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	<title>Reality Base &#187; drugs</title>
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	<link>http://blogs.discovermagazine.com/realitybase</link>
	<description>A blog about science, politics, and how to let each help the other without compromising them both.</description>
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		<title>Drug Industry 1, Country 0: Big Pharma Can Now Hawk Unapproved Drugs</title>
		<link>http://blogs.discovermagazine.com/realitybase/2009/01/14/drug-industry-1-country-0-big-pharma-can-now-hawk-unapproved-drugs/</link>
		<comments>http://blogs.discovermagazine.com/realitybase/2009/01/14/drug-industry-1-country-0-big-pharma-can-now-hawk-unapproved-drugs/#comments</comments>
		<pubDate>Wed, 14 Jan 2009 23:14:35 +0000</pubDate>
		<dc:creator>Melissa Lafsky</dc:creator>
				<category><![CDATA[Health Care]]></category>
		<category><![CDATA[drugs]]></category>
		<category><![CDATA[FDA]]></category>
		<category><![CDATA[medicine]]></category>

		<guid isPermaLink="false">http://blogs.discovermagazine.com/realitybase/2009/01/14/drug-industry-1-country-0-big-pharma-can-now-hawk-unapproved-drugs/</guid>
		<description><![CDATA[From the wires: The FDA has just completed a fresh set of guidelines that will permit pharmaceutical companies to tell doctors about unapproved uses of their medicines—in effect, giving big pharma carte blanche to hawk unapproved drugs.
Specifically, the new regulations allow drug companies to &#8220;distribute copies of medical journal articles that describe unapproved uses&#8221; of [...]]]></description>
			<content:encoded><![CDATA[<p><a href="http://www.nytimes.com/2009/01/13/business/13label.html" target="_blank">From the wires</a>: The FDA has just completed a fresh set of guidelines that will permit pharmaceutical companies to tell doctors about unapproved uses of their medicines—in effect, giving big pharma carte blanche to hawk unapproved drugs.</p>
<p>Specifically, the new regulations allow drug companies to &#8220;distribute copies of medical journal articles that describe unapproved uses&#8221; of their drugs to all the doctors they want.</p>
<p>Technically this reg isn&#8217;t new; it was in place until 2006, then lapsed until industry lobbyists made sure it was proposed again last year, despite heavy criticism from Democrats and drug industry critics. And now, conveniently one week before the Bush administration draws its final, sputtering breath, the rule has made its way back into the final FDA guidelines.</p>
<p>Big pharma spokespeople pooh pooh the reg as <a href="http://finance.yahoo.com/news/FDA-OKs-sharing-unapproved-apf-14036181.html" target="_blank">nothing more than a formality</a>: &#8220;Physicians need timely access to the latest medical information to keep abreast of the best practices in patient care,&#8221; said Alan Bennett, an attorney representing the pharmaceutical industry.</p>
<p><span id="more-392"></span></p>
<p>It&#8217;s true that these journal articles are required to be peer-reviewed—though whether that means anything <a href="http://finance.yahoo.com/news/FDA-OKs-sharing-unapproved-apf-14036181.html" target="_blank">remains to be seen</a>:</p>
<blockquote><p>The reliability of medical journal articles came into question earlier this year when drugmaker Merck &amp; Co. Inc. was accused of ghostwriting several articles about its painkiller Vioxx, which was withdrawn from the market in 2004 for safety reasons.</p>
<p>Reports published in the Journal of the American Medical Association alleged that Merck paid academics to take credit for articles which were actually written by the company. Merck denied the allegations, calling them false and misleading.</p></blockquote>
<p>For every <a href="http://blogs.discovermagazine.com/realitybase/2009/01/05/bye-bye-freebies-drug-companies-ax-free-goodies-to-doctors/">one step forward</a>, two steps back.</p>
<p>Related:<br />
RB: <a href="http://blogs.discovermagazine.com/realitybase/2009/01/05/bye-bye-freebies-drug-companies-ax-free-goodies-to-doctors/">Bye Bye Freebies! Drug Companies Ax Free Goodies to Doctors</a><br />
RB: <a href="http://blogs.discovermagazine.com/realitybase/2008/12/19/is-nothing-sacred-nobel-prize-engulfed-in-drug-company-scandal/">Is Nothing Sacred? Nobel Prize Engulfed in Drug Company Scandal</a><br />
RB: <a href="http://blogs.discovermagazine.com/realitybase/2008/12/04/clinic-to-reveal-all-doctor-drug-industry-ties-on-the-internet/">Clinic to Reveal All Doctor-Drug Industry Ties on the Web</a></p>
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		<slash:comments>12</slash:comments>
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		<title>Weekly News Roundup: &#8216;Twas the Night Before Jan. 20</title>
		<link>http://blogs.discovermagazine.com/realitybase/2008/12/19/weekly-news-roundup-twas-the-night-before-jan-20/</link>
		<comments>http://blogs.discovermagazine.com/realitybase/2008/12/19/weekly-news-roundup-twas-the-night-before-jan-20/#comments</comments>
		<pubDate>Fri, 19 Dec 2008 18:46:41 +0000</pubDate>
		<dc:creator>Melissa Lafsky</dc:creator>
				<category><![CDATA[Discover's Science Policy Project]]></category>
		<category><![CDATA[The 2008 Election]]></category>
		<category><![CDATA[crime]]></category>
		<category><![CDATA[drugs]]></category>
		<category><![CDATA[greed]]></category>
		<category><![CDATA[technology]]></category>

		<guid isPermaLink="false">http://blogs.discovermagazine.com/realitybase/2008/12/19/weekly-news-roundup-twas-the-night-before-jan-20/</guid>
		<description><![CDATA[
• Where have we seen this before? A President&#8217;s Guide to Science, in video form.
