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	<title>Comments on: An Open Mouse</title>
	<atom:link href="http://blogs.discovermagazine.com/loom/2007/05/24/an-open-mouse/feed/" rel="self" type="application/rss+xml" />
	<link>http://blogs.discovermagazine.com/loom/2007/05/24/an-open-mouse/</link>
	<description>A blog about life, past and future. Written by DISCOVER contributing editor and columnist Carl Zimmer.</description>
	<lastBuildDate>Mon, 13 Feb 2012 19:00:24 +0000</lastBuildDate>
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		<title>By: Your Yeasty Network &#124; The Loom &#124; Discover Magazine</title>
		<link>http://blogs.discovermagazine.com/loom/2007/05/24/an-open-mouse/comment-page-1/#comment-8464</link>
		<dc:creator>Your Yeasty Network &#124; The Loom &#124; Discover Magazine</dc:creator>
		<pubDate>Mon, 28 Jul 2008 04:31:56 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/loom/2007/05/24/an-open-mouse/#comment-8464</guid>
		<description>[...] weekend I came across a wonderful illustration in a new paper that I&#8217;ve goosed up (thanks, open access!). The subject of the paper is the way our proteins work together. Many proteins work by first [...]</description>
		<content:encoded><![CDATA[<p>[...] weekend I came across a wonderful illustration in a new paper that I&#8217;ve goosed up (thanks, open access!). The subject of the paper is the way our proteins work together. Many proteins work by first [...]</p>
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		<title>By: Pumpkinhead</title>
		<link>http://blogs.discovermagazine.com/loom/2007/05/24/an-open-mouse/comment-page-1/#comment-4969</link>
		<dc:creator>Pumpkinhead</dc:creator>
		<pubDate>Tue, 12 Jun 2007 11:46:45 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/loom/2007/05/24/an-open-mouse/#comment-4969</guid>
		<description>You sometimes hear people talking about the &quot;gay gene,&quot; the &quot;depression gene,&quot; and so on. But this view is almost entirely divorced from reality


It seems this prominent evolutionist let a little truth seep through his dyke of ideology. I wonder if he will stick by this quote when the hordes of pink faeries descend like locusts on upon his next speaking engagement. Even if he doesn&#039;t, this quote will surely be in the next issue of our church newsletter!</description>
		<content:encoded><![CDATA[<p>You sometimes hear people talking about the &#8220;gay gene,&#8221; the &#8220;depression gene,&#8221; and so on. But this view is almost entirely divorced from reality</p>
<p>It seems this prominent evolutionist let a little truth seep through his dyke of ideology. I wonder if he will stick by this quote when the hordes of pink faeries descend like locusts on upon his next speaking engagement. Even if he doesn&#8217;t, this quote will surely be in the next issue of our church newsletter!</p>
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		<title>By: M.C.Arunan</title>
		<link>http://blogs.discovermagazine.com/loom/2007/05/24/an-open-mouse/comment-page-1/#comment-4968</link>
		<dc:creator>M.C.Arunan</dc:creator>
		<pubDate>Sat, 09 Jun 2007 06:17:26 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/loom/2007/05/24/an-open-mouse/#comment-4968</guid>
		<description>Open access jounals like PLoS Biology is the only hope for university and college teachers like me in India to be still optimistic despite the the tendency of the state to withdraw from funding of public education. This, when as large as 94% of the population of the age group between 18-24 do not find a place in  higher educational institution in the country.</description>
		<content:encoded><![CDATA[<p>Open access jounals like PLoS Biology is the only hope for university and college teachers like me in India to be still optimistic despite the the tendency of the state to withdraw from funding of public education. This, when as large as 94% of the population of the age group between 18-24 do not find a place in  higher educational institution in the country.</p>
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		<title>By: Keith</title>
		<link>http://blogs.discovermagazine.com/loom/2007/05/24/an-open-mouse/comment-page-1/#comment-4967</link>
		<dc:creator>Keith</dc:creator>
		<pubDate>Mon, 28 May 2007 16:43:01 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/loom/2007/05/24/an-open-mouse/#comment-4967</guid>
		<description>I wonder if increasing the transparency of how money is used would be beneficial for an OA journal? If for instance PLOS were to openly list how much money they have and how it is being spent, then other people might be able to donate or volunteer to help for areas where funding is insufficent. Another idea would be to make it easier for people to donate or volunteer in other non-monetary ways. If a lot of money was being sucked out each month for server hardware or web-design issues, perhaps people or organizations who care about OA publishing would step to the plate and offer to donate needed hardware, or help out with some of the web-design.</description>
		<content:encoded><![CDATA[<p>I wonder if increasing the transparency of how money is used would be beneficial for an OA journal? If for instance PLOS were to openly list how much money they have and how it is being spent, then other people might be able to donate or volunteer to help for areas where funding is insufficent. Another idea would be to make it easier for people to donate or volunteer in other non-monetary ways. If a lot of money was being sucked out each month for server hardware or web-design issues, perhaps people or organizations who care about OA publishing would step to the plate and offer to donate needed hardware, or help out with some of the web-design.</p>
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		<title>By: Jonathan Eisen</title>
		<link>http://blogs.discovermagazine.com/loom/2007/05/24/an-open-mouse/comment-page-1/#comment-4966</link>
		<dc:creator>Jonathan Eisen</dc:creator>
		<pubDate>Fri, 25 May 2007 22:15:58 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/loom/2007/05/24/an-open-mouse/#comment-4966</guid>
		<description>I like that everyone seems to agree that Open Access is a good thing.  Now what we need to do is to figure out the best ways to implement it so that it works for all (e.g., for poorer fields such as ecology).  I think there are a few things we can all do to help make this happen

