that he found did suggest that idea of an earlier unidirectional replacement expansion out of Africa might be suspect.  The ~70% replacement of Y chromosomes in Africa from an Asian root in a much shorter period of time does look like it could eventually have resulted in a complete replacement that would have masked more complex underlying population genetics, suggesting the same might apply to the 200 kya coalescences, but it&#8217;s not clear to me that that implication ought to have been obvious to everyone.</p>
<p>Miko, the modern civil rights liberals in my social circles seem to see equality of results, not equality of opportunity, as the goal; unequal results due to unequal diligence or unequal talent seems anathema to them.  That&#8217;s what I would mean by &#8220;egalitarianism&#8221;, though its actual philosophical roots seem to trace only to Rawls.</p>
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		<title>By: Stiofan</title>
		<link>http://blogs.discovermagazine.com/gnxp/2010/12/the-paradigm-is-dead-long-live-the-paradigm/#comment-29429</link>
		<dc:creator>Stiofan</dc:creator>
		<pubDate>Tue, 28 Dec 2010 18:58:06 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/gnxp/?p=8613#comment-29429</guid>
		<description>Razib:

There are threads on Neanderthal and Denisovan SNPs at 23andme.com.  Comparing my self to the 5 SNPs 23andme recognizes from the Denisovans I get the following results:

My results at the 4 v.2 tested SNPs:

rs17324735  (C or T)   CT   chr 9    results  AFR 0/46 CEU 4/44 ASN 0/48
rs10971319  (A or G)  AG   chr 9    results  AFR 0/46 CEU 4/44 ASN 0/48
rs1148274    (G or T)   TT    chr 10 results  AFR 0/46 CEU 8/40 ASN 0/48
rs2241970    (A or G)  AG   chr 10  results  AFR 46/0 CEU 38/10 ASN 39/9

The last seems so wide spread as to not be a reliable marker for Denisovan ancestry and to indicate a marker from before the split.

rs17226291 is recognized as a SNP but says &quot;Not Tested&quot; in my results

Hopefully the Denisovan SNPs,  the Neaqnderthal SNPs, and the archaic Asian(?) SNPs Hammer found, can be placed on a chip so we can compare to them.

Thanks for your article and blog.</description>
		<content:encoded><![CDATA[<p>Razib:</p>
<p>There are threads on Neanderthal and Denisovan SNPs at 23andme.com.  Comparing my self to the 5 SNPs 23andme recognizes from the Denisovans I get the following results:</p>
<p>My results at the 4 v.2 tested SNPs:</p>
<p>rs17324735  (C or T)   CT   chr 9    results  AFR 0/46 CEU 4/44 ASN 0/48<br />
rs10971319  (A or G)  AG   chr 9    results  AFR 0/46 CEU 4/44 ASN 0/48<br />
rs1148274    (G or T)   TT    chr 10 results  AFR 0/46 CEU 8/40 ASN 0/48<br />
rs2241970    (A or G)  AG   chr 10  results  AFR 46/0 CEU 38/10 ASN 39/9</p>
<p>The last seems so wide spread as to not be a reliable marker for Denisovan ancestry and to indicate a marker from before the split.</p>
<p>rs17226291 is recognized as a SNP but says &#8220;Not Tested&#8221; in my results</p>
<p>Hopefully the Denisovan SNPs,  the Neaqnderthal SNPs, and the archaic Asian(?) SNPs Hammer found, can be placed on a chip so we can compare to them.</p>
<p>Thanks for your article and blog.</p>
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		<title>By: miko</title>
		<link>http://blogs.discovermagazine.com/gnxp/2010/12/the-paradigm-is-dead-long-live-the-paradigm/#comment-29428</link>
		<dc:creator>miko</dc:creator>
		<pubDate>Mon, 27 Dec 2010 21:26:38 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/gnxp/?p=8613#comment-29428</guid>
		<description>&quot;default position held in polite society&quot;

