Not the great stagnation

By Razib Khan | September 16, 2011 1:13 am

Dan MacArthur points me to this story on the sequencing of the West family. You can read the full paper in PLoS Genetics. When the price point for a full genome comes down to $1,000 or so I plan on getting the code for everyone in my immediate family, just like I got everyone genotyped (the latter was cheaper, but a full genome is a much richer data set for intra-familial comparison).

I generated the chart from the figures quoted in the article about the cost of full genome sequencing. I’m moderately familiar with this trend, but it still boggles my mind that we’ve shifted two orders of magnitude in four years! Nice to know that in some domains progress continues.

CATEGORIZED UNDER: Genetics, Genomics, Personal Genomics
  • Bob Dole

    It’s only gonna get cheaper:

  • Andrew S.

    The readership’s general reaction to the OpenPCR:

  • Lab Lemming

    It doesn’t seem like that long ago that sequencing the human genome was supposed to be our generation’s mission to the moon.

  • Emil

    i put the numbers into a graf program (Graph), and had it find an exponential function for it. After setting using x=Δ in years from 2007, I got the function f(x)=781934.41*0.28925076^x. Putting in x=6 gives rufly 460, so, in 2013, it will cost rufly that. That seems to be an okay number.

  • Ian

    @Lab Lemming – imagine what a trip to the moon would cost today if they hadn’t just shelved the whole project after a few successes.

  • Paul Ó Duḃṫaiġ

    The scaling above puts Moore’s Law to shame 😉

    Once it hits a reasonly price not only will I get my full genome sequenced I’ll also “Open Source” the results.

  • Clark

    Like the subtle reference to Tyler Cowen.

    I think the big question is when the availability of these cheap analysis will start to have broader practical implications for people. I have to imagine it’s going to happen eventually – I just wonder what regulatory hurdles will be in the way. I’m still annoyed that phage therapies can’t be used to treat drug resistant bacteria primarily due to FDA restrictions – I can’t see how personal genomics would work except via off label prescription but even then how do doctors get the data on what to do?


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About Razib Khan

I have degrees in biology and biochemistry, a passion for genetics, history, and philosophy, and shrimp is my favorite food. In relation to nationality I'm a American Northwesterner, in politics I'm a reactionary, and as for religion I have none (I'm an atheist). If you want to know more, see the links at


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