1. Lobby the government to make OA publishing a requirement in exchange for federal funding

2. Lobby the government to provide supplemental funds to cover the costs.  This is economically reasonable since the true costs of OA publishing are lower than non OA publishing (e.g., libraries do not have to buy subscriptions, there are no fees for reuse, etc).

3. Work with society publishers in all fields, especially the poorer ones, to switch to at least a partial OA model

4. Stop volunteering your time to work for non OA journals.  Volunteer for the OA ones.  Then the costs will go down.  A lot of the reason that non OA journals can be so cheap is that so many scientists review/edit for them for free.

5. Apply to funding agencies for grants to support OA journals.  Just as funding agencies support conferences, workshops and courses, they should support OA journals.

6. Make use of institutional and other repositories through which you can place preprints even those for non OA journals.  The more these are used the better.

7. Submit to journals that have a fee waiver such as the PLoS journals when needed.

8. Pay the OA fees if you can afford it.

9. Make better use of OA material for blogs, courses, textbooks, etc.  The more it gets used the more the funding agencies will support paying for it.

10+.  I am sure they are other things ...</description>
		<content:encoded><![CDATA[<p>I like that everyone seems to agree that Open Access is a good thing.  Now what we need to do is to figure out the best ways to implement it so that it works for all (e.g., for poorer fields such as ecology).  I think there are a few things we can all do to help make this happen</p>
<p>1. Lobby the government to make OA publishing a requirement in exchange for federal funding</p>
<p>2. Lobby the government to provide supplemental funds to cover the costs.  This is economically reasonable since the true costs of OA publishing are lower than non OA publishing (e.g., libraries do not have to buy subscriptions, there are no fees for reuse, etc).</p>
<p>3. Work with society publishers in all fields, especially the poorer ones, to switch to at least a partial OA model</p>
<p>4. Stop volunteering your time to work for non OA journals.  Volunteer for the OA ones.  Then the costs will go down.  A lot of the reason that non OA journals can be so cheap is that so many scientists review/edit for them for free.</p>
<p>5. Apply to funding agencies for grants to support OA journals.  Just as funding agencies support conferences, workshops and courses, they should support OA journals.</p>
<p>6. Make use of institutional and other repositories through which you can place preprints even those for non OA journals.  The more these are used the better.</p>
<p>7. Submit to journals that have a fee waiver such as the PLoS journals when needed.</p>
<p>8. Pay the OA fees if you can afford it.</p>
<p>9. Make better use of OA material for blogs, courses, textbooks, etc.  The more it gets used the more the funding agencies will support paying for it.</p>
<p>10+.  I am sure they are other things &#8230;</p>
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		<title>By: Jerry D. Harris</title>
		<link>http://blogs.discovermagazine.com/loom/2007/05/24/an-open-mouse/comment-page-1/#comment-4965</link>
		<dc:creator>Jerry D. Harris</dc:creator>
		<pubDate>Fri, 25 May 2007 20:04:47 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/loom/2007/05/24/an-open-mouse/#comment-4965</guid>
		<description>Don&#039;t get me wrong, I&#039;m &lt;b&gt;all&lt;/b&gt; for open access (with or without caps) and anything else that increases freedom of the spread of information, especially between scientists, but in its present incarnation, it is highly prejudicial and, for that reason, will ultimately fail -- well, at least, it will ultimately severely limit the spread of some kinds of information at the expense of others.

Having recently submitted a paper to (and gotten reject from) &lt;i&gt;PLoS Biology&lt;/i&gt;, I noted during the whole process that PLoS strongly requested* US$2500 up front in order to &lt;i&gt;make&lt;/i&gt; an accepted paper &quot;open access.&quot;  I&#039;m not really complaining about that -- in the absence of revenue generated by subscriptions (or advertising...ugh, I hate to think about ads in scientific journals...!), I fully understand that they have to get the money to stay afloat while providing free access from &lt;i&gt;some&lt;/i&gt;where. What I have a problem with is that not every science -- I might venture (sans data) to think that &lt;i&gt;most&lt;/i&gt; sciences -- is awash with lavish grant monies with which to cover such fees.  Certainly the sciences with substantial and relatively short-order scientific boons, like genetics, biotechnology, pharmacology, etc. -- sciences that can benefit the tax-paying public at large in (relatively) short order -- get lots of grant money, both public and private, and can much more easily cover open access fees.  Most sciences, however, do not fit this mold -- many sciences, such as many aspects of geoscience, most biological disciplines, much of astrophysics, etc., do not have such short-term returns -- they are more about establishing the fundamentals that can be used over a much longer term to better understand the universe in which we live; only in the longer term do the economic benefits of such knowledge typically appear. But because we live in a free-market, capitalistic society, the economy itself determines where the money goes, and it by and large goes to short-term return projects. Thus, a vast number of scientists either cannot get grants (at least not large ones) or get only partial funding that has to be applied to time, equipment, etc. rather than open access fees.

*&lt;i&gt;I say &quot;strongly request&quot; because PLoS does state that papers won&#039;t necessarily be rejected, or not made open access, if the authors don&#039;t have the funds to pay the fee, which is good...but I think it&#039;s fairly obvious what could happen to that system if it were abused too much!&lt;/i&gt;

