Comments on: Genome sequencing of the unborn http://blogs.discovermagazine.com/gnxp/2012/06/genome-sequencing-of-the-unborn/ Wed, 19 Jun 2013 14:55:00 +0000 hourly 1 http://wordpress.org/?v=3.4.2 By: AG http://blogs.discovermagazine.com/gnxp/2012/06/genome-sequencing-of-the-unborn/#comment-43054 AG Wed, 13 Jun 2012 20:08:01 +0000 http://blogs.discovermagazine.com/gnxp/?p=16895#comment-43054 This might be marginal relavant. But for you information. Original research http://www.plosgenetics.org/article/info%3Adoi%2F10.1371%2Fjournal.pgen.0040037 Additional findings and correlation http://www.fightaging.org/archives/2012/06/telomeres-and-late-fatherhood.php Looks like Rushton scores another point. [re: rushton, make sure you have <a href="http://entitledtoanopinion.wordpress.com/2012/05/06/rushton-is-the-spengler-of-race-realism/" rel="nofollow">this sort of behavior</a> in your prior distribution (not the first time he's been caught in this sort of shit). -razib] This might be marginal relavant. But for you information.
Original research

http://www.plosgenetics.org/article/info%3Adoi%2F10.1371%2Fjournal.pgen.0040037
Additional findings and correlation
http://www.fightaging.org/archives/2012/06/telomeres-and-late-fatherhood.php

Looks like Rushton scores another point.

[re: rushton, make sure you have this sort of behavior in your prior distribution (not the first time he's been caught in this sort of shit). -razib]

]]> By: dave http://blogs.discovermagazine.com/gnxp/2012/06/genome-sequencing-of-the-unborn/#comment-43053 dave Thu, 07 Jun 2012 15:44:39 +0000 http://blogs.discovermagazine.com/gnxp/?p=16895#comment-43053 I hate to think of the scary, the mad scientist in the lab creating the "perfect human", just watched a good doc on savants, these geniuses it seems are predisposed to under developed, or over developed genes, focused attention like this could be very scary, just what the heck are we really looking for? When it's been found that sometimes we need these variants being that they're all interconnected and serve other purposes......... I hate to think of the scary, the mad scientist in the lab creating the “perfect human”, just watched a good doc on savants, these geniuses it seems are predisposed to under developed, or over developed genes, focused attention like this could be very scary, just what the heck are we really looking for? When it’s been found that sometimes we need these variants being that they’re all interconnected and serve other purposes………

]]> By: Razib Khan http://blogs.discovermagazine.com/gnxp/2012/06/genome-sequencing-of-the-unborn/#comment-43052 Razib Khan Thu, 07 Jun 2012 03:06:21 +0000 http://blogs.discovermagazine.com/gnxp/?p=16895#comment-43052 <i> more striking things was that they said he has a lower than average risk of alcoholism.</i> useless without a specific value/odds. though i think the long term of utility of this sort of thing isn't going to be in the small odds shifts you see in genotyping analyses. more striking things was that they said he has a lower than average risk of alcoholism.

useless without a specific value/odds. though i think the long term of utility of this sort of thing isn’t going to be in the small odds shifts you see in genotyping analyses.

]]> By: ackbark http://blogs.discovermagazine.com/gnxp/2012/06/genome-sequencing-of-the-unborn/#comment-43051 ackbark Thu, 07 Jun 2012 02:29:41 +0000 http://blogs.discovermagazine.com/gnxp/?p=16895#comment-43051 I just had my adoptive father's dna done at 23andMe and one of the more striking things was that they said he has a lower than average risk of alcoholism. Well, he's been drunk since 1935. I'm not making that up. But he is the kind of person, until he became elderly, would rarely actually look like he was drunk. I'm just mentioning that because it seems to me, at our present state of knowledge, tests like that could easily go way wrong. I just had my adoptive father’s dna done at 23andMe and one of the more striking things was that they said he has a lower than average risk of alcoholism.

Well, he’s been drunk since 1935. I’m not making that up. But he is the kind of person, until he became elderly, would rarely actually look like he was drunk.

I’m just mentioning that because it seems to me, at our present state of knowledge, tests like that could easily go way wrong.

]]> By: duende http://blogs.discovermagazine.com/gnxp/2012/06/genome-sequencing-of-the-unborn/#comment-43050 duende Thu, 07 Jun 2012 00:10:18 +0000 http://blogs.discovermagazine.com/gnxp/?p=16895#comment-43050 Although prenatal care of some sort can be normalized (almost all American babies are born in hospitals) the sort of "pregnancy projects" that affluent or well-educated go through to give their babies the best starts in life is something that will be almost impossible to impart to pregnant women who eat fast food every day, smoke etc. In the future babies born to poor or underclass women will be disadvantaged from the day they are conceived. And the future is now, Although prenatal care of some sort can be normalized (almost all American babies are born in hospitals) the sort of “pregnancy projects” that affluent or well-educated go through to give their babies the best starts in life is something that will be almost impossible to impart to pregnant women who eat fast food every day, smoke etc. In the future babies born to poor or underclass women will be disadvantaged from the day they are conceived. And the future is now,

]]> By: Dm http://blogs.discovermagazine.com/gnxp/2012/06/genome-sequencing-of-the-unborn/#comment-43049 Dm Wed, 06 Jun 2012 22:08:36 +0000 http://blogs.discovermagazine.com/gnxp/?p=16895#comment-43049 In fact one could argue that even for the known de novo mutations or rare heritable Mendelian disorders, the interpretation might leave room for doubt about direct causality and/or penetrance. They just aren't studied well enough, both on statistical and biochemical level. As to the uncharacterized variation, it's bad enough for adult's genome riddles, but it becomes a whole new level of uncertainty when parents have to ponder their possible dangers and/or advantages. I could see a world where every intelligent human being is prodded to take up a career in either genetic counseling, or genetic misinterpretation litigation. In fact one could argue that even for the known de novo mutations or rare heritable Mendelian disorders, the interpretation might leave room for doubt about direct causality and/or penetrance. They just aren’t studied well enough, both on statistical and biochemical level. As to the uncharacterized variation, it’s bad enough for adult’s genome riddles, but it becomes a whole new level of uncertainty when parents have to ponder their possible dangers and/or advantages.

I could see a world where every intelligent human being is prodded to take up a career in either genetic counseling, or genetic misinterpretation litigation.

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