Maybe, but I feel like most civil rights liberals explicitly see equality as a rule of law issue or equal protection entitlement and are understandably suspicious of biological bases for anything political. That said, when a prominent biologist like Gould emits handy sound bites they are happy to selectively include biology. Dennet--raving liberal that he is--is good on the general misinformed-ness created among non-scientist intellectuals by Gould.</description>
		<content:encoded><![CDATA[<p>&#8220;default position held in polite society&#8221;</p>
<p>Maybe, but I feel like most civil rights liberals explicitly see equality as a rule of law issue or equal protection entitlement and are understandably suspicious of biological bases for anything political. That said, when a prominent biologist like Gould emits handy sound bites they are happy to selectively include biology. Dennet&#8211;raving liberal that he is&#8211;is good on the general misinformed-ness created among non-scientist intellectuals by Gould.</p>
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		<title>By: Razib Khan</title>
		<link>http://blogs.discovermagazine.com/gnxp/2010/12/the-paradigm-is-dead-long-live-the-paradigm/#comment-29427</link>
		<dc:creator>Razib Khan</dc:creator>
		<pubDate>Mon, 27 Dec 2010 21:08:59 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/gnxp/?p=8613#comment-29427</guid>
		<description>if i read gould correct it seems he&#039;s trying to buttress ought through is, but, he isn&#039;t going to explicitly do it because he is aware that science can change. on a related note, cannibalism, genocide, etc., happened between very closely related groups genetically until the rise of agriculture. also he seems to have elaborated on this issue in his huge last mega-book, when out of africa had really cleared the field (he also caricatures multiregionalism).

in any case, as paul krugman noted in the USA sj gould was the evolutionary biologist par excellence in the public eye. so his confused and convoluted musings held great weight, and from what i can tell his readers did connect the dots that recent human ancestry refuted human equality in some ethical sense.

 &#039;biological egalitarianism&#039; is probably used by detractors precisely because it is in some sense a default position held in polite society. the converse of the mainstream position in the west between 1850 and sometime in the early-mid-20th century.</description>
		<content:encoded><![CDATA[<p>if i read gould correct it seems he&#8217;s trying to buttress ought through is, but, he isn&#8217;t going to explicitly do it because he is aware that science can change. on a related note, cannibalism, genocide, etc., happened between very closely related groups genetically until the rise of agriculture. also he seems to have elaborated on this issue in his huge last mega-book, when out of africa had really cleared the field (he also caricatures multiregionalism).</p>
<p>in any case, as paul krugman noted in the USA sj gould was the evolutionary biologist par excellence in the public eye. so his confused and convoluted musings held great weight, and from what i can tell his readers did connect the dots that recent human ancestry refuted human equality in some ethical sense.</p>
<p> &#8216;biological egalitarianism&#8217; is probably used by detractors precisely because it is in some sense a default position held in polite society. the converse of the mainstream position in the west between 1850 and sometime in the early-mid-20th century.</p>
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		<title>By: miko</title>
		<link>http://blogs.discovermagazine.com/gnxp/2010/12/the-paradigm-is-dead-long-live-the-paradigm/#comment-29426</link>
		<dc:creator>miko</dc:creator>
		<pubDate>Mon, 27 Dec 2010 21:01:24 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/gnxp/?p=8613#comment-29426</guid>
		<description>&quot;Human equality is a contingent fact of history. Equality is not given a priori; it is neither an ethical principle (though equal treatment may be) nor a statement about norms of social action.&quot;

Ha!  You know I won&#039;t defend the master confuser...I have no idea what he could mean by &quot;equality&quot;  if not an ethical principle or the same thing as equal treatment.</description>
		<content:encoded><![CDATA[<p>&#8220;Human equality is a contingent fact of history. Equality is not given a priori; it is neither an ethical principle (though equal treatment may be) nor a statement about norms of social action.&#8221;</p>
<p>Ha!  You know I won&#8217;t defend the master confuser&#8230;I have no idea what he could mean by &#8220;equality&#8221;  if not an ethical principle or the same thing as equal treatment.</p>
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		<title>By: Razib Khan</title>
		<link>http://blogs.discovermagazine.com/gnxp/2010/12/the-paradigm-is-dead-long-live-the-paradigm/#comment-29425</link>
		<dc:creator>Razib Khan</dc:creator>
		<pubDate>Mon, 27 Dec 2010 20:42:54 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/gnxp/?p=8613#comment-29425</guid>
		<description>you can reread gould&#039;s old essay about human equality being a contingent fact of history. i don&#039;t know what he was really getting at at this point after rereading it

