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Gene Expression

Archive for the ‘Futurism’ Category

Singularity Summit 2011

That time of the year for a certain type of nerd, the Singularity Summit. Here’s a a preview:

This Singularity Summit line-up this year features a mix of 25 speakers from numerous fields, with a central focus on robotics and artificial intelligence, in particular the victory of the IBM computer Watson in Jeopardy! this February. Inventor and award-winning author Ray Kurzweil will give the opening keynote on “From Eliza to Watson to Passing the Turing Test”. Registration for the Summit, which runs on October 15-16 at the 92Y in New York, is open to the public now.

The theme of the Summit this year is the Watson victory and future Watson applications, such as in medicine. Dan Cerutti, IBM’s VP of Commercialization for Watson, will give a talk on medical applications for Watson, and the closing keynote will be by Ken Jennings, who won 74 consecutiveJeopardy! matches only to lose to Watson in February. Watson won $1,000,000 in the contest and Jennings won $300,000, coming in second place. Jennings’ talk will be “The Human Brain in Jeopardy: Computers That “Think”.

I won’t be able to make it because I’m very busy right now, but that’s too bad. Ken Jennings is a great headliner, but do look at all the speakers. Tyler Cowen and Sonia Arrison will be there. I had lunch with some of the practitioners of Masonomics a few years back, but Tyler and Bryan Caplan were both out of town. No doubt the day will come. Just not this day. I haven’t had time to review 100 Plus (alas, the neglect of the Razib Khan on Books website), but it’s an excellent take on the possible implications of greater longevity (no, I don’t think longevity research is crazy as such, though I’m probably not as optimistic as many in the community).

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September 22nd, 2011 Tags: Singularity Summit, Transhumanism
by Razib Khan in Futurism | 10 Comments » | RSS feed | Trackback >

Eugenics as a luxury of the affluent

In the comments below Jason says in regards to the connection between eugenics and genocide and the “slippery slope”:

In your current comfortable first world circumstances, you are right the slope is perhaps not that slippery. I hope you are never tested in a less comfortable setting as then I think you might find it can be pretty slippery after all.

A reference to the interlocutor’s status as a citizen of the comfortable First World (which itself is a somewhat archaic term by now I think) seems de rigueur in many arguments. And I think many people will find it plausible that someone in an affluent consumer society would be blind to the “dark side” of eugenics, and how it could lead to genocide. But I think this plausibility is entirely superficial, and collapses upon closer inspection. Rather, it is I believe in “First World” and advanced nations where the likelihood of the ubiquity of eugenics and possible genocide predicated on systematic eugenics is going to be the most probable outcome.

(more…)

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August 24th, 2011 Tags: Eugenics, Health
by Razib Khan in Futurism, Health | 7 Comments » | RSS feed | Trackback >

Genetics existed before -omics

In the post below, Moderate marginal value to genomics, I left some things implicit. It turns out that this was an ill-considered decision. In reality my comments were simply more cryptic and opaque than implicit. This is pretty obvious because even those readers who are biologists didn’t seem to catch what I had assumed would be obvious in the thrust of my argument.

The point in the broadest sense is that DNA and genomics are not magical. Genetics existed before either of them. Understanding the physical basis of genetics has certainly been incredibly fruitful, and genomics has altered the playing field in many ways. But there was a broad understanding of genetics before DNA and genomics, both in a Mendelian sense and in the area of biometrics and quantitative genetics. In the earlier post I indicated that the tools for predictions of adult traits due to the effect of genes have been around for a long time: our family history. By this, I mean that a lot of traits of interest are substantially heritable. A great deal of the variation within the population can be explained by variation of genes in the population, as inferred by patterns of correlation between individuals in their traits as a function of genetic relatedness. This is genetics as a branch of applied statistics. It has great “quick & dirty” power, especially in agricultural science.

Let’s look at something simple, height. It’s a continuous trait which is rather concrete. No one argues that “height” is a social construct. In Western societies height is ~80-90% heritable. That means that most of the variation within the population of the trait can be explained by variation in one’s family background. Tall people have tall children, short people have short children, and so forth. Here’s a “toy” scatterplot which shows the relation between mid-parent heights and adult offspring heights (I made up the numbers):

(more…)

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June 9th, 2011 Tags: Behavior Genetics, Gattaca, Genetics, Genetics of Height, Genomics
by Razib Khan in Behavior Genetics, Futurism, Genetics, Genomics | 14 Comments » | RSS feed | Trackback >

Nuclear power as the “shark attacks” of energy



Image Credit: Stefan Kuhn

I was at a coffee shop recently and a SWPL couple (woman had dreads to boot!) a number of tables away were reading a newspaper, and the husband expressed worry about the Fukushima disaster. The wife responded that “now other people will understand how dangerous nuclear power is,” with a sage nod. They then launched into twenty minutes of loud righteous gibberish about chemicals (I had a hard time making sense of it, despite the fact that I learned a lot about chemicals in the past due to my biochemistry background). Because they’d irritated me I was curious and I tailed them as they left. Naturally they had driven to get coffee in a S.U.V. of some sort (albeit, a modestly sized one which looked like it was more outfitted for the outdoors’ activities common in the Pacific Northwest; they’d probably done their cost vs. benefit about those chemicals!).

In terms of radiation fears, I suspect that if more people just automatically knew the inverse-square law in relation to the drop off of its effects we’d be in a whole lot less public relations trouble. More obviously there is clearly a salience problem with nuclear disasters; people always notice them. For fossil fuels the negative environmental consequences usually don’t get so in your face as ‘fracking’. Or, they’re only really evident in godforsaken places like the Niger Delta. Of course people in Louisiana are well aware of the ‘Cancer Corridor’, but they seem to take it as the cost of doing business by and large. I have a hard time imagining such an equanimous attitude toward nuclear power. So I thought I’d pass on the 1000th article reiterating the obvious, Fossil fuels are far deadlier than nuclear power:

(more…)

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March 24th, 2011 Tags: Energy, Environmentalism, Nuclear Power
by Razib Khan in Environment, Futurism | 28 Comments » | RSS feed | Trackback >

Humanity+ conference in Pasadena

humaplusI was going to try and make it to the Humanity+ conference this year, but life intruded and the scheduling didn’t work out. Here’s the program. If you live in the LA area and this is your cup of tea, registration still looks open. Also check out H+ magazine. I noticed that my friend Michael Vassar seems more optimistic about the teens of the 21st century than he was a few years ago, Top 10 Reasons to expect the next 10 years to be more exciting than the last. I’m most excited by #2 b the way, if it’s viable.

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December 2nd, 2010 Tags: Conferences, Futurism, H+, Humanity+ conference
by Razib Khan in Futurism | 5 Comments » | RSS feed | Trackback >





    • About Gene Expression

      Razib Khan’s degrees are in biochemistry and biology. He has blogged about genetics since 2002, previously worked in software development, is an Unz Foundation Junior Fellow and lives in the western US. He loves habaneros.

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