Comments on: Your child's genome before the 2nd trimester? http://blogs.discovermagazine.com/gnxp/2012/04/your-childs-genome-before-the-2nd-trimester/ Sat, 18 May 2013 12:05:00 +0000 hourly 1 http://wordpress.org/?v=3.4.2 By: Steve http://blogs.discovermagazine.com/gnxp/2012/04/your-childs-genome-before-the-2nd-trimester/#comment-42375 Steve Tue, 01 May 2012 18:02:58 +0000 http://blogs.discovermagazine.com/gnxp/?p=16556#comment-42375 Having been written in 1948, Heinlein's "Beyond This Horizon" is somewhat dated but does explore some of the moral issues involved in genetic engineering. Having been written in 1948, Heinlein’s “Beyond This Horizon” is somewhat dated but does explore some of the moral issues involved in genetic engineering.

]]> By: April Brown http://blogs.discovermagazine.com/gnxp/2012/04/your-childs-genome-before-the-2nd-trimester/#comment-42374 April Brown Tue, 01 May 2012 14:59:22 +0000 http://blogs.discovermagazine.com/gnxp/?p=16556#comment-42374 Really ticks me off that every cool new advance in prenatal assessment has to be accompanied by the question of whether the new technology can be used to detect gender (and thus feed into the sex selective terminations in some cultures). Really ticks me off that every cool new advance in prenatal assessment has to be accompanied by the question of whether the new technology can be used to detect gender (and thus feed into the sex selective terminations in some cultures).

]]> By: bob sykes http://blogs.discovermagazine.com/gnxp/2012/04/your-childs-genome-before-the-2nd-trimester/#comment-42373 bob sykes Tue, 01 May 2012 12:44:16 +0000 http://blogs.discovermagazine.com/gnxp/?p=16556#comment-42373 So, Lo opposes a woman's right to choose? So, Lo opposes a woman’s right to choose?

]]> By: Dm http://blogs.discovermagazine.com/gnxp/2012/04/your-childs-genome-before-the-2nd-trimester/#comment-42372 Dm Tue, 01 May 2012 04:19:58 +0000 http://blogs.discovermagazine.com/gnxp/?p=16556#comment-42372 Probably the application is for severe health conditions. Probably including de novo mutations hence the parents' exomes would have to be sequenced as well. For gattaca-style designer babies, only pre-implantation would have a veneer of acceptability; but typical pre-imp genetic tests have a whopping false positive and false negative rates, and unless it can be improved, it just won't make a good screen for arbitrary severe health conditions. Probably the application is for severe health conditions. Probably including de novo mutations hence the parents’ exomes would have to be sequenced as well.

For gattaca-style designer babies, only pre-implantation would have a veneer of acceptability; but typical pre-imp genetic tests have a whopping false positive and false negative rates, and unless it can be improved, it just won’t make a good screen for arbitrary severe health conditions.

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