http://www.scribd.com/doc/18185121/Human-Equality-Is-a-Contingent-Fact-of-History</description>
		<content:encoded><![CDATA[<p>you can reread gould&#8217;s old essay about human equality being a contingent fact of history. i don&#8217;t know what he was really getting at at this point after rereading it</p>
<p><a href="http://www.scribd.com/doc/18185121/Human-Equality-Is-a-Contingent-Fact-of-History" rel="nofollow">http://www.scribd.com/doc/18185121/Human-Equality-Is-a-Contingent-Fact-of-History</a></p>
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		<title>By: miko</title>
		<link>http://blogs.discovermagazine.com/gnxp/2010/12/the-paradigm-is-dead-long-live-the-paradigm/#comment-29424</link>
		<dc:creator>miko</dc:creator>
		<pubDate>Mon, 27 Dec 2010 20:24:50 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/gnxp/?p=8613#comment-29424</guid>
		<description>@cyrax:  so because some people don&#039;t know what egalitarianism means, you are free to misuse it as well? just because homeopaths call the water they sell &quot;alternative medicine&quot; doesn&#039;t mean thinking people have to include it in their conception of &quot;medicine&quot; or refer to it as such. but, i took your advice and used the google and discovered that &quot;biological egalitarianism&quot; is a term used almost solely by its detractors to caricature something or other...i got bored pretty fast. i am unaware of anyone who has ever advanced an argument for an egalitarian society based on the claim that humans lack genetic--or any other kind of--diversity. if so, they sound pretty fringe and probably not in a position to provoke such self-righteous outrage. as for social policies, you must be the first person to notice that in the service of political goals sometimes people stray from ideological purity. thank goodness, because then the states-rights-lovers on the supreme court couldn&#039;t have installed gw, right?

words lose meaning in the mouths of ideologues, but the discourse here is normally somewhat elevated above such nonsense. your rant was so typical of paranoid noisemakers that i found it difficult to tell if it was genuine, and your baseless assertion about the cognitive effects of archaic genetic admixture (and calling it &quot;parsimonious&quot;) was such a crystalline example of ideological dumbing down of three or four branches of the life sciences at once, i felt it warranted comment.</description>
		<content:encoded><![CDATA[<p>@cyrax:  so because some people don&#8217;t know what egalitarianism means, you are free to misuse it as well? just because homeopaths call the water they sell &#8220;alternative medicine&#8221; doesn&#8217;t mean thinking people have to include it in their conception of &#8220;medicine&#8221; or refer to it as such. but, i took your advice and used the google and discovered that &#8220;biological egalitarianism&#8221; is a term used almost solely by its detractors to caricature something or other&#8230;i got bored pretty fast. i am unaware of anyone who has ever advanced an argument for an egalitarian society based on the claim that humans lack genetic&#8211;or any other kind of&#8211;diversity. if so, they sound pretty fringe and probably not in a position to provoke such self-righteous outrage. as for social policies, you must be the first person to notice that in the service of political goals sometimes people stray from ideological purity. thank goodness, because then the states-rights-lovers on the supreme court couldn&#8217;t have installed gw, right?</p>
<p>words lose meaning in the mouths of ideologues, but the discourse here is normally somewhat elevated above such nonsense. your rant was so typical of paranoid noisemakers that i found it difficult to tell if it was genuine, and your baseless assertion about the cognitive effects of archaic genetic admixture (and calling it &#8220;parsimonious&#8221;) was such a crystalline example of ideological dumbing down of three or four branches of the life sciences at once, i felt it warranted comment.</p>
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		<title>By: ohwilleke</title>
		<link>http://blogs.discovermagazine.com/gnxp/2010/12/the-paradigm-is-dead-long-live-the-paradigm/#comment-29423</link>
		<dc:creator>ohwilleke</dc:creator>
		<pubDate>Mon, 27 Dec 2010 08:20:17 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/gnxp/?p=8613#comment-29423</guid>
		<description>&quot;yet a generation of mtDNA and NRY studies have seemingly missed this.&quot;

