Buyer beware in ancestry testing!

By Razib Khan | December 18, 2012 12:20 am

Over at Genomes Unzipped Vincent Plagnol has put up a post, Exaggerations and errors in the promotion of genetic ancestry testing, which to my mind is an understated and soft-touch old-fashioned “fisking” of the pronouncements of a spokesperson for an outfit termed Britain’s DNA. The whole post is worth reading, but this is a very grave aspect of the response of the company:

…The main reason is that listening to this radio interview prompted my UCL colleagues David Balding and Mark Thomas to ask questions to the Britain’s DNA scientific team; the questions have not been satisfactorily answered. Instead, a threat of legal action was issued by solicitors for Mr Moffat. Any type of legal threat is an ominous sign for an academic debate. This motivated me to point out some of the incorrect, or at the very least exaggerated, statements made in this interview. Importantly, while I received comments from several people for this post, the opinion presented here is entirely mine and does not involve any of my colleagues at Genomes Unzipped.

From what I can gather this firm is charging two to three times more than 23andMe for state-of-the-art scientific genealogy, circa 2002. So if you can’t be bothered to read the piece, it looks like Britain’s DNA is threatening litigation for researchers having the temerity to point out that the firm is providing substandard services at above-market costs. Plagnol’s critique lays out point-by-point refutation of assertions, but the interpretation services on offer seem to resemble nothing more than genetically rooted epic fantasy. A triumph of marketing over science.


In other scientific genealogy news, a friend recent sent me results for his family from Ancestry.com’s AncestryDNA service. Looking at the pie-charts, I can say one thing: they were whack! But the question then is are they truly just whack, or does their peculiarity indicate real genetic insight? I have no way to judge, because they still aren’t providing raw data downloads, though they promise to soon. I actually talked to a scientist from Ancestry.com for a little while at ASHG 2012, and he claimed that they were tweaking the algorithms as as we were speaking. Nevertheless, bizarre results still seem to abound. It would be nie to figure out the method to this madness.

Finally, the genomic angle to the Dan MacArthur → Dan MacCurry saga is approaching closure. My friend Zack Ajmal promises to put up his analysis before he goes on vacation. I asked Zack to look into the matter because he has a very large database of South Asians, and I want to see if he could find the best match to Dan’s chromosome 10. If it does turn out that it is highly probable that Dan’s South Asian ancestry is Bengali, then I’ll have to make sure he’s introduced to the aloo bhorta which his ancestors no doubt relished (and which is unpalatable to people of other South Asian ethnic groups because of the mustard oil).

CATEGORIZED UNDER: Personal Genomics
MORE ABOUT: Personal genomics

Comments are closed.

NEW ON DISCOVER
OPEN
CITIZEN SCIENCE
ADVERTISEMENT

Discover's Newsletter

Sign up to get the latest science news delivered weekly right to your inbox!

Gene Expression

This blog is about evolution, genetics, genomics and their interstices. Please beware that comments are aggressively moderated. Uncivil or churlish comments will likely get you banned immediately, so make any contribution count!

About Razib Khan

I have degrees in biology and biochemistry, a passion for genetics, history, and philosophy, and shrimp is my favorite food. In relation to nationality I'm a American Northwesterner, in politics I'm a reactionary, and as for religion I have none (I'm an atheist). If you want to know more, see the links at http://www.razib.com

ADVERTISEMENT

See More

ADVERTISEMENT

RSS Razib’s Pinboard

Edifying books

Collapse bottom bar
+

Login to your Account

X
E-mail address:
Password:
Remember me
Forgot your password?
No problem. Click here to have it e-mailed to you.

Not Registered Yet?

Register now for FREE. Registration only takes a few minutes to complete. Register now »