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	<title>Comments on: Harappa Ancestry Project @ N ~ 50</title>
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	<link>http://blogs.discovermagazine.com/gnxp/2011/03/harappa-ancestry-project-n-50/</link>
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		<title>By: Diogenes</title>
		<link>http://blogs.discovermagazine.com/gnxp/2011/03/harappa-ancestry-project-n-50/#comment-31256</link>
		<dc:creator>Diogenes</dc:creator>
		<pubDate>Sun, 13 Mar 2011 23:34:30 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/gnxp/?p=10281#comment-31256</guid>
		<description>For everyone else:
ADMIXTURE produces unbiased genuine results I believe. But you need to think what it&#039;s doing because it doesn&#039;t know better.
WAFR-Pygmies and San=1 less (very far away) pole. Also San and Pygmies likely significant WAFR admixture. Thus it pulls WAFR towards supposedly &quot;unadmixed&quot; Pygmies and San.
If you draw an &quot;admixed&quot; pop in a MDS without including its (more different) &quot;unadmixed&quot; parent, it becomes the &quot;unadmixed&quot; pole and you effectively change the MDS and corresponding distances.</description>
		<content:encoded><![CDATA[<p>For everyone else:<br />
ADMIXTURE produces unbiased genuine results I believe. But you need to think what it&#8217;s doing because it doesn&#8217;t know better.<br />
WAFR-Pygmies and San=1 less (very far away) pole. Also San and Pygmies likely significant WAFR admixture. Thus it pulls WAFR towards supposedly &#8220;unadmixed&#8221; Pygmies and San.<br />
If you draw an &#8220;admixed&#8221; pop in a MDS without including its (more different) &#8220;unadmixed&#8221; parent, it becomes the &#8220;unadmixed&#8221; pole and you effectively change the MDS and corresponding distances.</p>
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		<title>By: Diogenes</title>
		<link>http://blogs.discovermagazine.com/gnxp/2011/03/harappa-ancestry-project-n-50/#comment-31255</link>
		<dc:creator>Diogenes</dc:creator>
		<pubDate>Sun, 13 Mar 2011 23:16:01 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/gnxp/?p=10281#comment-31255</guid>
		<description>Contemporary West Africans (and above all contemporary East Africans) likely received unquantified significant &quot;back to Africa&quot; admixture (R1b, etc). Papuans were largely isolated, and there&#039;s that Denisovan story. I would tend to agree with Zack.
ADMIXTURE  is just a stupid computer program. Silicon is really not the best material available in nature for genuine intelligence (as opposed to solving straightforward logic puzzles).
ADMIXTURE needs to be managed instead of being relied on producing miraculous &quot;ex-machina&quot; results, and the new version tool has proven quite useful in allowing us to think while it does the boring work.

I think you were right South Asian populations are mostly Eastern Fertile Crescent+Kurgan (ANI)+some Yellow River+Native independent incipient neolithic (ASI)</description>
		<content:encoded><![CDATA[<p>Contemporary West Africans (and above all contemporary East Africans) likely received unquantified significant &#8220;back to Africa&#8221; admixture (R1b, etc). Papuans were largely isolated, and there&#8217;s that Denisovan story. I would tend to agree with Zack.<br />
ADMIXTURE  is just a stupid computer program. Silicon is really not the best material available in nature for genuine intelligence (as opposed to solving straightforward logic puzzles).<br />
ADMIXTURE needs to be managed instead of being relied on producing miraculous &#8220;ex-machina&#8221; results, and the new version tool has proven quite useful in allowing us to think while it does the boring work.</p>
<p>I think you were right South Asian populations are mostly Eastern Fertile Crescent+Kurgan (ANI)+some Yellow River+Native independent incipient neolithic (ASI)</p>
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		<title>By: arvind mishra</title>
		<link>http://blogs.discovermagazine.com/gnxp/2011/03/harappa-ancestry-project-n-50/#comment-31254</link>
		<dc:creator>arvind mishra</dc:creator>
		<pubDate>Sun, 13 Mar 2011 04:24:16 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/gnxp/?p=10281#comment-31254</guid>
		<description>I would appreciate an article over the topic from Zack written for lay people in easily understandable manner.</description>
		<content:encoded><![CDATA[<p>I would appreciate an article over the topic from Zack written for lay people in easily understandable manner.</p>
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		<title>By: RK</title>
		<link>http://blogs.discovermagazine.com/gnxp/2011/03/harappa-ancestry-project-n-50/#comment-31253</link>
		<dc:creator>RK</dc:creator>
		<pubDate>Sun, 13 Mar 2011 02:14:20 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/gnxp/?p=10281#comment-31253</guid>
		<description>I think Maharashtra actually has a higher population than Bihar, and it only has one participant so far.

The representation is even more skewed by caste, though. The Nadar and the Rowther are the only participants who clearly aren&#039;t from one of the &quot;forward classes.&quot;</description>
		<content:encoded><![CDATA[<p>I think Maharashtra actually has a higher population than Bihar, and it only has one participant so far.</p>
<p>The representation is even more skewed by caste, though. The Nadar and the Rowther are the only participants who clearly aren&#8217;t from one of the &#8220;forward classes.&#8221;</p>
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		<title>By: Zack</title>
		<link>http://blogs.discovermagazine.com/gnxp/2011/03/harappa-ancestry-project-n-50/#comment-31252</link>
		<dc:creator>Zack</dc:creator>
		<pubDate>Sat, 12 Mar 2011 23:07:46 +0000</pubDate>
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		<description>Papuans being the most distant is a consequence of excluding the San and Pygmy.</description>
		<content:encoded><![CDATA[<p>Papuans being the most distant is a consequence of excluding the San and Pygmy.</p>
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