The fault is not with open access, which is a terrific concept in principle and, I suspect, practice, and not even with any one entity in particular, be they science organization, publisher, or granting agency.  But it is a sad side effect of the trend toward open access that the poorest (in a financial sense) sciences will be the last to reap the benefits. Subscription-based access to journals, at least, had the benefit of leveling the playing field to a greater extent, though even there biases were apparent, and of course subscription rates were and are bizarrely exorbitant, which greatly limited access for many.  I don&#039;t pretend to have a solution; I just think that something more equitable across all sciences needs to be implemented.</description>
		<content:encoded><![CDATA[<p>Don&#8217;t get me wrong, I&#8217;m <b>all</b> for open access (with or without caps) and anything else that increases freedom of the spread of information, especially between scientists, but in its present incarnation, it is highly prejudicial and, for that reason, will ultimately fail &#8212; well, at least, it will ultimately severely limit the spread of some kinds of information at the expense of others.</p>
<p>Having recently submitted a paper to (and gotten reject from) <i>PLoS Biology</i>, I noted during the whole process that PLoS strongly requested* US$2500 up front in order to <i>make</i> an accepted paper &#8220;open access.&#8221;  I&#8217;m not really complaining about that &#8212; in the absence of revenue generated by subscriptions (or advertising&#8230;ugh, I hate to think about ads in scientific journals&#8230;!), I fully understand that they have to get the money to stay afloat while providing free access from <i>some</i>where. What I have a problem with is that not every science &#8212; I might venture (sans data) to think that <i>most</i> sciences &#8212; is awash with lavish grant monies with which to cover such fees.  Certainly the sciences with substantial and relatively short-order scientific boons, like genetics, biotechnology, pharmacology, etc. &#8212; sciences that can benefit the tax-paying public at large in (relatively) short order &#8212; get lots of grant money, both public and private, and can much more easily cover open access fees.  Most sciences, however, do not fit this mold &#8212; many sciences, such as many aspects of geoscience, most biological disciplines, much of astrophysics, etc., do not have such short-term returns &#8212; they are more about establishing the fundamentals that can be used over a much longer term to better understand the universe in which we live; only in the longer term do the economic benefits of such knowledge typically appear. But because we live in a free-market, capitalistic society, the economy itself determines where the money goes, and it by and large goes to short-term return projects. Thus, a vast number of scientists either cannot get grants (at least not large ones) or get only partial funding that has to be applied to time, equipment, etc. rather than open access fees.</p>
<p>*<i>I say &#8220;strongly request&#8221; because PLoS does state that papers won&#8217;t necessarily be rejected, or not made open access, if the authors don&#8217;t have the funds to pay the fee, which is good&#8230;but I think it&#8217;s fairly obvious what could happen to that system if it were abused too much!</i></p>
<p>The fault is not with open access, which is a terrific concept in principle and, I suspect, practice, and not even with any one entity in particular, be they science organization, publisher, or granting agency.  But it is a sad side effect of the trend toward open access that the poorest (in a financial sense) sciences will be the last to reap the benefits. Subscription-based access to journals, at least, had the benefit of leveling the playing field to a greater extent, though even there biases were apparent, and of course subscription rates were and are bizarrely exorbitant, which greatly limited access for many.  I don&#8217;t pretend to have a solution; I just think that something more equitable across all sciences needs to be implemented.</p>
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		<title>By: Mark Johnston</title>
		<link>http://blogs.discovermagazine.com/loom/2007/05/24/an-open-mouse/comment-page-1/#comment-4964</link>
		<dc:creator>Mark Johnston</dc:creator>
		<pubDate>Fri, 25 May 2007 19:36:06 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/loom/2007/05/24/an-open-mouse/#comment-4964</guid>
		<description>Yes, open access publishing is wonderful.  It&#039;s the way it should be done in the best of all possible worlds.  But somebody has to pay for it. As I understand it, HHMI subsidizes the cost of publication in PLoS journals.  I hope that&#039;s sustainable, because the amount of money provided by my grants (which pays the cost of publishing my papers) doesn&#039;t seem to be increasing.</description>
		<content:encoded><![CDATA[<p>Yes, open access publishing is wonderful.  It&#8217;s the way it should be done in the best of all possible worlds.  But somebody has to pay for it. As I understand it, HHMI subsidizes the cost of publication in PLoS journals.  I hope that&#8217;s sustainable, because the amount of money provided by my grants (which pays the cost of publishing my papers) doesn&#8217;t seem to be increasing.</p>
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		<title>By: Maxine</title>
		<link>http://blogs.discovermagazine.com/loom/2007/05/24/an-open-mouse/comment-page-1/#comment-4963</link>
		<dc:creator>Maxine</dc:creator>
		<pubDate>Fri, 25 May 2007 11:07:46 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/loom/2007/05/24/an-open-mouse/#comment-4963</guid>
		<description>Nature, and the Nature Publishing Group journals, allow up to three figures to be reproduced for free. Pedro Belatro, a bioinformaticist, has compared journal publisher policies here:
&lt;a href=&quot;http://blogs.nature.com/nautilus/2007/03/journals_picture_copyright_pol.html&quot; rel=&quot;nofollow&quot;&gt;http://blogs.nature.com/nautilus/2007/03/journals_picture_copyright_pol.html&lt;/a&gt;

