Tag: Open Thread

Open Thread, 11/24/13

By Razib Khan | November 24, 2013 4:21 am

23andMe

One of the stranger call-ins on my interview with Kathleen Dunn last month was when a woman who proudly declared that she was a math major in college asserted that 23andMe had told her she wasn’t at risk for many diseases which now in her 60s she had developed. I didn’t want to be too pointed about it, but if you are in your 60s you are at risk for developing many illnesses no matter what your “genetic risk.” This is clear from 23andMe’s statistics, which display high baseline risks for many common diseases. From reading comments on 23andMe discussion forums it seems that perceived false negatives are going to be a much bigger issue than false positives over the long run. If the tests are “wrong” in a direction which leaves you in a better state than predicted you might feel like you’ve dodged a bullet. On other hand if the tests are “wrong” in a direction which gave you false comfort, or add insult to injury when you’ve developed a debilitating disease, then you feel much more burned.

I don’t really recommend blogs too much anymore. But please check out The Stage and Social Evolution Forum.

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Open Thread, 11/17/2013

By Razib Khan | November 17, 2013 7:22 pm

Finished J. P. Mallory’s The Origins of the Irish. Good book, but it was as illuminating as to the origins of the Irish as Danel Dennett’s Consciousness Explained was in explaining consciousness.

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Open Thread, 11/10/2013

By Razib Khan | November 10, 2013 1:35 pm

Change is the only constant.

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Open Thread, 11/3/2013

By Razib Khan | November 3, 2013 12:34 pm

Origins-of-the-Irish1After reading Ancestral Journeys, I decided to get J. P. Mallory’s The Origins of the Irish. A bit on the academic side for some, but definitely a good dive into the literature. Mallory is well aware of the latest genetic research, so this is as up-to-date as it gets. It’s a good case study in how multidisciplinary prehistoric studies should be done.

As I’ve suggested earlier prehistory looks to be a good deal more complex than we had previous thought, so expanding beyond single methodological perspectives is probably essential if we really care about truth.

In other news, a short piece in The New York Times refers to Salafis as ‘ultraconservative.’ I think this misleads most people about the nature of Salafism: it is a radical utopian system which recently arose out of Islam’s confrontation with Western derived modernity. It isn’t conserving anything. This aspect of Salafism explains why Saudi Arabia condones the bulldozing of Muhammed’s tomb and celebrates modern monumental architecture in Islam’s holy city.

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Open Thread, 10/20/2013

By Razib Khan | October 20, 2013 11:43 am

Beginnings and endings.

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Open Thread, 10/13/2013

By Razib Khan | October 13, 2013 2:08 am

Six months back there was a lot of discussion of Y haplogroup A00, An African American Paternal Lineage Adds an Extremely Ancient Root to the Human Y Chromosome Phylogenetic Tree. Now there’s an attempt by some of the researchers on that paper to raise money to collect more samples. Which of Cameroon’s peoples have members of haplogroup A00?:

This is Round Two of our fundraising for our groundbreaking research on the world’s earliest-branching Y-chromosome lineage, A00. Its origins lie in the earliest days of humanity’s emergence, the exact time very much in debate, but almost surely over 200,000 years ago. We first discovered it in early 2012, when the results of the Perrys’ Y-DNA tests were unlike anything seen before. We learned that they have matches among some of the diverse peoples of Southwest Cameroon. The new samples to be collected by Matthew in his homeland will allow us to learn much more about A00.

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Open Thread, 10/6/2013

By Razib Khan | October 6, 2013 2:14 am

Questions?

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Open Thread, 9/29/2013

By Razib Khan | September 29, 2013 10:14 pm

Back from Canine Feline Genomics Conference. Turns out most variation between dog breeds may be due to correlated allele frequency differences, not fixed ones (i.e., Lewontin’s Fallacy applies to dogs too!).

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Open Thread, 9/22/2013

By Razib Khan | September 22, 2013 4:46 am

I found this broadside against intellectual ignorance by Christoper Beckwith rather amazing and enjoyable. Long time readers will be aware that I am a fan of his Empires of the Silk Road. In any case, I have noticed that many of my friends and acquaintances use the term ‘ignorance’ to connote a set of views which they find normatively offensive. That is not my preferred usage of the term. Rather, I take it rather at its face value as denoting those who are lacking in the basic facts from which to even attempt audacious inference. The latter I appreciate. The former I detest.

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Open Thread, 9/15/2013

By Razib Khan | September 15, 2013 4:39 pm

How do people manage to keep track of the scientific literature in their area?

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Open Thread, 9/7/2013

By Razib Khan | September 8, 2013 2:00 am

I hope we don’t bomb Syria. El Yucateco XXXtra Hot Kutbil-ik Mayan Style Habanero Hot Sauce is delicious.

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Open Thread, 09/01/2013

By Razib Khan | September 1, 2013 1:01 am

This is probably the longest stretch of time with me not posting much since May/June of 2010. But I’ll be back to offering my opinions and analyses soon enough. Also, I should probably mention that I’ll be presenting at the 7th International Conference on Advances in Canine and Feline Genomics and Inherited Diseases (a.k.a. the cat & dog conference) at the end of the month (I’ll be in Cambridge/Boston 23rd to 29th). I’ll be rather busy the whole week, but I thought I would mention it in case some readers see someone who looks like me around the Broad Institute and are curious. Higher chance than normal that it is me.

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Open Thread, 08/25/2013

By Razib Khan | August 24, 2013 1:00 am

Very excited that my daughter was thumbing through The Genetical Theory of Natural Selection yesterday. Previous to this she took a fancy to Christian Meeir’s Caesar: A Biography.

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Open Thread, 08/18/2013

By Razib Khan | August 18, 2013 12:10 pm

I probably won’t be posting much in the second half of August. Just a note. Twitter feed will be active(ish) though.

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Open Thread, 08/11/2013

By Razib Khan | August 11, 2013 12:14 am

Summer is racing….

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Open Thread, 8/4/2013

By Razib Khan | August 4, 2013 1:00 pm

I thought it might be useful for new readers to understand a bit about my comments policy and how I’ve come this stance. Let me give you an example of one individual who occasionally left comments on my blog, often combative, though just on the legitimate side of the trolling boundary. One of the major tactics of argument of this individual was to impute upon me particular life experiences which he thought I must have had, and so shaped my opinions. Though I do not share much about my personal life online, I do go by my “real name,” and over 11+ years of writing on the internet one can construct a rough narrative from stray anecdotes. The key is though that this picture is rough. After one exchange where my interlocutor made an inference based on his own perception of various likelihoods about me, I tired of the one sided game (he was anonymous), and looked him upon on Facebook. I left a quick comment to that effect, and asserted now the scales were somewhat balanced. He never left a comment after that incident.

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Open thread, 7/30/2013

By Razib Khan | July 30, 2013 12:09 am

Sorry, this was late. Was out of town, showing my daughter the sites of the world….

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Open Thread, 7/21/2013

By Razib Khan | July 21, 2013 2:03 pm

Definitely summer….

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Open Thread, 7/14/2013

By Razib Khan | July 14, 2013 12:43 pm

Mid-July is here. Time flies. Also, if you haven’t check out PubChase if you need something to manage your papers and give you recommendations.

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Open Thread, 7/7/2013

By Razib Khan | July 7, 2013 1:34 am

Worth following this week, #smbe13 hashtag on Twitter (I will be).

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This blog is about evolution, genetics, genomics and their interstices. Please beware that comments are aggressively moderated. Uncivil or churlish comments will likely get you banned immediately, so make any contribution count!
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