• A holy union of incentives and science:  A car key that disables cell phones when the car is in use.
• Will the hordes of laid-off techies be driven to crime?
• All this carbon offsetting and greening is nice and [...]]]></description>
			<content:encoded><![CDATA[<p><script src="http://w.sharethis.com/widget/?wp=2.3.1&amp;publisher=67cc06de-58af-40be-9e8e-7c994abde46a" type="text/javascript" charset="utf-8"></script></p>
<p>• Where have we <a href="http://blogs.discovermagazine.com/realitybase/category/discovers-science-policy-project/">seen this before</a>? A <a href="http://video.google.com/videoplay?docid=-1424386236177531815" target="_blank">President&#8217;s Guide to Science</a>, in video form.</p>
<p>• A holy union of incentives and science:  A car key that <a href="http://www.newswise.com/articles/view/547297/?sc=rssn" target="_blank">disables cell phones when the car is in use</a>.</p>
<p>• Will the hordes of laid-off techies <a href="http://news.zdnet.com/2424-9595_22-255464.html" target="_blank">be driven to crime</a>?</p>
<p>• All this carbon offsetting and greening is nice and all, but the <a href="http://blog.wired.com/wiredscience/2008/12/oil-not-the-cli.html" target="_blank">elephant in the room is still coal</a>.</p>
<p>• Any chemists want to weigh in on <a href="http://www.adn.com/news/alaska/crime/story/628010.html" target="_blank">what type of drugs can be manufactured at home</a>?</p>
<p>• When Madoff strikes, <a href="http://gristmill.grist.org/story/2008/12/16/142656/61" target="_blank">no sustainable food business is safe</a>.</p>
<p>• And finally, the perfect Christmas medley: <a href="http://www.msnbc.msn.com/id/28300535/" target="_blank">electronics meets art</a> meets taut consumerist criticism.</p>
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		<slash:comments>10</slash:comments>
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		<title>Bad Idea of the Day: Governments Prescribing Heroin</title>
		<link>http://blogs.discovermagazine.com/realitybase/2008/12/01/bad-idea-of-the-day-governments-prescribing-heroin/</link>
		<comments>http://blogs.discovermagazine.com/realitybase/2008/12/01/bad-idea-of-the-day-governments-prescribing-heroin/#comments</comments>
		<pubDate>Mon, 01 Dec 2008 18:53:25 +0000</pubDate>
		<dc:creator>Melissa Lafsky</dc:creator>
				<category><![CDATA[Health Care]]></category>
		<category><![CDATA[addiction]]></category>
		<category><![CDATA[drugs]]></category>
		<category><![CDATA[switzerland]]></category>

		<guid isPermaLink="false">http://blogs.discovermagazine.com/realitybase/2008/12/01/bad-idea-of-the-day-governments-prescribing-heroin/</guid>
		<description><![CDATA[
What would happen if the U.S. government announced a new obesity-fighting initiative whereby every chronically obese person in the country was given up to two federally-funded Big Macs a day? That&#8217;s basically the plan of attack Switzerland is taking with its heroin addicts. The BBC reports that the Swiss have passed a &#8220;radical&#8221; health policy [...]]]></description>
			<content:encoded><![CDATA[<p><script src="http://w.sharethis.com/widget/?wp=2.3.1&amp;publisher=67cc06de-58af-40be-9e8e-7c994abde46a" type="text/javascript" charset="utf-8"></script></p>
<p>What would happen if the U.S. government announced a new obesity-fighting initiative whereby every chronically obese person in the country was given up to two federally-funded Big Macs a day? That&#8217;s basically the plan of attack Switzerland is taking with its heroin addicts. The BBC <a href="http://news.bbc.co.uk/2/hi/europe/7757050.stm" target="_blank">reports</a> that the Swiss have passed a &#8220;radical&#8221; health policy that allows long-term addicts to receive the drug at government clinics, free of charge.</p>
<p>A whopping sixty-eight percent of voters supported the policy, which would allow addicts to inject the drug up to twice a day under medical supervision. Granted, the scheme has some benefits: it increases control of needle use and disposal, provides incentives for addicts to come into clinics regularly and be treated for other medical or psychological problems, and removes the need for them to resort to crime to pay for their habit. Part of the bill&#8217;s popularity also comes from the fact that the scheme has already been underway in Zurich for 14 years, and many consider it successful.</p>
<p>Still, at the end of the day, the bill is exactly what it sounds like: a plan to have the government pay to shoot its citizens up with expensive and extremely dangerous drugs.</p>
