Comments on: Your Inner Blob http://blogs.discovermagazine.com/loom/2009/06/09/your-inner-blob/ A blog about life, past and future. Written by DISCOVER contributing editor and columnist Carl Zimmer. Tue, 24 Nov 2009 16:41:26 -0600 http://wordpress.org/?v=2.8.4 hourly 1 By: Jo http://blogs.discovermagazine.com/loom/2009/06/09/your-inner-blob/comment-page-1/#comment-19246 Jo Wed, 10 Jun 2009 19:41:29 +0000 http://blogs.discovermagazine.com/loom/2009/06/09/your-inner-blob/#comment-19246 Such a strange thing, to be informed of what my own cells are up to. All this activity going on, each one its own little entity going about its business, and collectively they are somehow 'me'. Life is fascinating. Such a strange thing, to be informed of what my own cells are up to. All this activity going on, each one its own little entity going about its business, and collectively they are somehow ‘me’.

Life is fascinating.

]]> By: Nike Kobe IV http://blogs.discovermagazine.com/loom/2009/06/09/your-inner-blob/comment-page-1/#comment-19240 Nike Kobe IV Wed, 10 Jun 2009 14:49:36 +0000 http://blogs.discovermagazine.com/loom/2009/06/09/your-inner-blob/#comment-19240 Another point of added information I thought of while reading the last few paragraphs of your article was a recent seminar I saw by Scott A. Another point of added information I thought of while reading the last few paragraphs of your article was a recent seminar I saw by Scott A.

]]> By: Kris http://blogs.discovermagazine.com/loom/2009/06/09/your-inner-blob/comment-page-1/#comment-19233 Kris Wed, 10 Jun 2009 03:05:32 +0000 http://blogs.discovermagazine.com/loom/2009/06/09/your-inner-blob/#comment-19233 Great article Carl! I instantly thought of my housemate - Chi Pak- who has a wonderful article in Nature Neurosciecne http://www.nature.com/nrn/journal/v9/n2/abs/nrn2236.html explaining the different actin binding proteins/ depolymerizing factors that facilitate treadmilling in different ways. I did a rotation in Dr. James Bamburg's Lab (where Chi works) at Colorado State and man did I get a large does of ADF/Cofilin. It was great fun and I learned a lot. Another point of added information I thought of while reading the last few paragraphs of your article was a recent seminar I saw by Scott A. Weed PhD. he is researching "invadopodia" the cell protrusions that invade surrounding tissue during metastasis. He mentioned some specific compounds that are in phase 2 trials as anti-cancer that specifically target the moving "invadopdia" but leave the background cytoskeletons alone. The title of his talk was "Regulation of Cytoskeletal signaling pathways in tumor cell invasion" hope this gives you and your readers some worthy extra thoughts to ponder. Cheers -Kris Great article Carl! I instantly thought of my housemate – Chi Pak- who has a wonderful article in Nature Neurosciecne http://www.nature.com/nrn/journal/v9/n2/abs/nrn2236.html explaining the different actin binding proteins/ depolymerizing factors that facilitate treadmilling in different ways. I did a rotation in Dr. James Bamburg’s Lab (where Chi works) at Colorado State and man did I get a large does of ADF/Cofilin. It was great fun and I learned a lot.

Another point of added information I thought of while reading the last few paragraphs of your article was a recent seminar I saw by Scott A. Weed PhD. he is researching “invadopodia” the cell protrusions that invade surrounding tissue during metastasis. He mentioned some specific compounds that are in phase 2 trials as anti-cancer that specifically target the moving “invadopdia” but leave the background cytoskeletons alone.
The title of his talk was
“Regulation of Cytoskeletal signaling pathways in tumor cell invasion”

hope this gives you and your readers some worthy extra thoughts to ponder.
Cheers
-Kris

]]> By: John S. Wilkins http://blogs.discovermagazine.com/loom/2009/06/09/your-inner-blob/comment-page-1/#comment-19232 John S. Wilkins Wed, 10 Jun 2009 00:35:25 +0000 http://blogs.discovermagazine.com/loom/2009/06/09/your-inner-blob/#comment-19232 I haven't read it yet, but I bet you're actin on inside information... I haven’t read it yet, but I bet you’re actin on inside information…

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