Luca: PLOS has a charitable endowment. Also many publishers, NPG included, encourage authors to archive into PMC and their institutional archives, without restriction. At NPG, we explain this to authors when they have a paper accepted for publication.</description>
		<content:encoded><![CDATA[<p>Nature, and the Nature Publishing Group journals, allow up to three figures to be reproduced for free. Pedro Belatro, a bioinformaticist, has compared journal publisher policies here:<br />
<a href="http://blogs.nature.com/nautilus/2007/03/journals_picture_copyright_pol.html" rel="nofollow">http://blogs.nature.com/nautilus/2007/03/journals_picture_copyright_pol.html</a></p>
<p>Luca: PLOS has a charitable endowment. Also many publishers, NPG included, encourage authors to archive into PMC and their institutional archives, without restriction. At NPG, we explain this to authors when they have a paper accepted for publication.</p>
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		<title>By: luca</title>
		<link>http://blogs.discovermagazine.com/loom/2007/05/24/an-open-mouse/comment-page-1/#comment-4962</link>
		<dc:creator>luca</dc:creator>
		<pubDate>Fri, 25 May 2007 06:50:04 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/loom/2007/05/24/an-open-mouse/#comment-4962</guid>
		<description>I also advocate free access to information, especially if publicly funded. &lt;a / rel=&quot;nofollow&quot;&gt;My old university introduced such a policy, and they&#039;ve been making available every paper published by them on their servers, as far as I know.

As for PLOS and other such journals, I guess it&#039;ll take some time for dubious scientists to get confident with them. If good research is published there, the Impact factor will grow quickly and more and more people will feel like trying it.

But, how do these journals fund things such as servers, editing, and so on?