<p><span id="more-348"></span></p>
<p>It&#8217;s hard to imagine that lesser alternatives, like offering free <a href="http://www.whitehousedrugpolicy.gov/publications/factsht/methadone/" target="_blank">methadone</a> instead of a syringe full of Harry Jones, wouldn&#8217;t be a better plan, even for the worst addicts. And it would be interesting to see whether Zurich has seen any unintended consequences from its free heroin policy, such as an increase  in the number of heroin users who cross the line to addiction or a migration of hardcore addicts in search of a free and unlimited source of smack.</p>
<p>And for the day&#8217;s big dose of irony, in another referendum vote at around the same time, 63 percent of the country voted against de-criminalizing cannabis. <a href="http://www.druglibrary.org/schaffer/hemp/general/bruin.htm" target="_blank">Where to even begin on that one</a>.</p>
]]></content:encoded>
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		<slash:comments>9</slash:comments>
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		<title>The Meds Made Me Do It! Drug Side Effects Include Gambling, Risky Sex</title>
		<link>http://blogs.discovermagazine.com/realitybase/2008/07/16/the-meds-made-me-do-it-drug-side-effects-include-gambling-risky-sex/</link>
		<comments>http://blogs.discovermagazine.com/realitybase/2008/07/16/the-meds-made-me-do-it-drug-side-effects-include-gambling-risky-sex/#comments</comments>
		<pubDate>Wed, 16 Jul 2008 16:14:33 +0000</pubDate>
		<dc:creator>Melissa Lafsky</dc:creator>
				<category><![CDATA[Health Care]]></category>
		<category><![CDATA[Science in the Courtroom]]></category>
		<category><![CDATA[drugs]]></category>
		<category><![CDATA[gambling]]></category>

		<guid isPermaLink="false">http://blogs.discovermagazine.com/realitybase/2008/07/16/the-meds-made-me-do-it-drug-side-effects-include-gambling-risky-sex/</guid>
		<description><![CDATA[Here&#8217;s some news that could put an interesting twist in the gambling addiction/genetics debate (not to mention supply new reasons to sue drug companies): ABC News reports that several of the drugs prescribed for Parkinson&#8217;s disease and restless legs syndrome can cause a range of dangerous behavioral side effects including increased drinking, drug use, risky [...]]]></description>
			<content:encoded><![CDATA[<p>Here&#8217;s some news that could put an interesting twist in the <a href="http://blogs.discovermagazine.com/realitybase/2008/06/25/brain-research-for-sale-gaming-industry-looks-to-science-to-beat-class-action/" target="_blank">gambling addiction/genetics debate</a> (not to mention supply new reasons to sue drug companies): ABC News <a href="http://abcnews.go.com/Health/story?id=5374153&amp;page=1" target="_blank">reports</a> that several of the drugs prescribed for Parkinson&#8217;s disease and restless legs syndrome can cause a range of dangerous behavioral side effects including increased drinking, drug use, risky sex, and gambling.</p>
<p>The drugs, which include Mirapex and Requip, are dopamine agonists, which mimic dopamine in the brain to boost the movement and coordination centers—and also stimulate the pleasure response by reinforcing certain behaviors. Unwitting patients who&#8217;ve taken the drugs have wound up with costly gambling habits, DUI arrests, and compulsive eating disorders, as well as even stranger effects—one man reportedly <a href="http://abcnews.go.com/Health/Story?id=5374153&amp;page=3" target="_blank">plays basketball for up to 36 hours</a> at a time, while another compulsively fishes.</p>
<p>Given that more than 10 million prescriptions have been written for Mirapex alone, it&#8217;s not unlikely that we&#8217;ll see some serious fallout, be it motorists killed by a drunk driver on the drug, or an STD spike as a result of risky sexual practices (which are <a href="http://blogs.discovermagazine.com/realitybase/2008/07/09/yet-another-health-care-woe-boomers-getting-the-clap/" target="_blank">already on the rise among seniors</a>, the demographic most likely to be taking meds for Parkinson&#8217;s and RLS).</p>
<p>As such, it&#8217;s worth it to start asking to what degree patients should be held legally responsible for their actions while taking the drug—and, perhaps even more importantly for lawyers, whether the drug companies can be held at all responsible for all that irresponsible boozing and sex.</p>
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		<slash:comments>161</slash:comments>
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