It isn&#039;t hard to come up with multiple models with fairly weak assumptions that eliminate mtDNA and NRY traces while preserving autosomal DNA in low frequencies, and the models that achieve that result for Neanderthal admixture work just as well for the Denisovians.</description>
		<content:encoded><![CDATA[<p>&#8220;yet a generation of mtDNA and NRY studies have seemingly missed this.&#8221;</p>
<p>It isn&#8217;t hard to come up with multiple models with fairly weak assumptions that eliminate mtDNA and NRY traces while preserving autosomal DNA in low frequencies, and the models that achieve that result for Neanderthal admixture work just as well for the Denisovians.</p>
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		<title>By: German Dziebel</title>
		<link>http://blogs.discovermagazine.com/gnxp/2010/12/the-paradigm-is-dead-long-live-the-paradigm/#comment-29422</link>
		<dc:creator>German Dziebel</dc:creator>
		<pubDate>Mon, 27 Dec 2010 04:48:04 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/gnxp/?p=8613#comment-29422</guid>
		<description>Warren,

Ever since the publication by Hammer et al. (the same Hammer as you mentioned in conjunction with a 2 MYA coalescence in East Asia) of &quot;Out of Africa and Back again&quot; (mbe.oxfordjournals.org/cgi/reprint/15/4/427.pdf), there&#039;s been a recurrent argument that the majority of African Y chromosomes (the huge pan-African E clade characterized by YAP+) are in fact derived from Asia. This would mean that immediately before the founding migration of the would-be E lineages to Sub-Saharan Africa (roughly at 40-45K YBP)  there were two big clusters of Y-DNA diversity in the world - the African one, or the AB cluster, and the extra-African one - most likely East Asian, which encompassed CF and pre-DE lineages.</description>
		<content:encoded><![CDATA[<p>Warren,</p>
<p>Ever since the publication by Hammer et al. (the same Hammer as you mentioned in conjunction with a 2 MYA coalescence in East Asia) of &#8220;Out of Africa and Back again&#8221; (mbe.oxfordjournals.org/cgi/reprint/15/4/427.pdf), there&#8217;s been a recurrent argument that the majority of African Y chromosomes (the huge pan-African E clade characterized by YAP+) are in fact derived from Asia. This would mean that immediately before the founding migration of the would-be E lineages to Sub-Saharan Africa (roughly at 40-45K YBP)  there were two big clusters of Y-DNA diversity in the world &#8211; the African one, or the AB cluster, and the extra-African one &#8211; most likely East Asian, which encompassed CF and pre-DE lineages.</p>
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		<title>By: Warren Dew</title>
		<link>http://blogs.discovermagazine.com/gnxp/2010/12/the-paradigm-is-dead-long-live-the-paradigm/#comment-29421</link>
		<dc:creator>Warren Dew</dc:creator>
		<pubDate>Mon, 27 Dec 2010 02:55:19 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/gnxp/?p=8613#comment-29421</guid>
		<description>German, I&#039;m not sure I understand what you&#039;re saying.  For Y chromosome coalescence to have happened outside of Africa, all Y chromosome lineages in Africa would have to be derived from outside Africa, not just a majority.  Is that your contention?  My understanding is that Africa was still the likely location of Y chromosome coalescence, but I confess to not having followed the Y chromosome literature very carefully.</description>
		<content:encoded><![CDATA[<p>German, I&#8217;m not sure I understand what you&#8217;re saying.  For Y chromosome coalescence to have happened outside of Africa, all Y chromosome lineages in Africa would have to be derived from outside Africa, not just a majority.  Is that your contention?  My understanding is that Africa was still the likely location of Y chromosome coalescence, but I confess to not having followed the Y chromosome literature very carefully.</p>
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		<title>By: German Dziebel</title>
		<link>http://blogs.discovermagazine.com/gnxp/2010/12/the-paradigm-is-dead-long-live-the-paradigm/#comment-29420</link>
		<dc:creator>German Dziebel</dc:creator>
		<pubDate>Sun, 26 Dec 2010 23:55:28 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/gnxp/?p=8613#comment-29420</guid>
		<description>@Warren Dew:

&quot;The Y chromosome data rooting to Africa did provide evidence that a majority of our genes were from Africa.&quot;

In fact it provided the opposite: evidence that the majority of African lineages (hg E) are derived from outside of Africa. We ended up with hg AB in Africa and CDEF outside of Africa at about 40-45K (all pre-YAP+).

