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Under-Cabinet Range Hoods

Update of
http://www.the-scientist.com/community/posts/list/140/122.page#2321

Recapitulation of some earlier notes on the
Scientific Comprehension Of The Origin, Drive, Nature And Purpose Of Life

A. Uniqueness Of science among human artifacts

ALL aspects of our culture are, of course, anthropoartifacts, including science. Yet among those artifacts science has a distinct uniqueness for us.

During the recent several centuries in the course of human history humans have been developing science at an accelerating rate as a provider of convincing, ever closer approaching, approximate models of the real world.

B. Origin and nature of life

28Dec09 Implications Of E=Total[m(1 + D)]
http://www.the-scientist.com/community/posts/list/184.page#4587

Astronomically there are two “physics”, a “classical physics” system of and between galactic clusters, and a “quantum physics” system WITHIN the galactic clusters.

The onset of big-bang’s inflation started gravity, followed by formation of galactic clusters that behave as accelerating Newtonian bodies while continuously reconverting their shares of pre-inflation masses back to energy, that continuously fuels their ongoing expansion, and of endless intertwined evolutions WITHIN the clusters in attempts to resist-postpone this reconversion.

As mass is just another face of energy it is commonsensible to regard not only life, but mass in general, as a format of temporarily constrained energy.

It therefore ensues that whereas the in-space expanding cosmic constructs, the galaxies clusters, are – overall – continuously converting their original pre-inflation mass back to energy, the overall evolution WITHIN them, within the clusters, is in the opposite direction, temporarily constrained energy packages such as black holes and biospheres and other energy-storing mass-formats are precariuosly forming and “doing best” to survive “as long as possible”.

C. The drive and nature of Earth life

Earth life Genesis, formation of the first genes, was a phenomenon of serendipitous occurrence, in a supportive environment, of ‘favourably-coursed’ energy potential between in-coming sun radiation and in-water polymerizing-precipitating RNA-related oligomeric configurations.

The drive of Earth life and of its evolution is to enhance the functionality and survivability of Earth’s genes, in order to maintain and enhance Earth-biosphere’s temporary constrained energy storage, to maintain the biosphere BIO as long as possible.

The RNA genes are life’s prime strata organisms. They evolved their DNA-images as their organ, their continuously updated operational worklogs primal Earth’s organisms libraries, and genomed them, i.e. nucleusized them, and celled them with their other organ, the outer cell membrane.

It is the RNA genes and their DNA replicas, life’s prime strata organisms, that evolve, and the evolution of genomes, the 2nd stratum of life, and of the 3rd life stratum cellular organisms, is an interenhancing consequence of their genes’ evolution.

D. The formation of Earth life

Earth Life: 1. a format of temporarily constrained energy, retained in temporary constrained genetic energy packages in forms of genes, genomes and organisms 2. a real virtual affair that pops in and out of existence in its matrix, which is the energy constrained in Earth’s biosphere.

Earth organism: a temporary self-replicable constrained-energy genetic system that supports and maintains Earth’s biosphere by proliferating and maintenance of genes.

Gene: the primal Earth’s organism and/or its functional DNA replicas. (1st stratum organism)

Genome: a multigenes organism, comprising the genes operational replicas-work-patterns, an organ of the primal Earth’s genes, consisting of a cooperative commune of its member genes. (2nd stratum organism)

Cellular organisms: mono- or multi-celled Earth organisms. (3rd stratum organism)

E. Update of underlying life sciences conception is thus feasible

- First were independent individual RNA genes, Earth’s primal organisms.

- Genes aggregated cooperatively into genomes, RNA or their DNA replicas multigenes organisms, with genomes’ organs.

- Simultaneously or consequently genomes evolved protective-functional membranes, their organs.

- Then followed cellular organisms, with a variety of outer-cell membrane shapes and
functionalities and a variety of inter- and intracell processes.

This is a scientific, NOT A TECHNICAL, life-science conception.

It is tomorrow’s comprehension of life and of its evolution.

IT IS FRAUGHT WITH INTRIGUING DARWINIAN EVOLUTION IMPLICATIONS.

IT IS FRAUGHT WITH INTRIGUING TECHNOLOGICAL DEVELOPMENTS POTENTIALS.

F. The purpose of OUR, human, life

The purpose of OUR life and of its promotion is ours to formulate and set. It derives solely from our cognition.

