Preregistration for All Medical Animal Research

By Neuroskeptic | July 23, 2014 12:13 pm

Writing in the European Journal of Clinical Investigation, three Dutch researchers say that All preclinical trials should be registered in advance in an online registry


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Babylonian Neurology and Psychiatry

By Neuroskeptic | July 20, 2014 2:43 pm

A fascinating little paper in Brain examines Neurology and psychiatry in Babylon. It’s a collaboration by British neurologist Edward H. Reynolds and Assyriologist James V. Kinnier Wilson.

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There’s A Place For Heroic Gambles In Science

By Neuroskeptic | July 16, 2014 11:48 am

Over at Paul Knoepfler’s excellent Stem Cell Blog, commenter Robert Geller (@rjgeller) offers some remarkable data about the hiring of a disgraced scientist.

Geller queries why Haruko Obokata, the biologist at the center of the “STAP” stem cell scandal, was ever given her job. Obokata is a Research Unit Leader (RUL) at Japan’s national Riken Center for Developmental Biology (CDB). It was after being appointed to this prestigious post that she completed and published her discovery of “STAP cells” – supposedly a new kind of way of making stem cells. Her data turned out to be serious flawed and Obokata’s two papers on STAP were retracted in Nature earlier this month. But should she have been hired in the first place?

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Can We Grasp The Brain’s Complexity?

By Neuroskeptic | July 14, 2014 1:48 pm

An entertaining paper just out in Frontiers in Systems Neuroscience offers a panoramic view of the whole of neuroscience: Enlarging the scope: grasping brain complexity

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CATEGORIZED UNDER: funny, papers, science, select, Top Posts

Interview: What’s wrong with the Human Brain Project?

By Neuroskeptic | July 11, 2014 5:42 am

The hot story in neuroscience this week has been the controversy over Europe’s Human Brain Project (HBP). On Monday, 156 neuroscientists signed an open letter calling for major reforms of the ambitious program, and pledging to boycott it if things don’t change.

hbp logo

Since then, the number of signatories on the letter’s site has grown to nearly 600. The HBP released an official response on Wednesday.

I emailed Zach Mainen, one of the drafters of the open letter, for comment.

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On “On the emptiness of failed replications”

By Neuroskeptic | July 7, 2014 1:36 pm

Harvard neuroscientist Jason Mitchell has written a piece called On the emptiness of failed replications

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fMRI Motion Correction: The Quick and the Dead

By Neuroskeptic | July 6, 2014 1:13 pm

The infamous dead salmon brain scan study may just have been eclipsed, in the ‘most ghoulish demonstration of a methodological pitfall in fMRI‘ stakes. A new study examines the issue of motion artifacts, a major concern in much neuroimaging research – and it does so by scanning dead people.

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Is It Time To Redraw the Map of the Brain?

By Neuroskeptic | July 1, 2014 3:47 am

A provocative and important paper just out claims to have identified a pervasive flaw in many attempts to map the function of the human brain.

University College London (UCL) neuroscientists Yee-Haur Mah and colleagues say that in the light of their findings, “current inferences about human brain function and deficits based on lesion mapping must be re-evaluated.”

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CATEGORIZED UNDER: methods, papers, select, Top Posts

Another Education Neuromyth Debunked

By Neuroskeptic | June 29, 2014 5:36 am

What does neuroscience have to say about the educational value of lectures?

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The FDA’s Antidepressant Warning Didn’t Really “Backfire”

By Neuroskeptic | June 24, 2014 5:31 am

We read this week that

‘Black Box’ Warning on Antidepressants Raised Suicide Attempts
A so-called “black box” warning on antidepressants that the medications increase the risk of suicidal thinking and behavior in kids may have had a horrible side-effect. New research finds the warning backfired, causing an increase in suicide attempts by teens and young adults.

The research in question is this paper in the British Medical Journal from Harvard researchers Christine Lu and colleagues.

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