I did review a paper once, so I know this is free of charge for them - but the reviewers do actually spend quite some time on it. Doesn&#039;t PLOS need some permanent employee (secretary, or so) to take care of submissions, applications etc.</description>
		<content:encoded><![CDATA[<p>I also advocate free access to information, especially if publicly funded. <a / rel="nofollow">My old university introduced such a policy, and they&#8217;ve been making available every paper published by them on their servers, as far as I know.</p>
<p>As for PLOS and other such journals, I guess it&#8217;ll take some time for dubious scientists to get confident with them. If good research is published there, the Impact factor will grow quickly and more and more people will feel like trying it.</p>
<p>But, how do these journals fund things such as servers, editing, and so on?</p>
<p>I did review a paper once, so I know this is free of charge for them &#8211; but the reviewers do actually spend quite some time on it. Doesn&#8217;t PLOS need some permanent employee (secretary, or so) to take care of submissions, applications etc.</a></p>
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		<title>By: Jon H</title>
		<link>http://blogs.discovermagazine.com/loom/2007/05/24/an-open-mouse/comment-page-1/#comment-4961</link>
		<dc:creator>Jon H</dc:creator>
		<pubDate>Fri, 25 May 2007 05:53:23 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/loom/2007/05/24/an-open-mouse/#comment-4961</guid>
		<description>Oh dear, I hope some nutter doesn&#039;t read this and decide that those mice need freeing.</description>
		<content:encoded><![CDATA[<p>Oh dear, I hope some nutter doesn&#8217;t read this and decide that those mice need freeing.</p>
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		<title>By: Allison Hawxhurst</title>
		<link>http://blogs.discovermagazine.com/loom/2007/05/24/an-open-mouse/comment-page-1/#comment-4960</link>
		<dc:creator>Allison Hawxhurst</dc:creator>
		<pubDate>Fri, 25 May 2007 01:38:04 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/loom/2007/05/24/an-open-mouse/#comment-4960</guid>
		<description>Thanks for using the PLoS Genetics figure--and for your support of Open Access publishing!
Figured I&#039;d break the silence from &lt;a href=&quot;http://www.plos.org&quot; rel=&quot;nofollow&quot;&gt;PLoS&lt;/a&gt; to say that we always appreciate it when our content is reused. We&#039;ve even put up a link to your post on our websites (see &quot;No Muss/No Fuss&quot; with the green recycle icon on &lt;a href=&quot;http://genetics.plosjournals.org/perlserv/?request=index-html&amp;issn=1553-7404&quot; rel=&quot;nofollow&quot;&gt;PLoS Genetics&lt;/a&gt;).</description>
		<content:encoded><![CDATA[<p>Thanks for using the PLoS Genetics figure&#8211;and for your support of Open Access publishing!<br />
Figured I&#8217;d break the silence from <a href="http://www.plos.org" rel="nofollow">PLoS</a> to say that we always appreciate it when our content is reused. We&#8217;ve even put up a link to your post on our websites (see &#8220;No Muss/No Fuss&#8221; with the green recycle icon on <a href="http://genetics.plosjournals.org/perlserv/?request=index-html&amp;issn=1553-7404" rel="nofollow">PLoS Genetics</a>).</p>
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		<title>By: llewelly</title>
		<link>http://blogs.discovermagazine.com/loom/2007/05/24/an-open-mouse/comment-page-1/#comment-4959</link>