&quot;Kenichi Aoki of the University of Tokyo published a lovely simulation showing that after a colonizing cascade the root of a gene tree was as likely to be any of the daughters, oldest to newest, as any other. The implication was clear: the root of the mitochondrial tree in Africa could well mean nothing. &quot;

Very good. Now let&#039;s look at the map of linguistic diversity. (And let&#039;s ignore Greenberg and Ruhlen.) Interestingly, Melanesia, the inhabitatnts of which &quot;admixed&quot; with Denisovans, is one of the two regions with the highest levels of linguistic diversity. The other region is the New World.</description>
		<content:encoded><![CDATA[<p>@Warren Dew:</p>
<p>&#8220;The Y chromosome data rooting to Africa did provide evidence that a majority of our genes were from Africa.&#8221;</p>
<p>In fact it provided the opposite: evidence that the majority of African lineages (hg E) are derived from outside of Africa. We ended up with hg AB in Africa and CDEF outside of Africa at about 40-45K (all pre-YAP+).</p>
<p>&#8220;Kenichi Aoki of the University of Tokyo published a lovely simulation showing that after a colonizing cascade the root of a gene tree was as likely to be any of the daughters, oldest to newest, as any other. The implication was clear: the root of the mitochondrial tree in Africa could well mean nothing. &#8221;</p>
<p>Very good. Now let&#8217;s look at the map of linguistic diversity. (And let&#8217;s ignore Greenberg and Ruhlen.) Interestingly, Melanesia, the inhabitatnts of which &#8220;admixed&#8221; with Denisovans, is one of the two regions with the highest levels of linguistic diversity. The other region is the New World.</p>
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		<title>By: jld</title>
		<link>http://blogs.discovermagazine.com/gnxp/2010/12/the-paradigm-is-dead-long-live-the-paradigm/#comment-29419</link>
		<dc:creator>jld</dc:creator>
		<pubDate>Sun, 26 Dec 2010 17:00:35 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/gnxp/?p=8613#comment-29419</guid>
		<description>@Mike Gordon
&lt;i&gt;severe  mistreatment of groups designated as the &quot;other&quot;&lt;/i&gt;

Is a common feature of &lt;i&gt;any&lt;/i&gt; inter group competition, why should it be that it be seen as &quot;much worse&quot; when the groups are distinguished by ethnic criteria?</description>
		<content:encoded><![CDATA[<p>@Mike Gordon<br />
<i>severe  mistreatment of groups designated as the &#8220;other&#8221;</i></p>
<p>Is a common feature of <i>any</i> inter group competition, why should it be that it be seen as &#8220;much worse&#8221; when the groups are distinguished by ethnic criteria?</p>
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		<title>By: Dzagre</title>
		<link>http://blogs.discovermagazine.com/gnxp/2010/12/the-paradigm-is-dead-long-live-the-paradigm/#comment-29418</link>
		<dc:creator>Dzagre</dc:creator>
		<pubDate>Sun, 26 Dec 2010 04:07:45 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/gnxp/?p=8613#comment-29418</guid>
		<description>Stringer &amp; Andrews concluded their pivotal 1988 Science paper with the sentence:   &quot;As has been proved to be the case in the study of hominid origins, paleoanthropologists who ignore the increasing wealth of genetic data on human populations relationships do so at their own peril.&quot; Now one wonders if the same rules for them apply to DNA drawn from fossil people rather than placentas, none of which even came from Africa. In the same paper to account for morphological traits MRE theorists proposed to link fossil and recent Australasians, Stringer &amp; Andrews referred to native Australians as &quot;evolutionary reversals&quot; and in a NYT editorial Robin McKie and Chris Stringer called MRE and &quot;devisive theory,&quot; equating it with racism.  So, there was some justification for having fears of being labeled an opponent to the Eve theory. Racism was often leveled at MRE followers.
The revolution in paleogenetics is being matched in Neandertal archaeology, where most of the old ideas about Neandertal cultural incompetence are being overturned.  Now, new data even point to language origins extending well before the Neandertals.  And there is a lot more coming in 2011.</description>
		<content:encoded><![CDATA[<p>Stringer &amp; Andrews concluded their pivotal 1988 Science paper with the sentence:   &#8220;As has been proved to be the case in the study of hominid origins, paleoanthropologists who ignore the increasing wealth of genetic data on human populations relationships do so at their own peril.&#8221; Now one wonders if the same rules for them apply to DNA drawn from fossil people rather than placentas, none of which even came from Africa. In the same paper to account for morphological traits MRE theorists proposed to link fossil and recent Australasians, Stringer &amp; Andrews referred to native Australians as &#8220;evolutionary reversals&#8221; and in a NYT editorial Robin McKie and Chris Stringer called MRE and &#8220;devisive theory,&#8221; equating it with racism.  So, there was some justification for having fears of being labeled an opponent to the Eve theory. Racism was often leveled at MRE followers.<br />
The revolution in paleogenetics is being matched in Neandertal archaeology, where most of the old ideas about Neandertal cultural incompetence are being overturned.  Now, new data even point to language origins extending well before the Neandertals.  And there is a lot more coming in 2011.</p>
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		<title>By: Mike Gordon</title>
		<link>http://blogs.discovermagazine.com/gnxp/2010/12/the-paradigm-is-dead-long-live-the-paradigm/#comment-29417</link>
		<dc:creator>Mike Gordon</dc:creator>
		<pubDate>Sun, 26 Dec 2010 02:46:51 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/gnxp/?p=8613#comment-29417</guid>
		<description>We are all the same species in that we can and do interbreed and have fertile progeny.
Findings of genes in modern humans similar to genes in Neanderthals or Denisovans
tells us nothing about how we ought to treat each other societally, but they may be useful
medically, same as all other genome data.