Suggesting,

Dov Henis
(Comments from 22nd century)

Cosmic Evolution Simplified
http://www.the-scientist.com/community/posts/list/240/122.page#4427

http://profiles.yahoo.com/blog/2SF3CJJM5OU6T27OC4MFQSDYEU?num=5&max=160&start=0

Genomes Are RNAs’-Made Patterns-Manuals

“Repeats protect DNA”
http://www.the-scientist.com/blog/display/57135/

“More On Evolution In The Still RNA World”
http://www.the-scientist.com/community/posts/list/260/122.page#4818

Fitting together the pieces of the “still an RNA world” puzzle ?

- Rational probability and possibility that the initial, independent pre-biometabolism direct sunlight-fueled genes (life) were RNAs, who evolved their DNA-images as operational patterns-manuals libraries, and celled and genomed them. They most probably synthesized (and nucleusized) their DNAs manual libraries as their functional organs, to serve as their environmentally stabler than RNA, than themselves, works memory cores.

- Rational possibility that ALL RNAs represent the original archae-genes that since their (life) genesis have been and still are the primary actors, assessors, messengers, operators of all life processes.

- Rational possibility that the RNAs are the environmental feedback communicators to, and modifiers of, the genomes, that the RNAs are the effectors of the desirable biased genes expressions modifications, of enhanced energy constraining for survival.

Dov Henis
(Comments From The 22nd Century)
28Dec09 Implications Of E=Total[m(1 + D)]
http://www.the-scientist.com/community/posts/list/184.page#4587
Cosmic Evolution Simplified
http://www.the-scientist.com/community/posts/list/240/122.page#4427

What Came First in the Origin of Life? New Study Contradicts the ‘Metabolism First’ Hypothesis
http://www.sciencedaily.com/releases/2010/01/100108101433.htm

Dov Henis
(Comments From The 22nd Century)
Updated Life’s Manifest May 2009
http://www.the-scientist.com/community/posts/list/140/122.page#2321
28Dec09 Implications Of E=Total[m(1 + D)]
http://www.the-scientist.com/community/posts/list/184.page#4587
Cosmic Evolution Simplified
http://www.the-scientist.com/community/posts/list/240/122.page#4427

PS: Just reflect about sleep and chirality… DH

With respect to RNA and amino acids, a nice paper was published by Sutherland and Mullen I think in 2007 in a german chemistry journal, Angewandte Chemie, where they activate ribonucleotides, as well as make amino acid amides.

Years of work making two halves that then could not be joined.

In the so-called RNA world, this versatile molecule acted both like DNA (storing genetic information) and proteins (carrying out chemical reactions, such as building new RNA molecules).

One hypothesized task I’ve seen is that RNA acts to concentrate and activate mono- or diamino acids, which likely preceded it. It is probable that in prebiotic chemistry a little bit of ‘everything’ happened simultaneously.

That is by the way a prediction that this result tests positive for as phospate isn’t just an afterthought but contribute to the result. In the same sense, what is then less promising is that I hear they still had to purify in between steps.

Now I wonder if they could simplify (well, sort of since 4 reactions is really simple) by using glycine instead of ribose as backbone. GNA is a putative pre-RNA compound, doing the same task with an even simpler molecule. Again, perhaps initially both GNA and RNA was in play.

This work has been ongoing for years. The conspiracy theories merely make me laugh, and smells of pathetiscm (even though it’s not a real word I shall use it here). This is a bit like a bomb dropping on the heads of a creationist, metabolist or whatever other theory you believe in.

Give me some hard facts, I’m open minded and ready to be convinced.

Start here:

http://www.panspermia.org/archindex.htm

That should keep you busy for a while!!

It’s been tried and it doesn’t work. Which means it happened in another way. This work isn’t a ‘side step’, it’s an alternative way of the first few steps to getting to RNA.

Panspermia? Please provide some sort of evidence. An iota of it would be a start.

They are on a fool’s errand.

Cosmic Ancestry (panspermia) answers most of the questions WRT the origin of life on earth.

With all due respect to Dr. Robert Shapiro, who has been commentating on this recently published work, and who advocates the ‘Metabolism’ first hypothesis, this is a piece of work that is purely experimental with little or no hypothetical conjecture.

Is it not true that we have to base science on facts? It is very easy to be cynical and criticise work, but if one does need to oppose one theory and propose an alternative, as Dr Shapiro has done in this case, should it not be backed up with some sort of evidence?

Indeed it is true that Professor Eschenmoser once stated, and forgive me if it is slightly misworded, that:

‘The origins of life cannot be rediscovered, it must be reinvented’.

Let us say that this work is an example of what MAY have happened. What has been shown in this research may have not been the case. We will never know, but it is a strong contribution of what may have taken place on primordial earth. I call on those who would like to contest the ‘RNA world’ or an ‘RNA world + X’ hypothesis to disclose some sort of evidence otherwise.