		<dc:creator>llewelly</dc:creator>
		<pubDate>Fri, 25 May 2007 01:34:28 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/loom/2007/05/24/an-open-mouse/#comment-4959</guid>
		<description>That diagram resembles a rat&#039;s nest.
What idiot designed that code?</description>
		<content:encoded><![CDATA[<p>That diagram resembles a rat&#8217;s nest.<br />
What idiot designed that code?</p>
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		<title>By: Owlmirror</title>
		<link>http://blogs.discovermagazine.com/loom/2007/05/24/an-open-mouse/comment-page-1/#comment-4958</link>
		<dc:creator>Owlmirror</dc:creator>
		<pubDate>Fri, 25 May 2007 01:18:38 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/loom/2007/05/24/an-open-mouse/#comment-4958</guid>
		<description>In addition to genetic factors in fat formation, there certainly seems to be nongenetic factors involved with obesity as well; specifically, gut bacteria population.

PDFs of the various papers here, as well as interesting related research into symbiosis:

&#8195; &lt;a href=&quot;http://gordonlab.wustl.edu/Publications.html&quot; rel=&quot;nofollow&quot;&gt;http://gordonlab.wustl.edu/Publications.html&lt;/a&gt;</description>
		<content:encoded><![CDATA[<p>In addition to genetic factors in fat formation, there certainly seems to be nongenetic factors involved with obesity as well; specifically, gut bacteria population.</p>
<p>PDFs of the various papers here, as well as interesting related research into symbiosis:</p>
<p>&emsp; <a href="http://gordonlab.wustl.edu/Publications.html" rel="nofollow">http://gordonlab.wustl.edu/Publications.html</a></p>
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		<title>By: John Garrett</title>
		<link>http://blogs.discovermagazine.com/loom/2007/05/24/an-open-mouse/comment-page-1/#comment-4957</link>
		<dc:creator>John Garrett</dc:creator>
		<pubDate>Thu, 24 May 2007 23:16:51 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/loom/2007/05/24/an-open-mouse/#comment-4957</guid>
		<description>Re fair use - what publishers forget to mention is that the many abstract journals (publications which provide only abstracts of scientific articles) do so without permission of the publisher; if publishers complain, they stop publishing abstracts of their journals, eliminating a major source of publicity.  A quick descent from their high horse.</description>
		<content:encoded><![CDATA[<p>Re fair use &#8211; what publishers forget to mention is that the many abstract journals (publications which provide only abstracts of scientific articles) do so without permission of the publisher; if publishers complain, they stop publishing abstracts of their journals, eliminating a major source of publicity.  A quick descent from their high horse.</p>
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		<title>By: Ben</title>
		<link>http://blogs.discovermagazine.com/loom/2007/05/24/an-open-mouse/comment-page-1/#comment-4956</link>
		<dc:creator>Ben</dc:creator>
		<pubDate>Thu, 24 May 2007 16:02:54 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/loom/2007/05/24/an-open-mouse/#comment-4956</guid>
		<description>For a humorous look at Fair Use, you might also check out the video &lt;a href=&quot;http://www.youtube.com/watch?v=CJn_jC4FNDo&quot; rel=&quot;nofollow&quot;&gt;A Fair(y) Tale&lt;/a&gt; by Eric Faden.