Different gene frequencies do not justify disparate treatment but can serve as
an excuse for it. That&#039;s why racism is bad, irrespective of the science, to the extent that dominant groups use it to justify subjugation, and severe mistreatment of  groups designated as the &quot;other&quot;. Unfortunately, some people seem to have a need for a group they can look down on. Such groups are social constructs, and sometimes (e.g. Eta in Japan)  are physically indistinguishable from the dominant group.</description>
		<content:encoded><![CDATA[<p>We are all the same species in that we can and do interbreed and have fertile progeny.<br />
Findings of genes in modern humans similar to genes in Neanderthals or Denisovans<br />
tells us nothing about how we ought to treat each other societally, but they may be useful<br />
medically, same as all other genome data.</p>
<p>Different gene frequencies do not justify disparate treatment but can serve as<br />
an excuse for it. That&#8217;s why racism is bad, irrespective of the science, to the extent that dominant groups use it to justify subjugation, and severe mistreatment of  groups designated as the &#8220;other&#8221;. Unfortunately, some people seem to have a need for a group they can look down on. Such groups are social constructs, and sometimes (e.g. Eta in Japan)  are physically indistinguishable from the dominant group.</p>
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		<title>By: Miley Cyrax</title>
		<link>http://blogs.discovermagazine.com/gnxp/2010/12/the-paradigm-is-dead-long-live-the-paradigm/#comment-29416</link>
		<dc:creator>Miley Cyrax</dc:creator>
		<pubDate>Sun, 26 Dec 2010 00:51:55 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/gnxp/?p=8613#comment-29416</guid>
		<description>@ miko

&quot;I can never tell if people like you are merely stupid or willfully pretending that egalitarianism means something it doesn’t for ideological reasons.&quot;

Sometimes I can&#039;t tell if people like you are merely stupid, or willfully pretending that terms can&#039;t be borrowed from other contexts or have different meanings in different contexts. Or are didisdainful of Google:

First result for &quot;biological egalitariansim&quot; actually happens to be our own gnxp: http://www.gnxp.com/blog/2009/10/biological-egalitarianism.php

Ironically, we  don&#039;t have egalitarianism under the law (e.g. affirmative action, which is in violation of the equal protection clause but is exceptioned by the courts due to a &quot;compelling state interest&quot;), in part due to an unsubstantiated belief in biological egalitarianism.

&quot;enjoy imaging themselves victims of an ideological conspiracy, which is creepy and sad.&quot;
Do you mean sort of like how some blacks and latinos believe that &quot;the white man&quot; is constantly trying to keep them down? But I assume you mean some whites and Asians in respect to things like affirmative action, because they&#039;re socially acceptable targets .</description>
		<content:encoded><![CDATA[<p>@ miko</p>
<p>&#8220;I can never tell if people like you are merely stupid or willfully pretending that egalitarianism means something it doesn’t for ideological reasons.&#8221;</p>
<p>Sometimes I can&#8217;t tell if people like you are merely stupid, or willfully pretending that terms can&#8217;t be borrowed from other contexts or have different meanings in different contexts. Or are didisdainful of Google:</p>
<p>First result for &#8220;biological egalitariansim&#8221; actually happens to be our own gnxp: <a href="http://www.gnxp.com/blog/2009/10/biological-egalitarianism.php" rel="nofollow">http://www.gnxp.com/blog/2009/10/biological-egalitarianism.php</a></p>
<p>Ironically, we  don&#8217;t have egalitarianism under the law (e.g. affirmative action, which is in violation of the equal protection clause but is exceptioned by the courts due to a &#8220;compelling state interest&#8221;), in part due to an unsubstantiated belief in biological egalitarianism.</p>
<p>&#8220;enjoy imaging themselves victims of an ideological conspiracy, which is creepy and sad.&#8221;<br />
Do you mean sort of like how some blacks and latinos believe that &#8220;the white man&#8221; is constantly trying to keep them down? But I assume you mean some whites and Asians in respect to things like affirmative action, because they&#8217;re socially acceptable targets .</p>
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		<title>By: gcochran</title>
		<link>http://blogs.discovermagazine.com/gnxp/2010/12/the-paradigm-is-dead-long-live-the-paradigm/#comment-29415</link>
		<dc:creator>gcochran</dc:creator>
		<pubDate>Sat, 25 Dec 2010 17:37:44 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/gnxp/?p=8613#comment-29415</guid>
		<description>Obviously, you can&#039;t do anything with the mere fact that  average brain sizes vary by a couple of standard deviations  (from lowest to highest group ) - unless you know the causal gene variants.  In much the same way, there was no point in trying to domesticate the horse before someone sequenced its genome.  Unsound.</description>
		<content:encoded><![CDATA[<p>Obviously, you can&#8217;t do anything with the mere fact that  average brain sizes vary by a couple of standard deviations  (from lowest to highest group ) &#8211; unless you know the causal gene variants.  In much the same way, there was no point in trying to domesticate the horse before someone sequenced its genome.  Unsound.</p>
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		<title>By: miko</title>
		<link>http://blogs.discovermagazine.com/gnxp/2010/12/the-paradigm-is-dead-long-live-the-paradigm/#comment-29414</link>
		<dc:creator>miko</dc:creator>
		<pubDate>Sat, 25 Dec 2010 16:23:42 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/gnxp/?p=8613#comment-29414</guid>
		<description>Cyrax, egalitarianism does not depend on any particular version of human history, or anything in particular about humans at all. It is about social institutions and equality under the law, it has nothing to do with assuming that people are identical or equivalent. Obviously, we are not all the same height, and just as obviously can vary in any other quantitative trait. I can never tell if people like you are merely stupid or willfully pretending that egalitarianism means something it doesn&#039;t for ideological reasons.

For most of the behavioral and cognitive traits that certain kinds of people fetishize, there is nothing approaching adequate evidence for causal gene variants between groups, and there often seem to be highly emotional motivations for or against particular kinds of biological explanations for historical specifics. For this reason, I&#039;m agnostic on most of these and suspicious of the motives of people who whine that one interpretation or another is obvious but politically suppressed. My other annoyance is that very few of the people who seem obsessed with this seem to be involved or conversant with obtaining evidence, or even have a clear sense of what it would look like, and seem to actively enjoy imaging themselves victims of an ideological conspiracy, which is creepy and sad. Same goes with convoluted and baseless explanations for how some kinds of admixture must make you smart while other kinds make you stupid.