Explains the whole issue in ten minutes of &#039;fairly used&#039; comedy.</description>
		<content:encoded><![CDATA[<p>For a humorous look at Fair Use, you might also check out the video <a href="http://www.youtube.com/watch?v=CJn_jC4FNDo" rel="nofollow">A Fair(y) Tale</a> by Eric Faden.</p>
<p>Explains the whole issue in ten minutes of &#8216;fairly used&#8217; comedy.</p>
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		<title>By: D Fitch</title>
		<link>http://blogs.discovermagazine.com/loom/2007/05/24/an-open-mouse/comment-page-1/#comment-4955</link>
		<dc:creator>D Fitch</dc:creator>
		<pubDate>Thu, 24 May 2007 15:28:39 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/loom/2007/05/24/an-open-mouse/#comment-4955</guid>
		<description>Your link to the Discover article skips to page 3; here&#039;s one for the start of the article.

&lt;a href=&quot;http://discovermagazine.com/2007/may/mendel2019s-mouse/article_view?b_start:int=0&amp;-C=&quot; rel=&quot;nofollow&quot;&gt;http://discovermagazine.com/2007/may/mendel2019s-mouse/article_view?b_start:int=0&amp;-C=&lt;/a&gt;

Fascinating writing, as per usual. Thanks!</description>
		<content:encoded><![CDATA[<p>Your link to the Discover article skips to page 3; here&#8217;s one for the start of the article.</p>
<p><a href="http://discovermagazine.com/2007/may/mendel2019s-mouse/article_view?b_start:int=0&amp;-C=" rel="nofollow">http://discovermagazine.com/2007/may/mendel2019s-mouse/article_view?b_start:int=0&#038;-C=</a></p>
<p>Fascinating writing, as per usual. Thanks!</p>
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		<title>By: Carl Zimmer</title>
		<link>http://blogs.discovermagazine.com/loom/2007/05/24/an-open-mouse/comment-page-1/#comment-4954</link>
		<dc:creator>Carl Zimmer</dc:creator>
		<pubDate>Thu, 24 May 2007 13:03:34 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/loom/2007/05/24/an-open-mouse/#comment-4954</guid>
		<description>GueSt [#1]: The gene you point to certainly does seem to have a major influence. However, its influence arises from controlling other genes. I wouldn&#039;t be surprised if variations in those downstream genes have an effect on levels of aggression, etc. Also, this gene may be a relatively rare example. As I write in my article, even the color of a mouse&#039;s fur is controlled by several genes. And major diseases appear to be controlled by many more. Single-gene diseases are pretty  rare, for basic evolutionary reasons: they can be easily elminated from the population through natural selection.</description>
		<content:encoded><![CDATA[<p>GueSt [#1]: The gene you point to certainly does seem to have a major influence. However, its influence arises from controlling other genes. I wouldn&#8217;t be surprised if variations in those downstream genes have an effect on levels of aggression, etc. Also, this gene may be a relatively rare example. As I write in my article, even the color of a mouse&#8217;s fur is controlled by several genes. And major diseases appear to be controlled by many more. Single-gene diseases are pretty  rare, for basic evolutionary reasons: they can be easily elminated from the population through natural selection.</p>
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		<title>By: Ed Yong</title>
		<link>http://blogs.discovermagazine.com/loom/2007/05/24/an-open-mouse/comment-page-1/#comment-4953</link>