And before you post a bunch of social science citations with &quot;evidence&quot; for group genetic differences driving cognitive traits (or--my favorite--correlations between SNPs and Likert scale responses in college students), consider what a behavioral geneticist might consider compelling evidence. I&#039;ve said it before: just because human data is hard to get doesn&#039;t mean we should use lower evidentiary standards.</description>
		<content:encoded><![CDATA[<p>Cyrax, egalitarianism does not depend on any particular version of human history, or anything in particular about humans at all. It is about social institutions and equality under the law, it has nothing to do with assuming that people are identical or equivalent. Obviously, we are not all the same height, and just as obviously can vary in any other quantitative trait. I can never tell if people like you are merely stupid or willfully pretending that egalitarianism means something it doesn&#8217;t for ideological reasons.</p>
<p>For most of the behavioral and cognitive traits that certain kinds of people fetishize, there is nothing approaching adequate evidence for causal gene variants between groups, and there often seem to be highly emotional motivations for or against particular kinds of biological explanations for historical specifics. For this reason, I&#8217;m agnostic on most of these and suspicious of the motives of people who whine that one interpretation or another is obvious but politically suppressed. My other annoyance is that very few of the people who seem obsessed with this seem to be involved or conversant with obtaining evidence, or even have a clear sense of what it would look like, and seem to actively enjoy imaging themselves victims of an ideological conspiracy, which is creepy and sad. Same goes with convoluted and baseless explanations for how some kinds of admixture must make you smart while other kinds make you stupid.</p>
<p>And before you post a bunch of social science citations with &#8220;evidence&#8221; for group genetic differences driving cognitive traits (or&#8211;my favorite&#8211;correlations between SNPs and Likert scale responses in college students), consider what a behavioral geneticist might consider compelling evidence. I&#8217;ve said it before: just because human data is hard to get doesn&#8217;t mean we should use lower evidentiary standards.</p>
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		<title>By: Henry Harpending</title>
		<link>http://blogs.discovermagazine.com/gnxp/2010/12/the-paradigm-is-dead-long-live-the-paradigm/#comment-29413</link>
		<dc:creator>Henry Harpending</dc:creator>
		<pubDate>Sat, 25 Dec 2010 16:03:36 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/gnxp/?p=8613#comment-29413</guid>
		<description>Razib I think you are perhaps too abrupt with Warren Dew: I think his comments are right on the money.  For example when the original CSW paper came out Kenichi Aoki of the University of Tokyo published a lovely simulation showing that after a colonizing cascade the root of a gene tree was as likely to be any of the daughters, oldest to newest, as any other.  The implication was clear: the root of the mitochondrial tree in Africa could well mean nothing.  You are correct that this did not become the &#039;majority view&#039; but it was quite clear to those to whom it was clear.

Rogers, Eswaran, and I published a paper a few years ago claiming that genomic patterns denied the exclusive African origin model.  Again few paid attention although no one told us we were wrong.  People like Hammer and Wall and Long have also pointed out the same thing.

One interesting story here is the interaction between laboratory technologies and population genetics theory.  For the last decade or two the focus of our interest has been lab stuff, while before that much of the action was in population genetics, like coalescence theory.  Hence by citing the &#039;majority of researchers&#039; you are obscuring some interesting history.

And, BTW, Merry Christmas to you and everyone here.

Henry</description>
		<content:encoded><![CDATA[<p>Razib I think you are perhaps too abrupt with Warren Dew: I think his comments are right on the money.  For example when the original CSW paper came out Kenichi Aoki of the University of Tokyo published a lovely simulation showing that after a colonizing cascade the root of a gene tree was as likely to be any of the daughters, oldest to newest, as any other.  The implication was clear: the root of the mitochondrial tree in Africa could well mean nothing.  You are correct that this did not become the &#8216;majority view&#8217; but it was quite clear to those to whom it was clear.</p>
<p>Rogers, Eswaran, and I published a paper a few years ago claiming that genomic patterns denied the exclusive African origin model.  Again few paid attention although no one told us we were wrong.  People like Hammer and Wall and Long have also pointed out the same thing.</p>
<p>One interesting story here is the interaction between laboratory technologies and population genetics theory.  For the last decade or two the focus of our interest has been lab stuff, while before that much of the action was in population genetics, like coalescence theory.  Hence by citing the &#8216;majority of researchers&#8217; you are obscuring some interesting history.</p>
<p>And, BTW, Merry Christmas to you and everyone here.</p>
<p>Henry</p>
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