		<dc:creator>Ed Yong</dc:creator>
		<pubDate>Thu, 24 May 2007 09:34:07 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/loom/2007/05/24/an-open-mouse/#comment-4953</guid>
		<description>I *love* that diagram and the build-up to it :-) It just perfectly illustrates why the discovery of a single &#039;fat gene&#039; is completely unrealistic. I think the other common misconception about the &lt;a href=&quot;http://notexactlyrocketscience.wordpress.com/2007/04/14/opinion-discovery-of-%e2%80%98fat-gene%e2%80%99-highlights-stigma-against-obese-people/&quot; rel=&quot;nofollow&quot;&gt;genetic influences of obesity&lt;/a&gt;, for example, is that people believe that any discovered genes flip on a simple switch from &#039;Obesity off&#039; to &#039;Obesity on&#039;. In reality, any obesity-related genes (or in fact, any depression- or gay-related genes) will probably exert their effects through very subtle behavioural changes, and this really needs to come across better in science journalism.</description>
		<content:encoded><![CDATA[<p>I *love* that diagram and the build-up to it <img src='http://blogs.discovermagazine.com/loom/wp-includes/images/smilies/icon_smile.gif' alt=':-)' class='wp-smiley' />  It just perfectly illustrates why the discovery of a single &#8216;fat gene&#8217; is completely unrealistic. I think the other common misconception about the <a href="http://notexactlyrocketscience.wordpress.com/2007/04/14/opinion-discovery-of-%e2%80%98fat-gene%e2%80%99-highlights-stigma-against-obese-people/" rel="nofollow">genetic influences of obesity</a>, for example, is that people believe that any discovered genes flip on a simple switch from &#8216;Obesity off&#8217; to &#8216;Obesity on&#8217;. In reality, any obesity-related genes (or in fact, any depression- or gay-related genes) will probably exert their effects through very subtle behavioural changes, and this really needs to come across better in science journalism.</p>
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		<title>By: GueSt</title>
		<link>http://blogs.discovermagazine.com/loom/2007/05/24/an-open-mouse/comment-page-1/#comment-4952</link>
		<dc:creator>GueSt</dc:creator>
		<pubDate>Thu, 24 May 2007 09:12:16 +0000</pubDate>
		<guid isPermaLink="false">http://blogs.discovermagazine.com/loom/2007/05/24/an-open-mouse/#comment-4952</guid>
		<description>There is, however, one example for a single gene that is capable of changing a complex behaviour:

&lt;a href=&quot;http://www.nytimes.com/2005/06/03/science/03cell.html?ex=1180152000&amp;en=f5f81fe0ac54ceac&amp;ei=5070&quot; rel=&quot;nofollow&quot;&gt;http://www.nytimes.com/2005/06/03/science/03cell.html?ex=1180152000&amp;en=f5f81fe0ac54ceac&amp;ei=5070&lt;/a&gt;

Is it the sex gene then? (It has no homolg in humans)

The same group recently published a follow up in nature.</description>
		<content:encoded><![CDATA[<p>There is, however, one example for a single gene that is capable of changing a complex behaviour:</p>
<p><a href="http://www.nytimes.com/2005/06/03/science/03cell.html?ex=1180152000&amp;en=f5f81fe0ac54ceac&amp;ei=5070" rel="nofollow">http://www.nytimes.com/2005/06/03/science/03cell.html?ex=1180152000&#038;en=f5f81fe0ac54ceac&#038;ei=5070</a></p>
<p>Is it the sex gene then? (It has no homolg in humans)</p>
<p>The same group recently published a follow up in nature.</p>
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